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CAS 99658-03-4

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corticotropin releasing factor*antagonist

Description:
Corticotropin-releasing factor (CRF) antagonist, identified by the CAS number 99658-03-4, is a synthetic peptide that plays a significant role in modulating the hypothalamic-pituitary-adrenal (HPA) axis. This substance acts by inhibiting the action of corticotropin-releasing factor, a key hormone involved in stress response and anxiety regulation. The antagonist's primary characteristics include its ability to bind to CRF receptors, thereby blocking the physiological effects of CRF, which can lead to potential therapeutic applications in treating stress-related disorders, anxiety, and depression. The compound is typically studied in pharmacological research for its effects on behavior and neuroendocrine function. Its structure and activity are crucial for understanding its mechanism of action and potential side effects. As a research chemical, it is primarily used in laboratory settings to explore the pathways of stress response and the development of new therapeutic agents targeting the HPA axis.
Formula:C166H273N45O54S2
Synonyms:
  • a-Corticotropin-Releasing Factor 9-41, Helical
  • Alpha-Helical Crf (9-41)
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