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TNF

TNF

TNF (Tumor Necrosis Factor) inhibitors are compounds that block the activity of TNF, a cytokine involved in inflammation and the regulation of apoptosis. TNF can induce apoptosis in some cell types while promoting survival and inflammation in others. Inhibiting TNF is crucial in the treatment of autoimmune diseases, chronic inflammatory conditions, and certain cancers. TNF inhibitors help to modulate the immune response and reduce tissue damage caused by excessive inflammation. At CymitQuimica, we provide a diverse range of high-quality TNF inhibitors to support your research in immunology, inflammation, and apoptosis.

Found 92 products of "TNF"

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  • Dacetuzumab

    CAS:
    <p>Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.</p>
    Purity:95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)
    Color and Shape:Liquid
  • Teneliximab

    CAS:
    <p>Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.</p>
    Purity:95.00% - 99.19% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:146.06 kDa
  • Enavatuzumab

    CAS:
    <p>Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.</p>
    Purity:>95%
    Color and Shape:Liquid
  • UCB-9260

    CAS:
    <p>UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.</p>
    Formula:C26H25N5O
    Purity:98.39% - 99.24%
    Color and Shape:Solid
    Molecular weight:423.51
  • Lucatumumab

    CAS:
    <p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>
    Purity:95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)
    Color and Shape:Liquid
  • Certolizumab pegol

    CAS:
    <p>Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.</p>
    Purity:95% - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)
    Color and Shape:Liquid
  • Ruplizumab

    CAS:
    <p>PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.</p>
    Purity:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)
    Color and Shape:Liquid
  • Utomilumab

    CAS:
    <p>Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.</p>
    Formula:C17H24N8O3
    Purity:95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:142.77 kDa
  • (S,S)-TAPI-1 FA


    <p>(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.</p>
    Formula:C27H39N5O7
    Purity:97.61% - 99.72%
    Color and Shape:Solid
    Molecular weight:545.63
  • Ozoralizumab

    CAS:
    <p>Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.</p>
    Purity:SDS-PAGE:> 95%;SEC-HPLC:95.6%
    Color and Shape:Liquid
    Molecular weight:38.44 kDa
  • Conatumumab

    CAS:
    <p>Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).</p>
    Purity:> 95% - > 95%
    Color and Shape:Liquid
    Molecular weight:145 kDa (average)
  • Iscalimab

    CAS:
    <p>Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.</p>
    Purity:>95%
    Color and Shape:Liquid
  • Varlilumab

    CAS:
    <p>Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.</p>
    Purity:SDS-PAGE:95% SEC-HPLC:98.65%
    Color and Shape:Liquid
    Molecular weight:146 kDa
  • Zigakibart

    CAS:
    <p>Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)</p>
    Purity:95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)
    Color and Shape:Liquid
  • Ragifilimab

    CAS:
    <p>Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.</p>
    Purity:SDS-PAGE:95% SEC-HPLC:99.99%
    Color and Shape:Liquid
    Molecular weight:146.46 kDa
  • Cot inhibitor-1 hydrochloride


    <p>Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.</p>
    Formula:C27H28Cl3FN8
    Purity:98.26%
    Color and Shape:Soild
    Molecular weight:589.92
  • TNF-α-IN-9

    CAS:
    <p>TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.</p>
    Formula:C17H14O4
    Purity:98.28%
    Color and Shape:Soild
    Molecular weight:282.29
  • Anti-Mouse TNF α Antibody (TN3-19.12)


    <p>Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.</p>
    Purity:95% - >10mg/ml
    Color and Shape:Odour Liquid
  • RO7567132


    <p>RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.</p>
    Color and Shape:Odour Liquid
  • Pamlectabart


    <p>Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.</p>
    Purity:95%
    Color and Shape:Odour Liquid
  • Relfovetmab

    CAS:
    <p>Relfovetmab is an anti- NGF monoclonal antibody (mAb) [1] .</p>
    Color and Shape:Liquid
  • Onfekafusp alfa

