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PD-1/PD-L1

PD-1/PD-L1

PD-1/PD-L1 inhibitors are immune checkpoint inhibitors that block the interaction between the programmed cell death protein 1 (PD-1) on T cells and its ligand PD-L1 on cancer cells. This interaction normally suppresses the immune response and allows cancer cells to evade immune detection. By inhibiting PD-1/PD-L1, these inhibitors enhance the immune system's ability to recognize and destroy cancer cells, inducing apoptosis and tumor regression. PD-1/PD-L1 inhibitors are critical in immunotherapy research and cancer treatment. At CymitQuimica, we offer a range of high-quality PD-1/PD-L1 inhibitors to support your research in immuno-oncology, apoptosis, and cancer therapy.

Found 125 products of "PD-1/PD-L1"

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  • AUNP-12 acetate


    <p>AUNP-12 acetate is a polypeptide inhibitor of PD-1 that is equivalent to PD-1 and PD-2 in inhibiting lymphocyte proliferation and effector fuction, in addition</p>
    Formula:C144H230N40O50
    Purity:95.07%
    Color and Shape:Solid
    Molecular weight:3321.61
  • Durvalumab

    CAS:
    <p>Durvalumab is a humanized antibody for cancer, inhibiting PD-L1/PD-1 and CD80 interactions at very low concentrations.</p>
    Purity:SDS-PAGE:97.2%;SEC-HPLC:95.3%
    Color and Shape:Liquid
    Molecular weight:146.03 kDa
  • Ezabenlimab

    CAS:
    <p>Ezabenlimab (BI-754091) is an anti-PD-1 mAb, Kd 6 nM, blocks PD-1/PD-Ls, boosts T-cell IFN-γ, inhibits tumors in vivo.</p>
    Purity:99.1% (SDS-PAGE); 96.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.9% (SEC-HPLC)
    Color and Shape:Liquid
  • Budigalimab

    CAS:
    <p>Budigalimab (ABBV 181) is a humanized monoclonal antibody targeting PD-1 with potential antitumor activity.</p>
    Purity:97% (SDS-PAGE); 98.8% (SEC-HPLC) - 97% (SDS-PAGE); 98.8% (SEC-HPLC)
    Color and Shape:Liquid
  • Sintilimab

    CAS:
    <p>Sintilimab (IBI308), an IgG4 monoclonal antibody, blocks PD-1, enhancing T-cell anti-tumor response; treats Hodgkin's, lung, and esophageal cancers.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:144.04 kDa
  • Zimberelimab

    CAS:
    <p>Zimberelimab (GLS-010) is a humanized antibody targeting PD-1, with anticancer activity.</p>
    Purity:95%
    Color and Shape:Liquid
  • Tislelizumab

    CAS:
    <p>Tislelizumab, a PD-1 receptor monoclonal antibody, reduces Fcγ interaction and T cell clearance in advanced squamous NSCLC research.</p>
    Purity:95.07%
    Color and Shape:Liquid
  • Penpulimab

    CAS:
    <p>Penpulimab is a monoclonal antibody targeting PD-1 with antitumor activity, used in studies of pancreatic cancer.</p>
    Purity:96.8% (SEC-HPLC) - 96.8% (SEC-HPLC)
    Color and Shape:Liquid
  • Spartalizumab

    CAS:
    <p>"Spartalizumab (PDR001), a humanized IgG4 monoclonal antibody, targets PD-1 to inhibit PD-L1/L2 interactions, useful in ATC research."</p>
    Purity:SDS-PAGE:95.2%;SEC-HPLC:96.3%
    Color and Shape:Liquid
    Molecular weight:145.74 kDa
  • BMS-1001 hydrochloride

    CAS:
    <p>BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect</p>
    Formula:C35H35ClN2O7
    Purity:97.36%
    Color and Shape:Solid
    Molecular weight:631.11
  • Dostarlimab

    CAS:
    <p>Dostarlimab (TSR-042) is an immune checkpoint inhibitor targeting PD-1, blocking its interaction with its ligands PD-L1 and PD-L2.</p>
    Purity:>95%
    Color and Shape:Liquid
  • Eciskafusp alfa

