BCL
BCL inhibitors are compounds that target the BCL-2 family of proteins, which play a key role in the regulation of apoptosis. The BCL-2 family includes both pro-apoptotic and anti-apoptotic members that control the mitochondrial pathway of apoptosis. Inhibiting anti-apoptotic BCL-2 proteins can promote cell death in cancer cells, making BCL inhibitors crucial in cancer therapy research. At CymitQuimica, we provide a comprehensive selection of high-quality BCL inhibitors to support your research in cancer, apoptosis, and cell biology.
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MCL-1/BCL-2-IN-2
CAS:2163793-44-8
MCL-1/BCL-2-IN-2 is a selective Mcl-1 and Bcl-2 inhibitor with potential antitumor activity for tumor research.
Formula:
C20H15BrN2O2S
Purity:
98.03%
Color and Shape:
Solid
Molecular weight:
427.31
Ref: TM-T11969
| 2mg | 35.00 € | ||
| 5mg | 52.00 € | ||
| 10mg | 83.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 346.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Sabutoclax
CAS:1228108-65-3
Sabutoclax (BI-97C1)(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of …
Formula:
C42H40N2O8
Purity:
98.5%
Color and Shape:
Solid
Molecular weight:
700.78
Ref: TM-T6650
| 1mg | 69.00 € | ||
| 5mg | 150.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 462.00 € | ||
| 50mg | 732.00 € | ||
| 100mg | 994.00 € | ||
| 1mL*10mM (DMSO) | 165.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
MIK665
CAS:1799631-75-6
MIK665 (S-64315) (S-64315) has an inhibitory effect on myeloid leukemia.
Formula:
C47H44ClFN6O6S
Purity:
99.28%
Color and Shape:
Solid
Molecular weight:
875.41
Ref: TM-T12629L
| 1mg | 131.00 € | ||
| 5mg | 270.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 702.00 € | ||
| 50mg | 985.00 € | ||
| 100mg | 1,327.00 € | ||
| 500mg | 2,672.00 € | ||
| 1mL*10mM (DMSO) | 414.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CLZ-8
CAS:678158-55-9
CLZ-8 (Mcl1-IN-8) is a Mcl-1-PUMA inhibitor with radioprotective activity and inhibits radiation-induced overexpression of PUMA.
Formula:
C22H23N3O2S
Purity:
99.85%
Color and Shape:
Solid
Molecular weight:
393.5
Ref: TM-T16030
| 1mg | 50.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Dehydrocavidine
CAS:83218-34-2
Dehydrocavidine inhibits tumor growth by inducing apoptosis in MCF-7 cells, regulating Bax/Bcl-2, and activating caspases.
Formula:
C21H18NO4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
348.37
Ref: TM-TN1139
| 1mg | 193.00 € | ||
| 5mg | 433.00 € | ||
| 10mg | 649.00 € | ||
| 25mg | 1,166.00 € | ||
| 50mg | 1,756.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Pyridoclax
CAS:1651890-44-6
Pyridoclax is an inhibitor of potential Mcl-1.
Formula:
C29H22N4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
426.51
Ref: TM-T16694
| 2mg | 88.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
AZD-5991
CAS:2143061-81-6
AZD-5991 is a potent and selective Mcl-1 inhibitor (IC50: 0.7 nM in FRET assay; Kd: …
Formula:
C35H34ClN5O3S2
Color and Shape:
Solid
Molecular weight:
672.26
Ref: TM-T10434
| 2mg | 331.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Coronarin D
CAS:119188-37-3
Coronarin D has antifungal properties, with 2 mg/mL MIC & 4 mg/mL MFC against C. …
Formula:
C20H30O3
Purity:
98%
Color and Shape:
Solid
Molecular weight:
318.457
Ref: TM-TN3708
| 5mg | 1,654.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
UMI-77
CAS:518303-20-3
UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1.Cost-effective and …
Formula:
C18H14BrNO5S2
Purity:
96% - 99.57%
Color and Shape:
Solid
Molecular weight:
468.34
Ref: TM-T6034
| 1mg | 42.00 € | ||
| 2mg | 60.00 € | ||
| 5mg | 91.00 € | ||
| 10mg | 123.00 € | ||
| 25mg | 213.00 € | ||
| 50mg | 349.00 € | ||
| 100mg | 499.00 € | ||
| 200mg | 713.00 € | ||
| 500mg | 1,075.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TW-37
CAS:877877-35-5
TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).
