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BCL

BCL

BCL inhibitors are compounds that target the BCL-2 family of proteins, which play a key role in the regulation of apoptosis. The BCL-2 family includes both pro-apoptotic and anti-apoptotic members that control the mitochondrial pathway of apoptosis. Inhibiting anti-apoptotic BCL-2 proteins can promote cell death in cancer cells, making BCL inhibitors crucial in cancer therapy research. At CymitQuimica, we provide a comprehensive selection of high-quality BCL inhibitors to support your research in cancer, apoptosis, and cell biology.

Found 11 products of "BCL"

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  • BM 957
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    BM 957

    CAS:
    <p>BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and &lt;1 nM; IC50s: 5.4 and 6.0 nM).</p>
    Formula:C52H56ClF3N6O7S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1065.68

    Ref: TM-T10577

  • Mcl-1 inhibitor 3
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    Mcl-1 inhibitor 3

    CAS:
    <p>Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate</p>
    Formula:C40H52ClF2N5O7S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:820.39

    Ref: TM-T11972

  • PROTAC Bcl2 degrader-1
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    PROTAC Bcl2 degrader-1

    CAS:
    <p>PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).</p>
    Formula:C45H45BrN6O10S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:941.84

    Ref: TM-T10485

  • Mcl1-IN-12
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    Mcl1-IN-12

    CAS:
    <p>Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.</p>
    Formula:C45H46N4O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:803

    Ref: TM-T11974

  • Pyridoclax
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    Pyridoclax

    CAS:
    <p>Pyridoclax is an inhibitor of potential Mcl-1.</p>
    Formula:C29H22N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.51

    Ref: TM-T16694

  • S55746 hydrochloride
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    S55746 hydrochloride

    CAS:
    <p>S55746 hydrochloride is a potent, orally active and selective inhibitor of BCL-2(Ki of 1.3 nM and a Kd of 3.9 nM),with antitumor activity with low toxicity.</p>
    Formula:C43H43ClN4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:747.28

    Ref: TM-T12824

  • Tapotoclax
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    Tapotoclax

    CAS:
    <p>Tapotoclax (AMG-176) is an orally active MCL1 inhibitor for the study of myeloid leukemia.</p>
    Formula:C33H41ClN2O5S
    Purity:98.8%
    Color and Shape:Solid
    Molecular weight:613.21

    Ref: TM-T14213

  • MCL-1/BCL-2-IN-1
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    MCL-1/BCL-2-IN-1

    CAS:
    <p>MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective dual inhibitor of Mcl-1 and Bcl-2 with IC 50 s of 4.45 and 3.18 μM, respectively [1].</p>
    Formula:C31H27BrN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:587.53

    Ref: TM-T11968

  • Mcl1-IN-11
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    Mcl1-IN-11

    CAS:
    <p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>
    Formula:C38H41N3O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:683.88

    Ref: TM-T11973

  • Mcl1-IN-9
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    Mcl1-IN-9

    CAS:
    <p>Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.</p>
    Formula:C37H39ClN4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:639.18

    Ref: TM-T11977

  • WEHI-539 hydrochloride
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    WEHI-539 hydrochloride

    CAS:
    <p>WEHI-539 hydrochloride is a selective Bcl-XL inhibitor with an IC50 of 1.1 nM.</p>
    Formula:C31H30ClN5O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:620.18

    Ref: TM-T13337

    1mg
    Discontinued
    Discontinued product