    CAS:
    <p>Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specific</p>
    Purity:98%
    Color and Shape:Solid
  • PM-8002


    <p>PM-8002 is a bispecific antibody that targets PD-L1 and VEGF-A. It is applicable for research on solid tumors.</p>
    Color and Shape:Odour Liquid
  • Anti-Mouse PD-1 (LALA-PG) Antibody (RMP1-14)


    <p>Anti-MousePD-1(LALA-PG) Antibody (RMP1-14) is an IgG2a, κ antibody inhibitor derived from mice that targets and inhibits mouse PD-1.</p>
    Color and Shape:Odour Liquid
  • Anti-Mouse PD-1 Antibody (D265A) Antibody (RMP1-14)


    <p>Anti-Mouse PD-1 Antibody (D265A) is an IgG2a, κ antibody inhibitor derived from mice, specifically targeting mouse PD-1.</p>
    Color and Shape:Odour Liquid
  • Opamtistomig

    CAS:
    <p>Opamtistomig is a humanized monoclonal antibody immunoglobulin (H-γ1-scFv-L-κ) dimer targeting human programmed death-ligand 1 (PD-L1), CD274, and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). It is anticipated for use in research on various solid tumors and hematologic malignancies.</p>
    Color and Shape:Liquid
  • TQB-2858


    <p>TQB-2858 is a bifunctional fusion protein composed of an anti-PD-L1 monoclonal antibody fused with the extracellular domain of the TGF-β receptor. It exhibits high affinity for PD-L1, TGF-β1, and TGF-β3, and demonstrates a high target occupancy rate for PD-L1. TQB-2858 can be used in research on osteosarcoma and alveolar soft part sarcoma (ASPS).</p>
    Color and Shape:Odour Liquid
  • PD-1/PD-L1-IN-49


    <p>PD-1/PD-L1-IN-49 (compound 1c) is a potent inhibitor of PD-1/PD-L1 with an IC50 of 77 nM. This compound can activate Jurkat T cells and effectively block the PD-1/PD-L1 immune checkpoint.</p>
    Formula:C27H32N4O5
    Color and Shape:Solid
    Molecular weight:492.567
  • AUNP-12

    CAS:
    <p>AUNP-12, a new immune checkpoint modulator, is an inhibitor of the PD-1 pathway.</p>
    Formula:C142H226N40O48
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3261.55
  • Lon-TK


    <p>Lon-TK is a glycolysis inhibitor of LTB, linked with a linker conjugate. LTB is an intelligent responsive prodrug, comprised of Lonidamine (Lon) and a PD-L1 inhibitor (BMS-1), which are connected through a thioketal linkage. It effectively inhibits glycolytic metabolism in tumor cells and blocks the PD-1/PD-L1 immune escape pathway. Lon-TK holds potential for use in photodynamic-enhanced immunotherapy research.</p>
    Formula:C24H28Cl2N2O3S2
    Color and Shape:Solid
    Molecular weight:527.53
  • D5B


    <p>D5B is an effective and selective PD-L1 inhibitor that has been modified with DBCO. It degrades PD-L1 in 4T1 and B16-F10 tumor cells with EC50 values of 5.4 μM and 6.2 μM, respectively. D5B can block the PD-L1/PD-1 interaction and exhibits antitumor activity.</p>
    Formula:C58H66N2O12
    Color and Shape:Solid
    Molecular weight:983.15
  • PD-L1/VISTA-IN-2


    <p>PD-L1/VISTA-IN-2 (Compound S8) is an orally active dual inhibitor targeting PD-L1 and VISTA, with an IC50 of 1.4 μM for PD-L1 and a KD of 2.1 μM for VISTA. This compound can activate the tumor immune microenvironment, exerting anticancer effects.</p>
    Formula:C22H22N2O3
    Color and Shape:Solid
    Molecular weight:362.42
  • Ledostomig

    CAS:
    <p>Ledostomig is an immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody that targets human neurotensin receptor type 5 (NTS5) and programmed death-1 (PD-1). It shows potential for research in various cancer types.</p>
    Color and Shape:Liquid
  • Moflerafusp alfa

