CAS 99418-52-7
:isopropyl 2,2,2-trichloroacetimidate(WXG01431)
Description:
Isopropyl 2,2,2-trichloroacetimidate, with the CAS number 99418-52-7, is a chemical compound characterized by its imidate functional group and the presence of three chlorine atoms attached to the acetyl moiety. This compound is typically used as a reagent in organic synthesis, particularly in the formation of amides and other nitrogen-containing compounds. It is known for its ability to activate carboxylic acids for subsequent nucleophilic attack, making it valuable in peptide synthesis and other applications in medicinal chemistry. The presence of the isopropyl group contributes to its steric properties, influencing its reactivity and solubility in organic solvents. Isopropyl 2,2,2-trichloroacetimidate is generally handled with care due to its potential toxicity and reactivity, particularly in the presence of moisture, which can lead to hydrolysis. Proper safety measures, including the use of personal protective equipment, are essential when working with this compound in a laboratory setting.
Formula:C5H8Cl3NO
Synonyms:- Ethanimidic acid, 2,2,2-trichloro-, 1-methylethyl ester
- isopropyl 2,2,2-trichloroacetimidate
- isopropyl 2,2,2-trichloroacetimidate(WXG01431)
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