Formula:
C33H35NO6S
Purity:
97.06% - ≥95%
Color and Shape:
Solid
Molecular weight:
573.7
Ref: TM-T6281
| 1mg | 40.00 € | ||
| 2mg | 52.00 € | ||
| 5mg | 68.00 € | ||
| 10mg | 111.00 € | ||
| 25mg | 209.00 € | ||
| 50mg | 348.00 € | ||
| 100mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
BDA-366
CAS:1909226-00-1
BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = …
Formula:
C24H29N3O4
Purity:
99.46%
Color and Shape:
Soild
Molecular weight:
423.5
Ref: TM-T6778
| 1mg | 51.00 € | ||
| 5mg | 106.00 € | ||
| 10mg | 173.00 € | ||
| 25mg | 290.00 € | ||
| 50mg | 421.00 € | ||
| 100mg | 588.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Gossypol (acetic acid)
CAS:12542-36-8
Gossypol acetic acid (AT101), a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, …
Formula:
C32H34O10
Purity:
96.76% - 98.57%
Color and Shape:
Yellow Crystal Powder
Molecular weight:
578.61
Ref: TM-T2730
| 25mg | 35.00 € | ||
| 50mg | 46.00 € | ||
| 100mg | 69.00 € | ||
| 500mg | 148.00 € | ||
| 1mL*10mM (DMSO) | 51.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Erianin
CAS:95041-90-0
Erianin, from Dendrobium chrysotoxum, inhibits tumor growth, causes necrosis, disrupts endothelial cells, and induces apoptosis …
Formula:
C18H22O5
Purity:
97.78% - 99.38%
Color and Shape:
Solid
Molecular weight:
318.36
Ref: TM-T3864
| 5mg | 48.00 € | ||
| 10mg | 71.00 € | ||
| 25mg | 94.00 € | ||
| 50mg | 128.00 € | ||
| 100mg | 183.00 € | ||
| 1mL*10mM (DMSO) | 49.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
A-1331852
CAS:1430844-80-6
A-1331852 is a potent and selectiveBCL-XL inhibitor and may be useful in the treatment of …
Formula:
C38H38N6O3S
Purity:
100% - 98.54%
Color and Shape:
Solid
Molecular weight:
658.81
Ref: TM-T6749
| 1mg | 51.00 € | ||
| 2mg | 71.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 174.00 € | ||
| 25mg | 360.00 € | ||
| 50mg | 538.00 € | ||
| 100mg | 769.00 € | ||
| 1mL*10mM (DMSO) | 165.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
TCPOBOP
CAS:76150-91-9
TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.
Formula:
C16H8Cl4N2O2
Purity:
99.70%
Color and Shape:
Solid
Molecular weight:
402.06
Ref: TM-T17018
| 5mg | 49.00 € | ||
| 10mg | 73.00 € | ||
| 25mg | 121.00 € | ||
| 50mg | 193.00 € | ||
| 100mg | 305.00 € | ||
| 200mg | 457.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Gartanin
CAS:33390-42-0
Gartanin enhances androgen receptor degradation and has neuroprotective effects by boosting HO-1, AMPK, SIRT1, and …
Formula:
C23H24O6
Purity:
99.64% - 99.85%
Color and Shape:
Solid
Molecular weight:
396.43
Ref: TM-TN1677
| 1mg | 156.00 € | ||
| 5mg | 366.00 € | ||
| 10mg | 555.00 € | ||
| 25mg | 881.00 € | ||
| 50mg | 1,197.00 € | ||
| 1mL*10mM (DMSO) | 374.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Se-Methylselenocysteine
CAS:26046-90-2
Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown …
Formula:
C4H9NO2Se
Purity:
99.49% - ≥98%
Color and Shape:
White To Slightly Yellow Powder
Molecular weight:
182.08
Ref: TM-T7727
| 5mg | 51.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 139.00 € | ||
| 50mg | 212.00 € | ||
| 100mg | 314.00 € | ||
| 200mg | 468.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Orobol
CAS:480-23-9
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.
Formula:
C15H10O6
Purity:
98% - 98%
Color and Shape:
Solid
Molecular weight:
286.24
Ref: TM-TN2019
| 1mg | 178.00 € | ||
| 2mg | 268.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Ciwujianoside B
CAS:114902-16-8
Ciwujianoside B (acanthopanax senticosides B) is the main component of Acanthopanax, can relieve fatigue, enhance …
Formula:
C58H92O25
Purity:
99.73% - 99.86%
Color and Shape:
Solid
Molecular weight:
1189.34
Ref: TM-T3344
| 1mg | 82.00 € | ||
| 5mg | 147.00 € | ||
| 10mg | 230.00 € | ||
| 25mg | 388.00 € | ||
| 50mg | 552.00 € | ||
| 1mL*10mM (DMSO) | 274.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
Alpinetin
CAS:36052-37-6
Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & …
Formula:
C16H14O4
Purity:
99.61%
Color and Shape:
Solid
Molecular weight:
270.28
Ref: TM-T3867
| 5mg | 50.00 € | ||
| 10mg | 75.00 € | ||
| 25mg | 137.00 € | ||
| 50mg | 194.00 € | ||
| 100mg | 291.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Wednesday 11 Dec 2024