    CAS:
    <p>Moflerafusp alfa is a fusion protein that targets the human signal-regulatory protein alpha (SIRPα) variant V2 D1 domain and human programmed death-ligand 1 (PD-L1). It shows potential for research in various cancer treatments.</p>
    Color and Shape:Liquid
  • Zeluvalimab

    CAS:
    <p>Zeluvalimab (AMG-404) is a monoclonal antibody designed to target the PD-1 receptor, and is utilized in cancer research [1].</p>
    Color and Shape:Liquid
  • LTB


    <p>LTB is a prodrug formed through the conjugation of the glycolysis inhibitor (Lonidamine) and the PD1/PDL1 blocker (BMS-1) via a thioketal bond. LTB can encapsulate the photosensitizer Chlorin e6 (Ce6), constructing a co-delivery photodynamic nanoplatfform through self-assembly (LTB-6 NPs).</p>
    Formula:C53H59Cl2N3O7S2
    Color and Shape:Solid
    Molecular weight:985.09
  • Finotonlimab


    <p>Finotonlimab (SCT-I10A), a humanized IgG PD-1 monoclonal antibody, shows potential in the research of solid tumors or lymphomas [1].</p>
    Color and Shape:Odour Liquid
  • Manelimab

    CAS:
    <p>Manelimab is a monoclonal antibody that inhibits programmed death-ligand 1 ( PD-L1 ) [1] .</p>
    Color and Shape:Liquid
  • 2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc


    <p>2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc is the PD-L1 ligand-linker polymer of AUTACPD-L1degrader-3. It can be utilized in the synthesis of AUTAC.</p>
    Formula:C35H45N5O6
    Color and Shape:Solid
    Molecular weight:631.76
  • Lorigerlimab

    CAS:
    <p>Lorigerlimab (MGD019) is a bispecific IgG4 DART that blocks PD-1/CTLA-4, enhancing T-cells for mCRPC research.</p>
    Color and Shape:Liquid
  • 2-Methylbiphenyl-oxadiazole-NH-Ph-CHO

    CAS:
    <p>2-Methylbiphenyl-oxadiazole-NH-Ph-CHO functions as a PD-L1 ligand for AUTACPD-L1degrader-3. It is also applicable in the synthesis of AUTAC.</p>
    Formula:C22H17N3O2
    Color and Shape:Solid
    Molecular weight:355.39
  • Izuralimab

    CAS:
    <p>Izuralimab is a bispecific IgG1 antibody that targets both the inducible T-cell costimulator (ICOS/CD278) and PD-1 [1].</p>
    Color and Shape:Liquid
  • CAY10678

    CAS:
    <p>CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS</p>
    Formula:C23H34N4O
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:382.54
  • Lodapolimab

    CAS:
    <p>Lodapolimab (LY3300054) is an IgGλ anti- PD-1 monoclonal antibody [1] .</p>
    Color and Shape:Liquid
  • PMT-O9-1A


    <p>PMT-O9-1A is an effective PD-L1 degrader that reduces PD-L1 protein expression and exhibits cytotoxic properties. Additionally, PMT-O9-1A possesses anticancer activity.</p>
    Formula:C22H25ClN2O4
    Color and Shape:Solid
    Molecular weight:416.90
  • Opucolimab

    CAS:
    <p>Opucolimab is a human antibody targeting PD-L1, used in advanced solid tumor research and antibody-drug conjugate synthesis.</p>
    Color and Shape:Liquid
  • Betifisolimab

    CAS:
    <p>Betifisolimab (MSB-2311) is a humanized antibody targeting PD-L1 for solid tumors and blood cancer research.</p>
    Color and Shape:Liquid
  • HX009


    <p>HX009 is a bispecific antibody that targets PD1 and CD47, though its binding to CD47 is attenuated. HX009 functions by blocking PD1/CD47 and can be utilized in research related to non-Hodgkin lymphoma (NHL).</p>
    Color and Shape:Odour Liquid
  • Sudubrilimab


