CAS 99755-59-6
:Rotigotine
Description:
Rotigotine is a synthetic dopamine agonist primarily used in the treatment of Parkinson's disease and restless legs syndrome. It acts by stimulating dopamine receptors in the brain, thereby helping to alleviate symptoms associated with dopamine deficiency. The substance is characterized by its lipophilic nature, which allows for transdermal delivery via a patch formulation, providing a steady release of the medication over time. Rotigotine has a relatively short half-life, necessitating continuous administration to maintain therapeutic levels. Its chemical structure includes a chiral center, which contributes to its pharmacological activity. Common side effects may include nausea, dizziness, and somnolence, reflecting its central nervous system activity. Rotigotine is classified under the category of non-ergoline dopamine agonists, distinguishing it from other treatments in the same class. As with any medication, careful monitoring is essential to manage potential adverse effects and ensure optimal therapeutic outcomes.
Formula:C19H25NOS
InChI:InChI=1S/C19H25NOS/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21/h3-7,13,16,21H,2,8-12,14H2,1H3/t16-/m0/s1
InChI key:InChIKey=KFQYTPMOWPVWEJ-INIZCTEOSA-N
SMILES:OC1=C2C(C[C@@H](N(CCC3=CC=CS3)CCC)CC2)=CC=C1
Synonyms:- (-)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol
- (-)-N 0437
- (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
- (6S)-6-[Propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
- (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol
- (S)-(-)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
- (S)-(-)-Rotigotine
- (S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-naphth-1-ol
- (S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol
- 1-Naphthalenol 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (6S)-
- 1-Naphthalenol, 5,6,7,8-tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-
- 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (S)-
- 2-(N-n-Propyl-N-2-thienylethylamino)-5-hydroxytetralin
- 5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
- 6-(Propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol
- 6-{Propyl[2-(Thiophen-2-Yl)Ethyl]Amino}-5,6,7,8-Tetrahydronaphthalen-1-Ol
- Leganto
- N 0923
- Neupro
- See more synonyms
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Found 13 products.
Rotigotine
CAS:RotigotineFormula:C19H25NOSPurity:99.6%Color and Shape:WhiteMolecular weight:315.16569Rotigotine ((S)-6-{Propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C19H25NOSColor and Shape:White Beige PowderMolecular weight:315.16569(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
CAS:Formula:C19H25NOSPurity:99%Color and Shape:SolidMolecular weight:315.4729Rotigotine-
CAS:Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome.Formula:C19H25NOSPurity:98.08% - 99.59%Color and Shape:SolidMolecular weight:315.47(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
CAS:Controlled Product(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol is a potent and selective dopamine receptor agonist. It acts by binding to the dopamine receptors in the brain. This binding stimulates the release of dopamine and prevents it from being reabsorbed into the neurons, which in turn increases levels of extracellular dopamine in the synapse. (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol has been shown to have antidepressant effects in animal models of depression. It also has a long half life and can be administered as a transdermal patch for prolonged relief from depression symptoms.Formula:C19H25NOSPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:315.47 g/molRotigotine
CAS:Formula:C19H25NOSPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:315.48
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