CAS 99291-24-4

Levodropropizine

Description:

Levodropropizine is a chemical compound primarily used as a cough suppressant. It is classified as a non-opioid antitussive agent, which means it alleviates coughing without the addictive properties associated with opioid medications. The substance works by acting on the cough center in the brain, reducing the urge to cough. Levodropropizine is known for its peripheral action, which minimizes central nervous system side effects, making it a preferred choice for patients who may be sensitive to such effects. The compound is typically administered in oral form and is often found in various cough syrups and formulations. Its safety profile is generally favorable, with a low incidence of adverse effects, although some individuals may experience mild gastrointestinal disturbances. As with any medication, it is important to use levodropropizine under the guidance of a healthcare professional, particularly in populations such as children or those with pre-existing health conditions. Overall, levodropropizine serves as an effective option for managing cough symptoms in various clinical settings.

Formula: C₁₃H₂₀N₂O₂

InChI: InChI=1/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2/t13-/m0/s1

SMILES: c1ccc(cc1)N1CCN(CC1)C[C@@H](CO)O

Synonyms:

• (S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
• (2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
• (2R)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol

LEVODROPROPIZINE IMPURITY A CRS

CAS: 99291-24-4

LEVODROPROPIZINE IMPURITY A CRS

Color and Shape: Added

Ref: 41-L0420002

(+)-Dropropizine

CAS: 99291-24-4

(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex.

Formula: C₁₃H₂₀N₂O₂

Purity: >99.99%

Color and Shape: White Or Off White Crystalline Powder

Molecular weight: 236.31

Ref: TM-T0217L

Levodropropizine EP Impurity A (Dextrodropropizine)

CAS: 99291-24-4

Formula: C₁₃H₂₀N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 236.32

Ref: 4Z-D-446

(R)-(+)-Dropropizine

Controlled Product

CAS: 99291-24-4

Applications R-Form of Dropropizine (D681495). (R)-(+)-Dropropizine is a cough suppressive phenylpiperazine derivative. (R)-(+)-Dropropizine is an antitussive and central sedative therapeutic agent.
References Salunkhe, M.M. et al.: Enz. Microb. Technol., 28, 333 (2001); Giani, R. et al.: Arzneim.-Forsch., 38, 1139 (1988);

Formula: C₁₃H₂₀N₂O₂

Color and Shape: Neat

Molecular weight: 236.31

Ref: TR-D681505

(R)-(+)-Dropropizine-d4

Controlled Product

CAS: 99291-24-4

Formula: C₁₃D₄H₁₆N₂O₂

Color and Shape: Neat

Molecular weight: 240.335

Ref: TR-D681507

(2R)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol

CAS: 99291-24-4

(2R)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol is a chemical compound that has been shown to suppress chronic cough in an animal model. It acts by inhibiting the release of acetylcholine from nerve endings, which reduces the reflex contraction of smooth muscle in the airway. (2R)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol also has antiinflammatory activity and can be used for the treatment of infectious diseases caused by natural compounds such as chromatographic analysis and chemiluminescence method. The rate constant for this compound is 0.0067 min(-1).

Formula: C₁₃H₂₀N₂O₂

Purity: Min. 95%

Molecular weight: 236.31 g/mol

Ref: 3D-FP180030

Dropropizine R-Isomer

CAS: 99291-24-4

Formula: C₁₃H₂₀N₂O₂

Molecular weight: 236.3

Ref: ST-EA-CP-D41004

Levodropropizine EP Impurity A

CAS: 99291-24-4

Formula: C₁₃H₂₀N₂O₂

Molecular weight: 236.3

Ref: ST-EA-CP-L38001