    CAS:
    <p>Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.</p>
    Color and Shape:Liquid
  • Tengonermin

    CAS:
    <p>Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.</p>
    Color and Shape:Liquid
  • Pegsunercept

    CAS:
    <p>Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].</p>
    Color and Shape:Liquid
  • Nerelimomab

    CAS:
    <p>Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].</p>
    Color and Shape:Liquid
  • Asunercept

    CAS:
    <p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>
    Color and Shape:Liquid
  • Tanfanercept

    CAS:
    <p>Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.</p>
    Color and Shape:Liquid
  • Placulumab

    CAS:
    <p>Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.</p>
    Color and Shape:Liquid
  • Ranevetmab

    CAS:
    <p>Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.</p>
    Color and Shape:Liquid
  • Lenercept

    CAS:
    <p>Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].</p>
    Color and Shape:Liquid
  • Atibuclimab

    CAS:
    <p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>
    Purity:> 95% - > 95%
    Color and Shape:Liquid
    Molecular weight:145.28 kDa
  • BIIB023


    <p>BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.</p>
    Color and Shape:Odour Liquid
  • TNF-α Antagonist

    CAS:
    <p>TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with</p>
    Formula:C58H71N11O15S2
    Color and Shape:Solid
    Molecular weight:1226.39
  • Giloralimab

    CAS:
    <p>Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.</p>
    Purity:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)
    Color and Shape:Liquid
  • Sotigalimab

    CAS:
    <p>Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.</p>
    Purity:98.50% - 98.50%
    Color and Shape:Liquid
  • Dapirolizumab


    <p>Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.</p>
    Purity:>95%
    Color and Shape:Liquid
    Molecular weight:145.5 kDa
  • HS-243

    CAS:
    <p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>
    Formula:C17H16N4O3
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:324.33
  • EJMC-1

    CAS:
    <p>EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.</p>
    Formula:C17H11ClN2O4S
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:374.8
  • Tilogotamab

    CAS:
    <p>Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).</p>
    Purity:95%
    Color and Shape:Liquid
  • TNF α Protein, Rabbit, Recombinant


    <p>Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.</p>
    Purity:98% - > 99.9%
    Color and Shape:Lyophilized Powder
    Molecular weight:18 KDa (reducing condition)
  • TNF α Protein, Ferret, Recombinant (His)


    <p>TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:18.88 kDa (predicted) same as Tris-Bis PAGE result.
  • TNF α Protein, Cynomolgus, Recombinant (His)


    <p>TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.
  • TNF α Protein, Human, Recombinant (His & Avi)


    <p>TNF alpha Protein, Human, Recombinant (His &amp; Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.
  • TNF α Protein, Human, Recombinant (aa 57-233, His)


    <p>TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:18 KDa (reducing condition)
  • TNF α Protein, Human, Recombinant (His & Avi), Biotinylated


    <p>TNF alpha Protein, Human, Recombinant (His &amp; Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>
    Color and Shape:Lyophilized Powder
    Molecular weight:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.
  • TNF α Protein, Human, Recombinant (aa 77-233, His)


    <p>TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.</p>
    Purity:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%
    Color and Shape:Lyophilized Powder
    Molecular weight:16 KDa (reducing condition)
  • QNZ

    CAS:
    <p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>
    Formula:C22H20N4O
    Purity:99.17% - 99.18%
    Color and Shape:White Solid
    Molecular weight:356.42
  • R-7050

    CAS:
    <p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>
    Formula:C16H8ClF3N4S
    Purity:98.64% - 99.8%
    Color and Shape:Solid
    Molecular weight:380.77
  • Hispidol

    CAS:
    <p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>
    Formula:C15H10O4
    Purity:97.86% - 98.45%
    Color and Shape:Solid
    Molecular weight:254.24
  • Resatorvid

    CAS:
    <p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>
    Formula:C15H17ClFNO4S
    Purity:99.31% - >99.99%
    Color and Shape:Solid
    Molecular weight:361.82
  • Nodinitib-1

