CAS 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

Description:

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine, commonly referred to as DLPC, is a phospholipid that plays a significant role in cellular membranes and lipid bilayers. It is characterized by its two linoleoyl fatty acid chains, which contribute to its fluidity and flexibility, making it an important component in membrane dynamics. The molecule features a glycerol backbone, a phosphate group, and a choline head group, which imparts amphiphilic properties, allowing it to interact with both hydrophilic and hydrophobic environments. DLPC is often used in biophysical studies and drug delivery systems due to its ability to form liposomes and micelles. Its structural properties enable it to stabilize membrane structures and facilitate the incorporation of other molecules, such as drugs or proteins, enhancing their bioavailability. Additionally, DLPC is utilized in various research applications, including studies on membrane permeability and the behavior of lipid bilayers under different conditions. Overall, its unique characteristics make it a valuable substance in both biological and pharmaceutical contexts.

Formula: C₄₄H₈₀NO₈P

InChI: InChI=1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1

InChI key: InChIKey=FVXDQWZBHIXIEJ-LNDKUQBDSA-N

SMILES: [C@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCC/C=C\C/C=C\CCCCC)=O

Synonyms:

• (1,2-Dilinoleoyl)-3-lecithin
• (2R)-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
• (R-(All-Z))-(4-oxido-10-oxo-7-((1-oxooctadeca-9,12-dienyl)oxy)-3,5,9-trioxa-4-phosphaheptacosa-18,21-dienyl)trimethylammonium 4-oxide
• 1,2-Dilinoleoyl-sn-3-glycerophosphorylcholine
• 1,2-Dilinoleoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine
• 1,2-Dilinoleoyl-sn-glycerol-3-phosphocholine
• 1,2-Dilinoleoylphosphocholine
• 1-Linoleoyl-2-linoleoyl-sn-glycero-3-phosphorylcholine
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-9,12-octadecadienyl)oxy]-, hydroxide, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-9,12-octadecadienyl)oxy]-, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]oxy]-, inner salt, 4-oxide, (7R,18Z,21Z)-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadienyl]oxy]-, inner salt, 4-oxide, (7R,18Z,21Z)-
• 49: PN: WO2017201317 SEQID: 122 claimed RNA
• <span class="text-smallcaps">L</span>-(+)-α-(α′,β-Dilinoleoyl)-glycerylphosphorylcholine
• <span class="text-smallcaps">L</span>-Dilinoleoyllecithin
• <span class="text-smallcaps">L</span>-α-Dilinoleoyl phosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilinolein, <span class="text-smallcaps">L</span>-(+)-
• DLiPC
• Linolein, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide, inner salt, <span class="text-smallcaps">L</span>-(+)-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilinolein, L-(+)-

1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

CAS: 998-06-1

Formula: C₄₄H₈₀NO₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 782.0817

Ref: IN-DA003W1P

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

CAS: 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

Color and Shape: Solid

Molecular weight: 782.08g/mol

Ref: 54-BIL6001

1,2-Dilinoleoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 998-06-1

Formula: C44H80NO8P

Purity: >98%

Color and Shape: Solid

Molecular weight: 782.08

Ref: 48-37-1802

(R)-2,3-Bis((9Z,12Z)-octadeca-9,12-dienoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

CAS: 998-06-1

Purity: ≥98%

Molecular weight: 782.0969849

Ref: 10-F791285

L-Dilinoleoyllecithin

Controlled Product

CAS: 998-06-1

Formula: C₄₄H₈₀NO₈P

Color and Shape: Neat

Molecular weight: 782.082

Ref: TR-D561175

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

CAS: 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine (DLPC) is a phospholipid that is used in the treatment of insulin resistance and inflammation. DLPC is a stable molecule that exhibits intermolecular hydrogen bonding and has been shown to be effective against inflammatory diseases. DLPC has been used as a liposomal formulation for the treatment of type 2 diabetes by improving insulin sensitivity, which may be due to its ability to inhibit proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). It also binds to the receptor α, which are G protein coupled receptors present on cells involved in inflammatory responses. The binding of DLPC to these receptors leads to increased insulin sensitivity by inhibiting TNFα production.

Formula: C₄₄H₈₀NO₈P

Purity: Min. 95%

Molecular weight: 782.08 g/mol

Ref: 3D-FD42822

L-Dilinoleoyllecithin

CAS: 998-06-1

L-Dilinoleoyllecithin is phosphatidylcholine. It is a glycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site.

Formula: C₄₄H₈₀NO₈P

Color and Shape: Solid

Molecular weight: 782.08

Ref: TM-T24393