IAP
IAP (Inhibitor of Apoptosis Protein) inhibitors are compounds that block the activity of IAPs, a family of proteins that prevent apoptosis by inhibiting caspases and other components of the apoptotic machinery. IAP inhibitors promote apoptosis in cancer cells by neutralizing these survival signals, making them important tools in cancer research and therapy. At CymitQuimica, we offer a comprehensive range of high-quality IAP inhibitors to support your research in oncology, apoptosis, and therapeutic development.
Found 67 products of "IAP"
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T-3256336
CAS:T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Formula:C31H45F2N5O5Purity:98%Color and Shape:SolidMolecular weight:605.72A 410099.1
CAS:A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.Formula:C27H41ClN4O3Purity:99.30%Color and Shape:SolidMolecular weight:505.1CUDC-427
CAS:CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.Formula:C29H36N6O4SPurity:99.92%Color and Shape:SolidMolecular weight:564.7Anticancer agent 127
CAS:Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,Formula:C26H37FN4O6SPurity:98%Color and Shape:SolidMolecular weight:552.66Anticancer agent 128
CAS:Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19Formula:C26H38N4O4Purity:98%Color and Shape:SolidMolecular weight:470.6XIAP degrader-1
XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).Formula:C34H45N5O4Color and Shape:SolidMolecular weight:587.75XIAP/cIAP1 antagonist-1
Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.
Color and Shape:Solid