    CAS:
    <p>Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.</p>
    Formula:C14H13N3O2S
    Purity:99.97% - >99.99%
    Color and Shape:Solid
    Molecular weight:287.34
  • C25-140

    CAS:
    <p>C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.</p>
    Formula:C26H31N7O
    Purity:98.81%
    Color and Shape:Solid
    Molecular weight:457.57
  • (Rac)-Benpyrine

    CAS:
    <p>(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.</p>
    Formula:C16H16N6O
    Purity:98.44%
    Color and Shape:Solid
    Molecular weight:308.34
  • Roquinimex

    CAS:
    <p>Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and</p>
    Formula:C18H16N2O3
    Purity:97.69%
    Color and Shape:Solid
    Molecular weight:308.33
  • LASSBio-1135

    CAS:
    <p>LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.</p>
    Formula:C18H14N4
    Purity:99.09%
    Color and Shape:Solid
    Molecular weight:286.33
  • UTL-5g

    CAS:
    <p>UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.</p>
    Formula:C11H8Cl2N2O2
    Purity:99.83%
    Color and Shape:Solid
    Molecular weight:271.1
  • STING-IN-2

    CAS:
    <p>STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.</p>
    Formula:C15H16N2O4
    Purity:98.61%
    Color and Shape:Solid
    Molecular weight:288.3
  • Tulisokibart

    CAS:
    <p>Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.</p>
    Purity:98.38% (SEC-HPLC) - > 95%
    Color and Shape:Liquid
  • Licaminlimab


    <p>Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.</p>
    Color and Shape:Odour Liquid
  • Toralizumab

    CAS:
    <p>Toralizumab: humanized mAb targeting CD40L to curb T cell signaling and explore SLE treatment.</p>
    Color and Shape:Liquid
    Molecular weight:148.43 (kD)
  • Azintuxizumab

    CAS:
    <p>Azintuxizumab, an IgG4 bispecific antibody, targets BCMA, offering dual-action immunotherapy for relapsed/refractory multiple myeloma in preclinical studies.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Inezetamab

    CAS:
    <p>Inezetamab is a bispecific anti- CD40 and anti- MSLN IgG1 monoclonal antibody [1] .</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Bleselumab

    CAS:
    <p>Bleselumab (ASKP 1240) is a humanised monoclonal antibody targeting CD40, inhibiting immune responses, organ transplant rejection.</p>
    Purity:95%
    Color and Shape:Liquid
  • Tabalumab

    CAS:
    <p>Tabalumab (LY2127399) is a humanised monoclonal antibody targeting BAFF that neutralises both soluble and membrane-bound forms of BLyS , autoimmune diseases.</p>
    Purity:95%
    Color and Shape:Liquid
  • Ivuxolimab

    CAS:
    <p>Ivuxolimab is a human IgG2 antibody that acts as an OX40 agonist, promoting T cell responses for anti-tumor immunity research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Cifurtilimab

    CAS:
    <p>Cifurtilimab (SEA-CD40) is a humanised monoclonal antibody acting as a CD40 agonist. It enhances binding to activated FcγRIIIa, anticancer.</p>
    Purity:95%
    Color and Shape:Liquid
  • Afimkibart

    CAS:
    <p>Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.</p>
    Purity:95% - 95%
    Color and Shape:Soild
  • Ravagalimab

    CAS:
    <p>Ravagalimab (ABBV-323) is a CD40 antagonist monoclonal antibody, investigated for Crohn’s disease and Sjögren’s syndrome to evaluate immune modulation.</p>
    Purity:95% - 95%
    Color and Shape:Liquid
  • Frexalimab

    CAS:
    <p>Frexalimab (SAR441344; INX-021), a monoclonal antibody that targets the CD40 ligand (CD40L), shows promise for research in multiple sclerosis [1].</p>
    Color and Shape:Liquid
  • Afelimomab

    CAS:
    <p>Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].</p>
    Color and Shape:Liquid
  • Tecaginlimab

