CAS 99592-32-2

Sertaconazole

Description:

Sertaconazole is an antifungal agent primarily used in the treatment of superficial fungal infections, particularly those caused by dermatophytes and yeasts. It belongs to the class of imidazole derivatives and exhibits broad-spectrum antifungal activity. Sertaconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. The compound is typically formulated as a topical cream or solution for direct application to affected areas. Sertaconazole is characterized by its relatively low solubility in water, which enhances its efficacy when applied topically, as it allows for prolonged contact with the skin. Additionally, it has anti-inflammatory properties, which can help alleviate associated symptoms such as redness and itching. The chemical structure of sertaconazole includes a benzothiazole moiety, contributing to its pharmacological profile. As with any medication, potential side effects may include local irritation or allergic reactions, and it is important to use it under medical supervision to ensure safety and effectiveness.

Formula: C₂₀H₁₅Cl₃N₂OS

InChI: InChI=1S/C20H15Cl3N2OS/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22/h1-8,11-12,19H,9-10H2

InChI key: InChIKey=JLGKQTAYUIMGRK-UHFFFAOYSA-N

SMILES: C(OC(CN1C=CN=C1)C2=C(Cl)C=C(Cl)C=C2)C=3C=4C(SC3)=C(Cl)C=CC4

Synonyms:

• FI 7045
• 1H-Imidazole, 1-[2-[(7-chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-
• 1-[2-[(7-Chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
• Sertaconazole
• 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (1:1)
• 7-Cloro-3-(1-(2,4-diclorofenil)-2-(1H-imidazol-1-il)etoxi-metil)benzo(b)tiofeno
• UNII-72W71I16EG
• (+-)-1-(2,4-Dichloro-beta-((7-chlorobenzo(b)thien-3-yl)methoxy)phenethyl)imidazole
• Sertaconazolum [Latin]
• 7-Chloro-3-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy-methyl)benzo(b)thiophene
• BRN 5385663
• Sertaconazol
• Sertaconazole [INN]
• Sertaconazolum
• 7-Cloro-3-(1-(2,4-diclorofenil)-2-(1H-imidazol-1-il)etoxi-metil)benzo(b)tiofeno [Spanish]

1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

CAS: 99592-32-2

Formula: C₂₀H₁₅Cl₃N₂OS

Purity: 95%

Color and Shape: Solid

Molecular weight: 437.7699

Ref: IN-DA0064WI

Sertaconazole

CAS: 99592-32-2

Sertaconazole

Purity: ≥95%

Molecular weight: 437.77g/mol

Ref: 54-BUP10418

Sertaconazole

CAS: 99592-32-2

Formula: C₂₀H₁₅Cl₃N₂OS

Molecular weight: 437.77

Ref: 7W-GP3771

Sertaconazole-d6

CAS: 99592-32-2

Formula: C₂₀H₉D₆Cl₃N₂OS

Molecular weight: 443.80

Ref: 4Z-S-062005

Sertaconazole

CAS: 99592-32-2

Sertaconazole is a broad-spectrum antifungal.

Formula: C₂₀H₁₅Cl₃N₂OS

Purity: 99.483%

Color and Shape: Solid

Molecular weight: 437.77

Ref: TM-T50005

Sertaconazole nitrate

CAS: 99592-32-2

Sertaconazole nitrate is a chloride compound that falls under the category of research chemicals and intermediates. It is commonly used in the production of methyl ketones, cationic compounds, and vulvovaginal candidiasis treatments. Sertaconazole nitrate exhibits potent antifungal activity against various fungi, including Trichophyton mentagrophytes. This compound works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes.

Formula: C₂₀H₁₅Cl₃N₂OS

Purity: Min. 95%

Molecular weight: 437.8 g/mol

Ref: 3D-ZDA59232