CAS 994-30-9

Triethylsilyl chloride

Description:

Triethylsilyl chloride, with the CAS number 994-30-9, is an organosilicon compound characterized by the presence of a silicon atom bonded to three ethyl groups and one chlorine atom. It is typically a colorless to pale yellow liquid with a pungent odor. This compound is known for its reactivity, particularly as a silylating agent in organic synthesis, where it can introduce triethylsilyl groups into various substrates, enhancing their stability and solubility. Triethylsilyl chloride is sensitive to moisture and can hydrolyze in the presence of water, releasing hydrochloric acid and forming triethylsilanol. It is commonly used in the preparation of silyl ethers and in the protection of alcohols and amines during chemical reactions. Due to its reactivity, it should be handled with care, using appropriate safety measures to avoid skin and eye contact, as well as inhalation of vapors. Overall, triethylsilyl chloride is a valuable reagent in synthetic organic chemistry, particularly in the field of organosilicon chemistry.

Formula: C₆H₁₅ClSi

InChI: InChI=1S/C6H15ClSi/c1-4-8(7,5-2)6-3/h4-6H2,1-3H3

InChI key: InChIKey=DCFKHNIGBAHNSS-UHFFFAOYSA-N

SMILES: [Si](CC)(CC)(CC)Cl

Synonyms:

• Chlorotriethylsilane
• Chlortriethylsilan
• Clorotrietilsilano
• Silane, chlorotriethyl-
• TESCl
• Tesc
• Triethylsilyl chloride
• Triethylchlorosilane

Chlorotriethylsilane

CAS: 994-30-9

Formula: C₆H₁₅ClSi

Purity: >97.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 150.72

Ref: 3B-T0589

Chlorotriethylsilane, 98+%

CAS: 994-30-9

Chlorotriethylsilane is used in laboratory chemicals. It is used for preparing silylating agent and acts as a catalyst for lewis acid. It is used for executing chemical reactions for silicon oil, silicon resin and polysiloxane. It is also used for eradicating robe agent, and used as protective agent

Formula: C₆H₁₅ClSi

Purity: 98+%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 150.72

Ref: 02-A15547

Triethylchlorosilane, 99%

CAS: 994-30-9

Triethylchlorosilane, 99%

Formula: (C₂H₅)₃SiCl

Purity: 99%

Color and Shape: colorless liq.

Molecular weight: 150.73

Ref: 08-93-1463

Triethylchlorosilane

CAS: 994-30-9

Formula: C₆H₁₅ClSi

Purity: 97%

Color and Shape: Liquid

Molecular weight: 150.7218

Ref: IN-DA0035QQ

Chlorotriethylsilane

CAS: 994-30-9

Chlorotriethylsilane

Formula: C₆H₁₅ClSi

Purity: ≥95%

Color and Shape: clear colourless liquid

Molecular weight: 150.72g/mol

Ref: 54-OR40296

Chlorotriethylsilane

CAS: 994-30-9

Formula: C₆H₁₅ClSi

Purity: ≥ 98.0%

Color and Shape: Clear, colourless to light-yellow liquid

Molecular weight: 150.73

Ref: 7W-GK2151

TRIETHYLCHLOROSILANE

CAS: 994-30-9

Trialkylsilyl Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
Triethylchlorosilane; Chlorotriethylsilane; TES-Cl
Stability of ethers intermediate between TMS and TBS ethersGood for 1°, 2°, 3° alcoholsCan be cleaved in presence of TBS, TIPS and TBDPS ethersUsed primarily for the protection of alcoholsCan be used to protect amines and carboxylic acidsSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

Formula: C₆H₁₅ClSi

Purity: 97%

Color and Shape: Liquid

Molecular weight: 150.72

Ref: 3H-SIT8250.0

Chlorotriethylsilane

Controlled Product

CAS: 994-30-9

Stability Moisture Sensitive
Applications Chlorotriethylsilane is used in the preparation of potent silylating agent and lewis acid catalyst. Chlorotriethylsilane derivatived ethers have been shown to be more stable towards hydrolysis than are trimethyl ethers.
E0
References Alvisi, C. et al.: J. Org. Chem., 63, 1330 (1998): Higashiya, S. et al.: J. Org. Chem., 69, 6326 (2004); Hicks, J.D. et al.: Org. Lett., 9, 5621 (2007);

Formula: C₆H₁₅ClSi

Color and Shape: Neat

Molecular weight: 150.72

Ref: TR-C421750

Chlorotriethylsilane

CAS: 994-30-9

Chlorotriethylsilane is a silylating agent that reacts with hydroxyl groups to form chloroethoxysilanes. It is used to prepare the 10-desacetyl paclitaxel intermediate, which is a precursor of paclitaxel, an anticancer drug. The reaction solution is typically prepared by mixing the reagents in a flow system and then treated with water vapor. This reaction produces hydrochloric acid as a by-product, so it must be conducted under an inert atmosphere or in a dry box. Chlorotriethylsilane also reacts with fatty acids to form chloroethoxy fatty acid esters that are used as detergents for fats and oils. Chlorotriethylsilane can react with terpenes and dibutyltin oxide to produce chlorodibutyltin compounds that are used as lubricants and antifouling agents for metal surfaces. Chlorotriethylsilane can

Formula: C₆H₁₅ClSi

Purity: Min. 95%

Color and Shape: Colorless Powder

Molecular weight: 150.72 g/mol

Ref: 3D-FC61114