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CAS 99294-94-7

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Teriparatide acetate hydrate

Description:
Teriparatide acetate hydrate is a synthetic peptide that mimics the action of parathyroid hormone (PTH) and is primarily used in the treatment of osteoporosis. It is characterized by its ability to stimulate bone formation by promoting osteoblast activity, making it particularly effective in increasing bone density and reducing the risk of fractures in postmenopausal women and individuals with certain types of osteoporosis. The substance is typically administered via subcutaneous injection and is known for its relatively short half-life, necessitating daily dosing. Teriparatide acetate hydrate is a white to off-white powder that is soluble in water, and its formulation includes acetate as a counterion, which helps stabilize the peptide. The compound's molecular structure consists of 34 amino acids, and it is classified as a biological drug due to its peptide nature. As with any medication, it is essential to consider potential side effects, contraindications, and the need for monitoring during treatment.
Formula:C2H4O2·xH2O·xUnspecified
InChI:InChI=1/C181H291N55O51S2/c1-21-96(18)146(236-160(267)114(48-53-141(250)251)212-174(281)132(84-239)232-177(284)143(93(12)13)233-147(254)103(185)82-237)178(285)216-111(45-50-134(187)241)155(262)219-119(65-90(6)7)163(270)213-116(55-62-289-20)158(265)224-124(71-100-79-196-86-203-100)167(274)226-126(73-135(188)242)169(276)217-117(63-88(2)3)148(255)201-81-138(245)205-105(39-27-30-56-182)149(256)223-123(70-99-78-195-85-202-99)166(273)221-121(67-92(10)11)164(271)225-128(75-137(190)244)171(278)231-131(83-238)173(280)214-115(54-61-288-19)157(264)210-112(46-51-139(246)247)153(260)208-109(43-34-60-199-181(193)194)159(266)234-144(94(14)15)175(282)215-113(47-52-140(248)249)156(263)222-122(69-98-77-200-104-38-26-25-37-102(98)104)165(272)220-120(66-91(8)9)161(268)209-108(42-33-59-198-180(191)192)151(258)206-106(40-28-31-57-183)150(257)207-107(41-29-32-58-184)152(259)218-118(64-89(4)5)162(269)211-110(44-49-133(186)240)154(261)228-129(76-142(252)253)172(279)235-145(95(16)17)176(283)229-125(72-101-80-197-87-204-101)168(275)227-127(74-136(189)243)170(277)230-130(179(286)287)68-97-35-23-22-24-36-97/h22-26,35-38,77-80,85-96,103,105-132,143-146,200,237-239H,21,27-34,39-76,81-84,182-185H2,1-20H3,(H2,186,240)(H2,187,241)(H2,188,242)(H2,189,243)(H2,190,244)(H,195,202)(H,196,203)(H,197,204)(H,201,255)(H,205,245)(H,206,258)(H,207,257)(H,208,260)(H,209,268)(H,210,264)(H,211,269)(H,212,281)(H,213,270)(H,214,280)(H,215,282)(H,216,285)(H,217,276)(H,218,259)(H,219,262)(H,220,272)(H,221,273)(H,222,263)(H,223,256)(H,224,265)(H,225,271)(H,226,274)(H,227,275)(H,228,261)(H,229,283)(H,230,277)(H,231,278)(H,232,284)(H,233,254)(H,234,266)(H,235,279)(H,236,267)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,286,287)(H4,191,192,198)(H4,193,194,199)
SMILES:CCC(C)C(C(=NC(CCC(=N)O)C(=NC(CC(C)C)C(=NC(CCSC)C(=NC(Cc1cnc[nH]1)C(=NC(CC(=N)O)C(=NC(CC(C)C)C(=NCC(=NC(CCCCN)C(=NC(Cc1cnc[nH]1)C(=NC(CC(C)C)C(=NC(CC(=N)O)C(=NC(CO)C(=NC(CCSC)C(=NC(CCC(=O)O)C(=NC(CCCNC(=N)N)C(=NC(C(C)C)C(=NC(CCC(=O)O)C(=NC(Cc1c[nH]c2ccccc12)C(=NC(CC(C)C)C(=NC(CCCNC(=N)N)C(=NC(CCCCN)C(=NC(CCCCN)C(=NC(CC(C)C)C(=NC(CCC(=N)O)C(=NC(CC(=O)O)C(=NC(C(C)C)C(=NC(Cc1cnc[nH]1)C(=NC(CC(=N)O)C(=NC(Cc1ccccc1)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C(C(CCC(=O)O)N=C(C(CO)N=C(C(C(C)C)N=C(C(CO)N)O)O)O)O
Synonyms:
  • <span class="text-smallcaps">L</smallcap>-Phenylalanine, <smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-leucylglycyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-tryptophyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-α-aspartyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-asparaginyl-, acetate (salt), hydrate
  • <span class="text-smallcaps">L</smallcap>-Phenylalanine, <smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-leucylglycyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-tryptophyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-α-aspartyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-asparaginyl-, acetate, hydrate (1:?:?)
  • Forteo
  • L-Phenylalanine, L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-, acetate (salt)
  • L-Phenylalanine, L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-, acetate (salt) hydrate
  • L-Seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-L-phenylalanine acetate (salt) hydrate
  • Parathar
  • Parathar acetate
  • Teribone
  • Teriparatide Acetate
  • See more synonyms
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Found 2 products.