    <p>Sudubrilimab (HS636) is an IgG1-κ monoclonal antibody targeting PDL1, fused with TGFBR2-ECD to block PD-1/PDL1 and TGF-β in tumors.</p>
    Color and Shape:Odour Liquid
  • H-20

    CAS:
    <p>H-20 is a PD-1 agonist that reduces the required dosage of morphine for analgesia. It can be used in studies related to chronic pain.</p>
    Formula:C44H64N10O15
    Color and Shape:Solid
    Molecular weight:973.037
  • Pimivalimab

    CAS:
    <p>Pimivalimab (JTX-4014), a PD-1 inhibitor, is utilized in solid tumor research [1].</p>
    Color and Shape:Liquid
  • Human membrane-bound PD-L1 polypeptide

    CAS:
    <p>Human membrane-bound PD-L1 polypeptide serves as an antigen for inducing the production of PD-L1 antibodies [1].</p>
    Formula:C85H140N26O36S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2134.24
  • Balstilimab

    CAS:
    <p>Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 [1] .</p>
    Color and Shape:Liquid
  • Iparomlimab

    CAS:
    <p>Iparomlimab: anti-PD-1 IgG4κ antibody, targets PSB103 γ4/κ-chains, forms dimers, used in cancer research.</p>
    Color and Shape:Liquid
  • PD-1/PD-L1-IN-9

    CAS:
    <p>PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction.</p>
    Formula:C22H24N2O2
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:348.44
  • TPP-1 TFA


    <p>TPP-1 TFA is a high-affinity PD-L1 inhibitor (KD=95nM) that boosts T-cell function to curb tumor growth.</p>
    Formula:C109H151F3N34O34S2
    Color and Shape:Solid
    Molecular weight:2602.69
  • PD-1/PD-L1-IN-48


    <p>PD-1/PD-L1-IN-48 (compound HD10) is an effective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 3.1 nM. It plays a vital role in cancer research.</p>
    Color and Shape:Odour Solid
  • Human PD-L1 inhibitor I

    CAS:
    <p>Human PD-L1 inhibitor I, a peptide, blocks PD-L1/PD-1 interaction with 3.39 μM affinity.</p>
    Formula:C110H152N26O32
    Color and Shape:Solid
    Molecular weight:2350.576
  • BMSpep-57

    CAS:
    <p>BMSpep-57: Macrocyclic peptide, inhibits PD-1/PD-L1, IC50=7.68 nM, binds PD-L1 (Kd=19 nM/MST, 19.88 nM/SPR), boosts T cell IL-2 in PBMCs.</p>
    Formula:C89H126N24O19S
    Color and Shape:Solid
    Molecular weight:1868.2
  • Human PD-L1 inhibitor II

    CAS:
    <p>Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.</p>
    Formula:C103H151N25O30
    Color and Shape:Solid
    Molecular weight:2219.486
  • Anti-Mouse PD-1 Antibody (RMP1-14)


    <p>Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling. High-Quality, Low-Cost!</p>
    Purity:14.68mg/ml - >95%
    Color and Shape:Odour Liquid
  • PD-L1 inhibitory peptide

    CAS:
    <p>PD-L1inhibitory peptide is an inhibitor peptide that targets the programmed cell death ligand 1 (PD-L1). By binding to PD-L1, it lifts immune suppression and restores the anti-tumor activity of T cells. PD-L1inhibitory peptide holds promise for use in tumor research.</p>
    Formula:C96H135N21O23S
    Color and Shape:Solid
    Molecular weight:1983.29
  • Volrustomig

    CAS:
    <p>Volrustomig is a bi-engineered fragment crystallizable (Fc) domain, a monovalent bispecific IgG1 monoclonal antibody targeting the key immune checkpoint receptors PD-1 and CTLA-4. It boosts T-cell activation and antitumor immunity, making it a promising immunotherapy for various cancers. Molecular weight: 146.77 kDa.</p>
    Color and Shape:Liquid
  • Human PD-L1 inhibitor IV

    CAS:
    <p>PD-L1 inhibitor IV, a polypeptide, competitively blocks hPD-1 with a Kd of 1.38 μM, preventing hPD-1/hPD-L1 interaction.</p>
    Formula:C80H113N25O27
    Color and Shape:Solid
    Molecular weight:1856.932
  • Human PD-L1 inhibitor III

