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CAS 99540-94-0

:

Guanosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-

Description:
Guanosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-, identified by CAS number 99540-94-0, is a modified nucleoside derivative of guanosine. This compound features a deoxyribose sugar moiety, which is characteristic of DNA nucleosides, and includes a silyl protecting group that enhances its stability and solubility in organic solvents. The presence of the N-(2-methyl-1-oxopropyl) substituent indicates that it has been chemically modified to potentially improve its biological activity or to facilitate its use in synthetic applications. The silyl group serves to protect the hydroxyl group at the 3' position, which is crucial for preventing unwanted reactions during synthesis or in biological contexts. Overall, this compound is of interest in biochemical research and synthetic chemistry, particularly in the development of nucleic acid analogs and in studies involving gene expression and regulation. Its unique structural features may also influence its interaction with enzymes and other biomolecules.
Formula:C20H33N5O5Si
Synonyms:
  • 3'-O-TBDMS-2'-dG(iBu)
  • 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-
  • Guanosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-
  • 3'-O-TBDMS-N2-iBu-dG
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