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CAS 99570-78-2

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K-252b, Nocardiopsis sp.

Description:
K-252b is a natural product derived from the bacterium Nocardiopsis sp., known for its complex structure and significant biological activity. It belongs to the class of compounds known as indolocarbazoles, which are characterized by a fused indole and carbazole moiety. K-252b exhibits a range of pharmacological properties, including potent inhibition of protein kinases, which makes it a subject of interest in cancer research and other therapeutic areas. Its mechanism of action involves the modulation of various signaling pathways, contributing to its potential as an anticancer agent. Additionally, K-252b has shown neuroprotective effects, suggesting possible applications in neurodegenerative diseases. The compound is typically studied in the context of its biosynthetic pathways and potential synthetic analogs, which may enhance its efficacy or reduce toxicity. As with many natural products, the complexity of its structure poses challenges for synthesis and characterization, making it a valuable target for both natural product chemistry and medicinal chemistry research.
Formula:C26H19N3O5
Synonyms:
  • K252b
  • K-252B, NOCARDIOPSIS SPECIES
  • 9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, (9S,10R,12R)-
  • K-252B
  • Antibiotic K 252b
  • k-252b solution
  • K-252B, NOCARDIOPSIS SP
  • (9R,10S,12S)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid
  • PROTEIN KINASE INHIBITOR K-252B
  • K252b Antibiotic K 252b KT 5556
  • See more synonyms
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Found 4 products.