    CAS:
    <p>Human PD-L1 inhibitor III is a human PD-L1 inhibitor.</p>
    Formula:C97H155N29O29S
    Color and Shape:Solid
    Molecular weight:2223.54
  • PD-L1-IN-5


    <p>PD-L1-IN-5 (X22) is an orally active PD-L1 inhibitor with an IC50 of 785.6 nM, demonstrating antitumor activity in vivo.</p>
  • PD-1/PD-L1-IN-39


    <p>PD-1/PD-L1-IN-39 (X 14) is an orally active PD-1/PD-L1 inhibitor with an IC50 value of 15.73 nM. It exhibits strong binding affinity to human and mouse PD-L1, with KD values of 14.62 and 392 nM, respectively. PD-1/PD-L1-IN-39 also demonstrates antitumor activity.</p>
    Formula:C23H20ClFN2O3
    Molecular weight:426.11465
  • PROTAC PD-L1 degrader-1


    <p>PROTACPD-L1 degrader-1 is a CRBN-based PD-L1-PROTAC degrader with significant PD-L1 protein degradation capacity. It demonstrates strong PD-L1 degradation activity in 4T1 cells, with a DC50 of 0.609 μM. This compound is applicable to breast cancer research.</p>
  • OPBP-1


    <p>OPBP-1 is a D-peptide developed through phage display screening, molecular docking, and molecular dynamics simulations. It exhibits high stability, strong antitumor activity, and oral bioavailability. OPBP-1 selectively binds to the PD-L1 protein, significantly blocking the interaction between PD-1 and PD-L1, which helps restore and enhance T lymphocyte function while reducing the proportion of myeloid-derived suppressor cells (MDSCs), counteracting tumor-induced immune evasion. OPBP-1 is applicable for research in cancer immunotherapy.</p>
    Formula:C64H92N20O19S
    Molecular weight:1476.65683
  • Sasanlimab

    CAS:
    <p>Sasanlimab (PF-06801591), a humanized IgG4-κ antibody, selectively targets PD-1 and is primarily produced in Chinese Hamster Ovary (CHO) cells [1].</p>
    Purity:98%
    Color and Shape:Liquid
  • Camrelizumab

    CAS:
    <p>Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up</p>
    Purity:95% - 98.6%
    Color and Shape:Liquid
    Molecular weight:143.7 kDa
  • Lipustobart

    CAS:
    <p>Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplastic</p>
    Purity:98%
    Color and Shape:Liquid
  • Pidilizumab

    CAS:
    <p>Pidilizumab (CT-011), a humanized IgG1κ anti-PD-1 monoclonal antibody, serves as a DLL1 antagonist with potential applications in researching hematologic</p>
    Purity:98%
    Color and Shape:Liquid
  • Nofazinlimab

    CAS:
    <p>Nofazinlimab (CS1003) is a human anti-PD-1 IgG4 monoclonal antibody for the study of unresectable hepatocellular carcinoma (uHCC).</p>
    Purity:98.6% (SDS-PAGE); 99.7% (SEC-HPLC) - 98.6% (SDS-PAGE); 99.7% (SEC-HPLC)
    Color and Shape:Liquid
  • Latikafusp

    CAS:
    <p>Latikafusp (AMG 256) is a fusion protein that is a PD-1 blocker and IL-21R agonist with antitumor activity.</p>
    Purity:97.1% (SDS-PAGE); 97.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.4% (SEC-HPLC)
    Color and Shape:Liquid
  • Pacmilimab

    CAS:
    <p>Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors.</p>
    Purity:98.8% (SDS-PAGE); 96.3% (SEC-HPLC) - 98.8% (SDS-PAGE); 96.3% (SEC-HPLC)
    Color and Shape:Liquid
  • Acrixolimab

    CAS:
    <p>Acrixolimab is a humanized IgG4-κ monoclonal antibody that selectively targets PD-1 [1] [2].</p>
    Purity:98%
    Color and Shape:Liquid
  • Prolgolimab

