BCL
BCL inhibitors are compounds that target the BCL-2 family of proteins, which play a key role in the regulation of apoptosis. The BCL-2 family includes both pro-apoptotic and anti-apoptotic members that control the mitochondrial pathway of apoptosis. Inhibiting anti-apoptotic BCL-2 proteins can promote cell death in cancer cells, making BCL inhibitors crucial in cancer therapy research. At CymitQuimica, we provide a comprehensive selection of high-quality BCL inhibitors to support your research in cancer, apoptosis, and cell biology.
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WEHI-539 hydrochloride
CAS:2070018-33-4
WEHI-539 hydrochloride is a selective Bcl-XL inhibitor with an IC50 of 1.1 nM.
Formula:
C31H30ClN5O3S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
620.18
Ref: TM-T13337
| 1mg | 52.00 € |
Estimated delivery in United States, on Monday 2 Dec 2024
IMB-XH1
CAS:292057-76-2
IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.
Formula:
C19H15N3OS
Purity:
98%
Color and Shape:
Solid
Molecular weight:
333.41
Ref: TM-T16028
| 1mg | 55.00 € | ||
| 5mg | 117.00 € | ||
| 10mg | 187.00 € | ||
| 25mg | 314.00 € | ||
| 50mg | 452.00 € | ||
| 100mg | 617.00 € | ||
| 200mg | 831.00 € | ||
| 1mL*10mM (DMSO) | 117.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Dehydrocorydaline chloride
CAS:10605-03-5
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the …
Formula:
C22H24ClNO4
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
401.88
Ref: TM-T10990
| 1mg | 57.00 € | ||
| 5mg | 109.00 € | ||
| 10mg | 157.00 € | ||
| 25mg | 258.00 € | ||
| 50mg | 387.00 € | ||
| 100mg | 550.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
BI-3812
CAS:2166387-64-8
BI-3812 is an inhibitor of BCL6. Which inhibiting the BTB domain of BCL6 (IC50: 3 …
Formula:
C26H32ClN7O5
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
558.03
Ref: TM-T14561
| 1mg | 108.00 € | ||
| 2mg | 159.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 417.00 € | ||
| 25mg | 686.00 € | ||
| 50mg | 917.00 € | ||
| 100mg | 1,291.00 € | ||
| 1mL*10mM (DMSO) | 305.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
BT2
CAS:34576-94-8
BT2 inhibits BDK (IC50: 3.19 μM) & Mcl-1 (Ki: 59 μM), causing helix shift & …
Formula:
C9H4Cl2O2S
Purity:
99.77% - 99.86%
Color and Shape:
Solid
Molecular weight:
247.1
Ref: TM-T14834
| 10mg | 46.00 € | ||
| 25mg | 63.00 € | ||
| 50mg | 78.00 € | ||
| 100mg | 101.00 € | ||
| 500mg | 239.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
S55746
CAS:1448584-12-0
S55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd …
Formula:
C43H42N4O6
Purity:
97.14%
Color and Shape:
Solid
Molecular weight:
710.82
Ref: TM-T12824L
| 1mg | 55.00 € | ||
| 2mg | 80.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 186.00 € | ||
| 25mg | 337.00 € | ||
| 50mg | 539.00 € | ||
| 100mg | 774.00 € | ||
| 1mL*10mM (DMSO) | 130.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
BH3I-1
CAS:300817-68-9
BH3I-1 (BHI1) is a Bcl-2 antagonist.
Formula:
C15H14BrNO3S2
Purity:
97.6% - 98.2%
Color and Shape:
Solid
Molecular weight:
400.31
Ref: TM-T1493
| 1mg | 35.00 € | ||
| 2mg | 46.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 185.00 € | ||
| 50mg | 316.00 € | ||
| 100mg | 528.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
AZD4320
CAS:1357576-48-7
AZD4320 inhibits BCL2/BCLxL; IC50: KPUM-MS3=26nM, KPUM-UH1=17nM, STR-428=170nM.
Formula:
C45H48ClF3N4O7S3
Purity:
99.71%
Color and Shape:
Solid
Molecular weight:
945.53
Ref: TM-T14376
| 1mg | 70.00 € | ||
| 2mg | 90.00 € | ||
| 5mg | 138.00 € | ||
| 10mg | 182.00 € | ||
| 25mg | 362.00 € | ||
| 50mg | 548.00 € | ||
| 100mg | 801.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
MIM1
CAS:509102-00-5
MIM1 (Inhibitor of Mcl-1) is an myeloid cell factor 1 (Mcl-1) inhibitor.