    CAS:
    <p>Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.</p>
    Color and Shape:Liquid
  • Anti-Mouse TNFR2 Antibody (TR75-54.7)


    <p>Anti-Mouse TNFR2 Antibody is an Armenian Hamster-derived IgG inhibitor specifically targeting mouse TNFR2.</p>
    Color and Shape:Odour Liquid
  • Iratumumab

    CAS:
    <p>Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.</p>
    Color and Shape:Liquid
  • IA-14069

    CAS:
    <p>IA-14069 is a TNF-a inhibitor with anti-inflammatory activity and pro-inflammatory cytokine production, and is used in the study of colon cancer.</p>
    Formula:C20H15ClF2O4
    Color and Shape:Soild
    Molecular weight:392.78
  • Cot inhibitor-2

    CAS:
    <p>Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. Orally active.</p>
    Formula:C26H25Cl2FN8
    Purity:98.87%
    Color and Shape:Solid
    Molecular weight:539.43
  • Selicrelumab

    CAS:
    <p>Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.</p>
    Purity:98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)
    Color and Shape:Liquid
  • VU0285655-1

    CAS:
    <p>VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.</p>
    Formula:C25H27N5O2
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:429.51
  • TNF-α-IN-1

    CAS:
    <p>TNF-α-IN-1 is a TNF-α inhibitor.</p>
    Formula:C16H14ClN3O5
    Purity:98.82%
    Color and Shape:Solid
    Molecular weight:363.75
  • UCB-5307

    CAS:
    <p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>
    Formula:C22H21N3O
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:343.42
  • Cot inhibitor-1

    CAS:
    <p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>
    Formula:C27H27Cl2FN8
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:553.46
  • Mitazalimab

    CAS:
    <p>Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.</p>
    Purity:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)
    Color and Shape:Liquid
  • SPD304 dihydrochloride

    CAS:
    <p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>
    Formula:C32H34Cl2F3N3O2
    Purity:99.25%
    Color and Shape:Solid
    Molecular weight:620.53
  • GSK2593074A

    CAS:
    <p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>
    Formula:C27H23N5OS
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:465.57
  • BMS-561392

    CAS:
    <p>BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.</p>
    Formula:C27H32N4O4
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:476.57
  • PK68

    CAS:
    <p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>
    Formula:C22H24N4O3S
    Purity:98.09% - 99.64%
    Color and Shape:Solid
    Molecular weight:424.52
  • Trovafloxacin mesylate

    CAS:
    <p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>
    Formula:C21H19F3N4O6S
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:512.46
  • C 87

    CAS:
    <p>C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks signaling.</p>
    Formula:C24H15ClN6O3S
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:502.93
  • Boserolimab

    CAS:
    <p>Boserolimab (MK-5890) is a chimeric, humanized IgG1κ antibody that targets the signaling regulatory protein CD27 in mice.</p>
    Color and Shape:Liquid
  • CDC801

    CAS:
    <p>CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.</p>
    Formula:C23H24N2O5
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:408.45
  • TNF-α-IN-2

    CAS:
    <p>TNF-α-IN-2 is orally active TNFα inhibitor that distorts the TNFα trimer, causing abnormal signal transduction when it binds to TNFR1, rheumatoid arthritis.</p>
    Formula:C25H21ClF2N6O
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:494.92
  • TNF-α-IN-14

    CAS:
    <p>TNF-α-IN-14, a potent TNFα inhibitor, exhibits a selective inhibition profile with an IC50 of 1.1 µM and demonstrates antiinflammatory properties (WO2001072735A2; compound 12) [1].</p>
    Formula:C22H26O6
    Color and Shape:Solid
    Molecular weight:386.44
  • TNF-α-IN-12

    CAS:
    <p>TNF-α-IN-12, a TNF-α inhibitor with an IC50 of 0.1 μM, can reduce TNF-α blood levels [1].</p>
    Formula:C21H22O6
    Color and Shape:Solid
    Molecular weight:370.4