CAS 99287-12-4

1-[1-(3-isothiocyanatophenyl)cyclohexyl]piperidine methanesulfonate

Description:

1-[1-(3-Isothiocyanatophenyl)cyclohexyl]piperidine methanesulfonate, with the CAS number 99287-12-4, is a chemical compound that features a piperidine ring substituted with a cyclohexyl group and a phenyl group containing an isothiocyanate functional group. This compound is characterized by its unique structural features, which contribute to its potential biological activity. The presence of the isothiocyanate group suggests reactivity that may be relevant in medicinal chemistry, particularly in the development of compounds with anticancer or antimicrobial properties. The methanesulfonate moiety enhances the solubility of the compound in polar solvents, which can be advantageous for various applications, including biological assays. Additionally, the compound's structural complexity may influence its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion. Overall, this compound represents a class of molecules that may be of interest in research settings, particularly in the fields of organic synthesis and drug discovery.

Formula: C₁₉H₂₈N₂O₃S₂

InChI: InChI=1/C18H24N2S.CH4O3S/c21-15-19-17-9-7-8-16(14-17)18(10-3-1-4-11-18)20-12-5-2-6-13-20;1-5(2,3)4/h7-9,14H,1-6,10-13H2;1H3,(H,2,3,4)

SMILES: C1CCC(CC1)(c1cccc(c1)N=C=S)N1CCCCC1.CS(=O)(=O)O

Synonyms:

• 1-[1-(3-Isothiocyanatophenyl)cyclohexyl]piperidine methanesulfonate (1:1)
• Piperidine, 1-[1-(3-Isothiocyanatophenyl)Cyclohexyl]-, Methanesulfonate (1:1)

Metaphit methanesulfonate salt

CAS: 99287-12-4

Formula: C₁₈H₂₄N₂S·CH₃SO₃H

Molecular weight: 396.57

Ref: 7W-GL5594

Metaphit Methanesulfonate Salt

Controlled Product

CAS: 99287-12-4

Stability Hygroscopic
Applications Metaphit Methanesulfonate Salt is an irreversible, non-competitive antagonist at the PCP site on the NMDA receptor, and an irreversible, competitive antagonist at sigma receptors. Methanesulfonate Salt
References Bluth, L.S., et al.: Eur. J. Pharmacol., 161, 273 (1989), Zimanyi, I., et al.: Synapse, 3, 239 (1989)

Formula: C₁₈H₂₄N₂S·CH₄O₃S

Color and Shape: Neat

Molecular weight: 396.57

Ref: TR-M258810

Metaphit methylsulfate

CAS: 99287-12-4

Metaphit methylsulfate is a specific PCP antagonist and an acylating agent for the [3H] phencyclidine binding site in rat brain homogenate. It inhibits PCP-induced motor activity through a presynaptic mechanism.

Formula: C₁₉H₂₈N₂O₃S₂

Color and Shape: Solid

Molecular weight: 396.567

Ref: TM-T204740