CAS 99460-76-1

(5E)-2-thioxo-5-{[4-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidin-4-one

Description:

(5E)-2-thioxo-5-{[4-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidin-4-one is a thiazolidinone derivative characterized by its thiazolidine ring structure, which incorporates a thione functional group. This compound features a trifluoromethyl group attached to a phenyl ring, contributing to its unique electronic properties and potential biological activity. The presence of the thione group suggests that it may exhibit reactivity typical of sulfur-containing compounds, including potential interactions with biological targets. The compound's structure indicates it may possess significant lipophilicity due to the trifluoromethyl group, which can enhance its membrane permeability. Additionally, thiazolidinones are often studied for their pharmacological properties, including anti-inflammatory and antimicrobial activities. The specific stereochemistry indicated by the (5E) configuration suggests a particular spatial arrangement that could influence the compound's biological interactions and efficacy. Overall, this compound represents a class of molecules with potential applications in medicinal chemistry and drug development, warranting further investigation into its properties and effects.

Formula: C₁₁H₆F₃NOS₂

InChI: InChI=1/C11H6F3NOS2/c12-11(13,14)7-3-1-6(2-4-7)5-8-9(16)15-10(17)18-8/h1-5H,(H,15,16,17)/b8-5+

Synonyms:

• (5E)-2-sulfanyl-5-[4-(trifluoromethyl)benzylidene]-1,3-thiazol-4(5H)-one
• 4(5H)-thiazolone, 2-mercapto-5-[[4-(trifluoromethyl)phenyl]methylene]-, (5E)-

(5E)-2-mercapto-5-[4-(trifluoromethyl)benzylidene]-1,3-thiazol-4(5H)-one

CAS: 99460-76-1

Formula: C₁₁H₆F₃NOS₂

Purity: 95.0%

Molecular weight: 289.29

Ref: 10-F307882