    CAS:
    <p>Prolgolimab (BCD-100) is an anti-PD-1 antibody used in melanoma research.</p>
    Purity:>95%
    Color and Shape:Liquid
  • Retifanlimab

    CAS:
    <p>Retifanlimab (MGA-012) is a monoclonal antibody targeting programmed cell death protein 1 (PD-1). Retifanlimab is used in studies of Merkel cell carcinoma.</p>
    Purity:95% - 98.56% (SEC-HPLC)
    Color and Shape:Liquid
  • Anti-Mouse PD-L1 Antibody (10F.9G2)


    <p>Anti-Mouse PD-L1 Antibody (10F.9G2) is an IgG-class antibody against mouse PD-L1.</p>
    Purity:98.92% - >95% Determined by SDS-PAGE
    Color and Shape:Odour Liquid
  • Danburstotug

    CAS:
    <p>Danburstotug (IMC-001), an immunostimulant and antineoplastic [1], is a humanized IgG1-lambda monoclonal antibody targeting CD274 (PDL1, B7 homologue 1, B7H1).</p>
    Purity:98%
    Color and Shape:Liquid
  • ARB-272572 hydrochloride

    CAS:
    <p>ARB-272572 hydrochloride is a PD-L1 inhibitor that inhibits PD-1/PD-L1 cell signaling by inducing PD-L1 protein homology interactions.</p>
    Formula:C32H36N6O4·xClH
    Purity:99.38%
    Color and Shape:Soild
    Molecular weight:568.68(Free base)
  • IMMH 010 maleate

    CAS:
    <p>IMMH 010 maleate (YPD-30 maleate) is a programmed cell death ligand 1 inhibitor used in the study of neurological disorders and advanced malignant solid tumors.</p>
    Formula:C36H36BrClN2O9
    Color and Shape:Soild
    Molecular weight:756.04
  • LP23


    <p>LP23, a non-arylmethylamine PD-1/PD-L1 inhibitor (IC 50: 16.7 nM), exhibits anti-tumor activity through the restoration of immune cell function in HepG2/Jurkat</p>
    Formula:C27H27N3O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:505.59
  • (D)-PPA 1 TFA


    <p>(D)-PPA 1 TFA is a hydrolysis-resistant D-peptide antagonist and a potent PD-1/PD-L1 inhibitor, exhibiting an affinity for PD-1 of 0.51 μM and demonstrating</p>
    Formula:C72H99F3N20O23
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1669.67
  • PD-1/PD-L1-IN-31


    <p>PD-1/PD-L1-IN-31 is a potent inhibitor of PD-1/PD-L1 (IC50=2.2 nM) that enhances IFN-γ secretion and activates the immune response of peripheral blood</p>
    Formula:C24H24ClFN2O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:442.91
  • PD-1/PD-L1-IN-50


    <p>Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.</p>
    Color and Shape:Odour Solid
  • PD-1/PD-L1-IN-51


    <p>PD-1/PD-L1-IN-51 (Compound III-4) is an inhibitor of PD-1/PD-L1 (IC50: hPD-L1 at 2.9 nM). It binds directly to PD-L1, blocking the interaction between PD-1 and PD-L1, and enhancing the release of IFN-γ. Additionally, PD-1/PD-L1-IN-51 exhibits antitumor activity.</p>
    Color and Shape:Odour Solid
  • PD-1/PD-L1-IN-32


    <p>PD-1/PD-L1-IN-32 (compound A56) is a potent inhibitor of PD-1/PD-L1, displaying pronounced anticancer activity with an IC50 value of 2.4 nM.</p>
    Purity:98%
    Color and Shape:Odour Solid
  • PD-1/PD-L1-IN-52


    <p>PD-1/PD-L1-IN-52 (Compound Ⅲ-5) is an orally active inhibitor of PD-1/PD-L1 interaction, exhibiting an IC50 of 109.9 nM. It demonstrates antitumor activity in a C57BL/6 mouse model of MC38 colon carcinoma cells expressing human PD-1, achieving a tumor growth inhibition (TGI) rate of 49.6%.</p>
    Color and Shape:Odour Solid
  • Sotiburafusp alfa

