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CAS 99592-39-9

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Sertaconazole nitrate

Description:
Sertaconazole nitrate is an antifungal agent primarily used in the treatment of skin infections caused by fungi and yeast. It belongs to the class of imidazole derivatives and exhibits broad-spectrum antifungal activity. The compound works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. Sertaconazole is typically formulated as a topical cream or solution, making it suitable for localized treatment. It is characterized by its relatively low systemic absorption when applied topically, which minimizes potential side effects. The substance is known for its effectiveness against various dermatophytes, yeasts, and some gram-positive bacteria. In terms of safety, it is generally well-tolerated, though some individuals may experience localized irritation or allergic reactions. As with any medication, it is important to follow prescribed guidelines and consult healthcare professionals for appropriate use. Overall, Sertaconazole nitrate represents a valuable option in dermatological antifungal therapy.
Formula:C20H15Cl3N2OS·HNO3
InChI:InChI=1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4)
InChI key:InChIKey=HAAITRDZHUANGT-UHFFFAOYSA-N
SMILES:C(OC(CN1C=CN=C1)C2=C(Cl)C=C(Cl)C=C2)C=3C=4C(SC3)=C(Cl)C=CC4.N(=O)(=O)O
Synonyms:
  • 1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole mononitrate
  • 1-[2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole nitrate
  • 1H-Imidazole, 1-[2-[(7-chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, mononitrate
  • 1H-Imidazole, 1-[2-[(7-chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1)
  • Dermofix
  • Dermovit
  • Ertaczo
  • Fi 7056
  • Sertaconazole mononitrate
  • Zalain
  • Sertaconazole nitrate
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Found 10 products.