Formula:
C17H21N3O3S
Purity:
99.84%
Color and Shape:
Solid
Molecular weight:
347.43
Ref: TM-T12041
| 1mg | 36.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 78.00 € | ||
| 10mg | 118.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Maritoclax
CAS:1227962-62-0
Maritoclax (Marinopyrrole A) (Marinopyrrole A) is a novel and specific Mcl-1 inhibitor, shows >8 fold …
Formula:
C22H12Cl4N2O4
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
510.15
Ref: TM-T11944
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 143.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 513.00 € | ||
| 100mg | 716.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Rasagiline
CAS:136236-51-6
Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with …
Formula:
C12H13N
Purity:
98% - 99.14%
Color and Shape:
Solid
Molecular weight:
171.24
Ref: TM-T1119
| 10mg | 40.00 € | ||
| 25mg | 60.00 € | ||
| 50mg | 86.00 € | ||
| 100mg | 101.00 € | ||
| 200mg | 137.00 € | ||
| 500mg | 220.00 € | ||
| 1mL*10mM (DMSO) | 47.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
BM 957
CAS:1391107-54-2
BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and <1 nM; IC50s: …
Formula:
C52H56ClF3N6O7S3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1065.68
Ref: TM-T10577
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Bcl-xL antagonist 2
CAS:1235032-75-3
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of …
Formula:
C21H16N4O3S2
Purity:
99.26%
Color and Shape:
Solid
Molecular weight:
436.51
Ref: TM-T38622
| 1mg | 79.00 € | ||
| 5mg | 171.00 € | ||
| 10mg | 254.00 € | ||
| 25mg | 459.00 € | ||
| 50mg | 638.00 € | ||
| 100mg | 821.00 € | ||
| 200mg | 1,099.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Lisaftoclax
CAS:2180923-05-9
Lisaftoclax, an oral Bcl-2/Bcl-xl inhibitor (IC50: 2 nM & 5.9 nM), treats CLL by promoting …
Formula:
C45H48ClN7O8S
Purity:
97.14% - 98.22%
Color and Shape:
Solid
Molecular weight:
882.42
Ref: TM-T10483
| 1mg | 174.00 € | ||
| 5mg | 386.00 € | ||
| 10mg | 554.00 € | ||
| 25mg | 821.00 € | ||
| 50mg | 1,098.00 € | ||
| 100mg | 1,489.00 € | ||
| 1mL*10mM (DMSO) | 555.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Thevetiaflavone
CAS:29376-68-9
Thevetiaflavone, a natural flavonoid from W. indica, blocks LDH leakage, boosting cell survival.
Formula:
C16H12O5
Purity:
98%
Color and Shape:
Solid
Molecular weight:
284.26
Ref: TM-T13922
| 5mg | 823.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Isolimonexic acid
CAS:73904-93-5
Isolimonexic acid exhibits cytotoxicity on MCF-7 cell lines, it also inhibits Panc-28 cancer cell growth.
Formula:
C26H30O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
502.51
Ref: TM-TN4307
| 5mg | 519.00 € | ||
| 1mL*10mM (DMSO) | 803.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Ferruginol
CAS:514-62-5
Ferruginol exhibits anti-cancer, anti-inflammatory, cardioprotective properties and can trigger NSCLC cell apoptosis.
Formula:
C20H30O
Purity:
98%
Color and Shape:
Solid
Molecular weight:
286.459
Ref: TM-TN1642
| 5mg | 435.00 € | ||
| 1mL*10mM (DMSO) | 444.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PROTAC Bcl2 degrader-1
CAS:2378801-85-3
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 …
Formula:
C45H45BrN6O10S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
941.84
Ref: TM-T10485
| 1mg | 429.00 € | ||
| 5mg | 764.00 € | ||
| 10mg | 1,165.00 € | ||
| 50mg | To inquire | ||
| 100mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Isoverticine
CAS:23496-43-7
Isoverticine exhibits significant antitussive, expectorant and anti-inflammatory activities, it also displays significant cytotoxicity.
Formula:
C27H45NO3
Purity:
99.88%
Color and Shape:
Solid
Molecular weight:
431.65
Ref: TM-TN1807
| 1mg | 68.00 € | ||
| 2mg | 94.00 € | ||
| 5mg | 128.00 € | ||
| 10mg | 208.00 € | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Scutebarbatine A
CAS:176520-13-1
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via …
Formula:
C32H34N2O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
558.62
Ref: TM-TN2191
| 25mg | 1,435.00 € | ||
| 1mL*10mM (DMSO) | 1,225.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