    CAS:
    <p>Sotiburafusp alfa is a humanized bispecific fusion protein comprising a VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) connected</p>
    Purity:98%
    Color and Shape:Solid
  • N-deacetylated BMS-202

    CAS:
    <p>N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interaction with potential anticancer activity for cancer research.</p>
    Formula:C23H27N3O2
    Purity:98.13% - 98.13%
    Color and Shape:Solid
    Molecular weight:377.48
  • BMS-8

    CAS:
    <p>BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.</p>
    Formula:C27H28BrNO3
    Purity:98.88%
    Color and Shape:Solid
    Molecular weight:494.42
  • BMS-1166

    CAS:
    <p>BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.</p>
    Formula:C36H33ClN2O7
    Purity:99.22%
    Color and Shape:Solid
    Molecular weight:641.11
  • Nivolumab

    CAS:
    <p>Nivolumab is a monoclonal antibody, a humanized IgG4 antibody to PD-1. Nivolumab has antitumor activity. Cost-effective and quality-assured.</p>
    Purity:98% - 98%
    Color and Shape:Liquid
    Molecular weight:146 kDa
  • Pembrolizumab

    CAS:
    <p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>
    Purity:95% - 99.70%
    Color and Shape:Liquid
    Molecular weight:149 kDa
  • BMS-1001

    CAS:
    <p>BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).</p>
    Formula:C35H34N2O7
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:594.7
  • Avelumab

    CAS:
    <p>Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.</p>
    Purity:95% - 97.17% (SDS-PAGE)
    Color and Shape:Liquid
    Molecular weight:143.8 kDa
  • ARB-272572

    CAS:
    <p>ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.</p>
    Formula:C32H36N6O4
    Purity:97.36% - 98.07%
    Color and Shape:Solid
    Molecular weight:568.67
  • Socazolimab

    CAS:
    <p>Socazolimab (ZKAB001) is a monoclonal antibody targeting PD-L1 with antitumor activity, used in studies of recurrent or metastatic cervical cancer.</p>
    Purity:95%
    Color and Shape:Liquid
  • Envafolimab

    CAS:
    <p>Envafolimab (ASC 22) is a humanized antibody targeting PD-L1, with anticancer activity, blocking the PD-L1 and PD-1 interaction.</p>
    Purity:95%
    Color and Shape:Liquid
  • BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride

    CAS:
    <p>BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (</p>
    Formula:C41H45Cl3N4O5
    Purity:98.94%
    Color and Shape:Soild
    Molecular weight:780.18
  • Ivonescimab

    CAS:
    <p>Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, NSCLC).</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Acasunlimab

    CAS:
    <p>Acasunlimab (GEN1046) is a bsAb that targets PD-L1 and 4-1BB, boosting T/NK cells and blocking PD-1/PD-L1 in cancer research.</p>
    Color and Shape:Liquid
  • Reozalimab

    CAS:
    <p>Reozalimab (LY3434172) is a bispecific monoclonal antibody targeting PD-1/PD-L1, antitumour and enhances T-cell activation in vitro.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Peresolimab

    CAS:
    <p>Peresolimab is a humanized antibody targeting PD-1, potentially stimulating immune inhibitory pathways for autoimmune disease research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Visugromab

    CAS:
    <p>Visugromab (CTL-002) is a monoclonal antibody that targets and neutralises GDF-15.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Gilvetmab

    CAS:
    <p>Gilvetmab is a caninized anti-PD-1 antibody approved for veterinary use, researched for stage I-III mast cell tumors and stage II-III melanoma in dogs.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Rulonilimab

    CAS:
    <p>Rulonilimab, a human IgG1 monoclonal antibody, inhibits PD-1 to enhance immune response and exhibit anti-tumor effects.</p>
    Color and Shape:Liquid
  • Rosnilimab

    CAS:
    <p>Rosnilimab is a PD-1 agonist that inhibits T cell proliferation and depletes T cells, enabling research into inflammatory diseases.</p>
    Purity:95% - 95%
    Color and Shape:Liquid