CAS 99287-08-8

defensin hnp-1 human

Description:

Defensin HNP-1 (Human Neutrophil Peptide 1) is a member of the defensin family, which are small cationic peptides that play a crucial role in the innate immune response. This peptide is primarily produced by neutrophils and exhibits antimicrobial properties, effectively targeting a wide range of pathogens, including bacteria, fungi, and viruses. HNP-1 is characterized by its compact structure, typically consisting of 29 amino acids, and features a distinctive three-dimensional conformation stabilized by disulfide bonds. Its positive charge allows it to interact with negatively charged microbial membranes, leading to membrane disruption and pathogen lysis. Additionally, defensin HNP-1 has been implicated in modulating immune responses, promoting wound healing, and influencing inflammation. The peptide is also known for its ability to attract immune cells to sites of infection, thereby enhancing the overall immune response. Due to its significant role in host defense, HNP-1 is of interest in therapeutic research, particularly in developing new antimicrobial agents and understanding immune system functions.

Formula: C₁₅₀H₂₂₂N₄₄O₃₈S₆

Synonyms:

• H-Ala-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys-OH (Disulfide bonds between Cys2 and Cys30/Cys4 and Cys19/ Cys9 and Cys29)
• L-Cysteine,L-alanyl-L-cysteinyl-L-tyrosyl-L-cysteinyl-L-arginyl-L-isoleucyl-L-prolyl-L-alanyl-L-cysteinyl-L-isoleucyl-L-alanylglycyl-L-a-glutamyl-L-arginyl-L-arginyl-L-tyrosylglycyl-L-threonyl-L-cysteinyl-L-isoleucyl-L-tyrosyl-L-glutaminylglycyl-L-arginyl
• DefensinNP 1 (human)
• 1: PN: US20060057654 SEQID: 1 claimed protein
• Defensin HNP 1
• Hnp 1
• Human neutrophil peptide 1
• NP 1 (human)
• Defensin HNP-1 (human)

Defensin HNP-1 human

CAS: 99287-08-8

Defensin HNP-1, a human neutrophil peptide, regulates early atherosclerosis and endothelial dysfunction.

Formula: C₁₅₀H₂₂₈N₄₄O₃₈S₆

Color and Shape: Solid

Molecular weight: 3448.1

Ref: TM-T41135

Defensin HNP-1

CAS: 99287-08-8

Formula: C₁₅₀H₂₂₂N₄₄O₃₈S₆

Molecular weight: 3442.02

Ref: 7W-GL0441

α-Defensin-1, human

CAS: 99287-08-8

α-Defensin-1, human is a peptide that belongs to the class of defensins. It is an activator of ion channels and a ligand for receptors. α-Defensin-1, human also inhibits protein interactions with the receptor. It is purified to high purity and has CAS number 99287-08-8. This product can be used as a research tool in cell biology and pharmacology.

Formula: C₁₅₀H₂₂₂N₄₄O₃₈S₆

Purity: Min. 95%

Molecular weight: 3,442 g/mol

Ref: 3D-PDF-4271-S

Defensin hnp-1 human

CAS: 99287-08-8

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Formula: C₁₅₀H₂₂₂N₄₄O₃₈S₆

Purity: Min. 95%

Molecular weight: 3,442.03 g/mol

Ref: 3D-ZDA28708