CAS 99300-67-1

3-Pyridinesulfonamide,4-[(4-hydroxy-3-methylphenyl)amino]-N-[[(1-methylethyl)amino]carbonyl]-

Description:

3-Pyridinesulfonamide, 4-[(4-hydroxy-3-methylphenyl)amino]-N-[[(1-methylethyl)amino]carbonyl]- is a chemical compound characterized by its complex structure, which includes a pyridine ring, a sulfonamide group, and an amine functionality. This compound typically exhibits properties associated with sulfonamides, such as potential antibacterial activity, due to the presence of the sulfonamide moiety. The presence of the hydroxy and methyl groups on the aromatic ring may influence its solubility and reactivity, while the isopropyl group attached to the amine can enhance lipophilicity. The compound's molecular structure suggests it may participate in hydrogen bonding and other intermolecular interactions, which can affect its biological activity and pharmacokinetics. Additionally, the specific arrangement of functional groups may confer unique properties, making it of interest in medicinal chemistry and drug development. As with many organic compounds, its stability, reactivity, and potential applications would depend on the specific conditions under which it is used.

Formula: C₁₆H₂₀N₄O₄S

Synonyms:

• Ac 3535
• 4-((4-hydroxy-3-methylphenyl)amino)-N-(isopropylcarbamoyl)pyridine-3-sulfonamide
• 3-Pyridinesulfonamide, 4-[(4-hydroxy-3-methylphenyl)amino]-N-[[(1-methylethyl)amino]carbonyl]-
• 1-[4-(4-hydroxy-3-methylanilino)pyridin-3-yl]sulfonyl-3-propan-2-ylurea
• Torasemide Impurity 47
• Torasemide M3
• 4-[(4-Hydroxy-3-Methylphenyl)aMino]-N-[[(1-Methylethyl)aMino]carbonyl]-3-pyridinesulfonaMide
• Torsemide 4-Hydroxy Impurity
• 4'-Hydroxy TorseMide

Torasemide (Torsemide) Impurity 12

CAS: 99300-67-1

Formula: C₁₆H₂₀N₄O₄S

Molecular weight: 364.42

Ref: 4Z-T-1122

4’-Hydroxy Torsemide

Controlled Product

CAS: 99300-67-1

Applications A metabolite of Torsemide (T548750).
References Besenfelder, E., et al.: J. Pharm. Biomed. Anal., 5, 259 (1987), Vormfelde, S., et al.: Clin. Pharmacol. Ther., 76, 557 (2004),

Formula: C₁₆H₂₀N₄O₄S

Color and Shape: Neat

Molecular weight: 364.419

Ref: TR-H969985

4'-Hydroxy torsemide

CAS: 99300-67-1

4'-Hydroxy torsemide is a potent diuretic that has been shown to increase renal sodium excretion and inhibit the reabsorption of chloride ions. It has also been shown to have a beneficial effect in oedematous patients with congestive heart failure. 4'-Hydroxy torsemide inhibits the activity of aminopyridine, which is an enzyme involved in the synthesis of cGMP. This inhibition causes an increase in intracellular levels of cGMP, which leads to vasodilation and decreased peripheral vascular resistance. The drug has also been found to be effective against cirrhosis, although it does not affect potassium levels or blood pressure.

Formula: C₁₆H₂₀N₄O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 364.42 g/mol

Ref: 3D-FH24146

4’-Hydroxy Torsemide

CAS: 99300-67-1

Formula: C₁₆H₂₀N₄O₄S

Molecular weight: 364.42

Ref: ST-EA-CP-T27019