CAS 99519-84-3
:Carboxyamidotriazole
Description:
Carboxyamidotriazole (CAI) is a chemical compound known for its potential therapeutic applications, particularly in the field of oncology. It is classified as a triazole derivative and features a carboxamide functional group, which contributes to its biological activity. CAI exhibits properties that may inhibit angiogenesis, the process by which new blood vessels form from existing ones, making it a candidate for cancer treatment by potentially restricting tumor growth. The compound is typically characterized by its moderate solubility in water and organic solvents, which can influence its bioavailability and pharmacokinetics. Additionally, CAI has been studied for its effects on various cellular pathways, including those involved in cell proliferation and apoptosis. Its mechanism of action often involves the modulation of signaling pathways, making it a subject of interest in drug development. As with many chemical substances, safety and toxicity profiles are crucial for its application in therapeutic contexts, necessitating thorough research and clinical evaluation.
Formula:C17H12Cl3N5O2
InChI:InChI=1/C17H12Cl3N5O2/c18-10-3-1-9(2-4-10)15(26)13-11(19)5-8(6-12(13)20)7-25-16(21)14(17(22)27)23-24-25/h1-6H,7,21H2,(H2,22,27)
InChI key:InChIKey=WNRZHQBJSXRYJK-UHFFFAOYSA-N
SMILES:C(=O)(C1=C(Cl)C=C(CN2C(N)=C(C(N)=O)N=N2)C=C1Cl)C3=CC=C(Cl)C=C3
Synonyms:- Carboxyamidotriazole
- L 651582
- 4-Cai
- 5-Amino-1-((3,5-dichloro-4-(4-chlorobenzoyl)phenyl)methyl)-1H-1,2,3-triazole-4-carboxamide
- Carboxyamido-triazole
- L651582
- Nsc 609974
- 1H-1,2,3-Triazole-4-carboxamide, 5-amino-1-((3,5-dichloro-4-(4-chlorobenzoyl)phenyl)methyl)-
- 5-amino-1-[3,5-dichloro-4-(4-chlorobenzoyl)benzyl]-1H-1,2,3-triazole-4-carboxamide
- 5-Amino-1-[3,5-Dichloro-4-(4-Chloro-Benzoyl)-Benzyl]-1H-[1,2,3]Triazole-4-Carboxylic Acid Amide
- CAI
- carboxyaMido-triazole(5-AMino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxaMide)
- 5-Amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1H-1,2,3-triazole-4-carboxamide
- Merck L651582 5-aMino-1-[3,5-dichloro-4-(4-chloro-benzoyl)-benzyl]-1H-[1,2,3]triazole-4-carboxylic acid aMide
- MERCK L651582
- 5-Amino-1-[3,5-dichloro-4-(4-chlorobenzoyl)benzyl]-1H-[1,2,3]triazole-4-carboxylic acid amide
- 5-amino-1-[4-(4-chlorobenzoyl)-3,5-dichlorobenzyl]-1,2,3-triazole-4-carboxamide
- 1-[3,5-Dichloro-4-(4-chlorobenzoyl)benzyl]-5-amino-1H-1,2,3-triazole-4-carboxamide
- See more synonyms
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Found 9 products.
5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
CAS:Formula:C17H12Cl3N5O2Purity:95%Color and Shape:SolidMolecular weight:424.66855-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamide
CAS:5-Amino-1-(3,5-dichloro-4-(4-chlorobenzoyl)benzyl)-1H-1,2,3-triazole-4-carboxamidePurity:95%Molecular weight:424.68g/mol5-AMINO-1-(3,5-DICHLORO-4-(4-CHLOROBENZOYL)BENZYL)-1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE
CAS:Purity:95%Molecular weight:424.6700134Carboxyamidotriazole
CAS:Controlled Product<p>Applications Carboxyamidotriazole is an orally active calcium channel blocker. Carboxyamidotriazole also exhibits inhibition of pro-inflammatory cytokines in tumor associated macrophages as potential anti-cancer mechanism.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ju, R., et al.: Euro. J. Cancer., 48, 1085 (2012); Corrado, C., et al.: Cancer. lett., 300, 205 (2011);<br></p>Formula:C17H12Cl3N5O2Color and Shape:NeatMolecular weight:424.67Carboxyamidotriazole
CAS:<p>Non-voltage dependent calcium channel; anti-tumour drug</p>Formula:C17H12Cl3N5O2Purity:Min. 95%Molecular weight:424.67 g/molCarboxyamidotriazole
CAS:<p>Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways.</p>Formula:C17H12Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:424.67
