CAS 997-68-2

Saccharopine

Description:

Saccharopine is an amino acid derivative that plays a significant role in the metabolism of lysine, an essential amino acid. It is formed through the condensation of α-aminoadipic acid and glutamate, serving as an intermediate in the lysine biosynthetic pathway, particularly in organisms that utilize the α-aminoadipate pathway. Saccharopine is characterized by its structure, which includes an amino group, a carboxyl group, and a side chain that contributes to its biochemical properties. It is soluble in water, which facilitates its participation in metabolic reactions. The compound is of interest in biochemical research, particularly in studies related to amino acid metabolism and disorders associated with lysine metabolism. Additionally, saccharopine's role in the regulation of nitrogen metabolism and its potential implications in metabolic disorders make it a subject of ongoing scientific investigation. Its CAS number, 997-68-2, is used for identification in chemical databases and regulatory contexts.

Formula: C₁₁H₂₀N₂O₆

InChI: InChI=1S/C11H20N2O6/c12-7(10(16)17)3-1-2-6-13-8(11(18)19)4-5-9(14)15/h7-8,13H,1-6,12H2,(H,14,15)(H,16,17)(H,18,19)/t7-,8-/m0/s1

InChI key: InChIKey=ZDGJAHTZVHVLOT-YUMQZZPRSA-N

SMILES: [C@@H](CCC(O)=O)(NCCCC[C@@H](C(O)=O)N)C(O)=O

Synonyms:

• <span class="text-smallcaps">L</span>-Glutamic acid, N-(5-amino-5-carboxypentyl)-, (S)-
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[(5S)-5-amino-5-carboxypentyl]-
• <span class="text-smallcaps">L</span>-Saccharopine
• Glutamic acid, N-(5-amino-5-carboxypentyl)-, <span class="text-smallcaps">L</span>-
• L-Glutamic acid, N-(5-amino-5-carboxypentyl)-, (S)-
• N-(5-amino-5-carboxypentyl)glutamic acid
• N-[(5S)-5-Amino-5-carboxypentyl]-<span class="text-smallcaps">L</span>-glutamic acid
• N-[(5S)-5-amino-5-carboxypentyl]-L-glutamic acid
• Saccharopin
• Saccharopine
• epsilon-N-(L-Glutar-2-yl)-L-lysine
• L-Saccharopine
• L-Glutamic acid, N-[(5S)-5-amino-5-carboxypentyl]-

L-Saccharopine DiHCl

CAS: 997-68-2

Formula: C₁₁H₂₀N₂O₆·2HCl

Molecular weight: 276.29 2*36.46

Ref: 4Z-S-112001

Saccharopine

CAS: 997-68-2

L-Saccharopine is a product of the breakdown of essential amino acid Lysine.

Formula: C₁₁H₂₀N₂O₆

Color and Shape: Solid

Molecular weight: 276.29

Ref: TM-T32900

L-Saccharopine-d5

CAS: 997-68-2

Formula: C₁₁H₁₅D₅N₂O₆

Molecular weight: 281.32

Ref: 4Z-S-112002

L-Saccharopine

CAS: 997-68-2

Stability Hygroscopic
Applications L-Saccharopine is a product of breakdown of essential amino acid Lysine (L468895). Saccharopine is also part of the α-aminoadipate pathway of fungal lysine biosynthesis.
References Higashino, K., et al.: Biochem. Biophys. Res. Commun., 20, 285 (1965); Johansson, E., et al.: Structure, 8, 1037 (2000)

Formula: C₁₁H₂₀N₂O₆

Color and Shape: Neat

Molecular weight: 276.29

Ref: TR-S808340

L-Saccharopine-d5

Controlled Product

CAS: 997-68-2

Formula: C₁₁H₁₅D₅N₂O₆

Color and Shape: Neat

Molecular weight: 281.32

Ref: TR-S808341

L-Saccharopine

CAS: 997-68-2

L-Saccharopine is an intermediate in the biosynthesis of lysine. It has been shown to have a role in brain function and is a potential biomarker for infectious diseases. L-Saccharopine can be found in plants, fungi, and bacteria. This enzyme is produced by dehydrogenase form saccharopine. The activity of this enzyme is measured by measuring the amount of NADH oxidized per minute at 30°C. L-Saccharopine has been shown to have a low toxicity and does not cause any side effects when administered to rats orally or intravenously at doses up to 2 g/kg body weight. L-Saccharopine has also been shown to inhibit the growth of certain types of bacteria, such as E. coli, through its inhibition of protein synthesis (in vitro).

Formula: C₁₁H₂₀N₂O₆

Purity: Min. 95%

Molecular weight: 276.29 g/mol

Ref: 3D-FS172579