IAP
IAP (Inhibitor of Apoptosis Protein) inhibitors are compounds that block the activity of IAPs, a family of proteins that prevent apoptosis by inhibiting caspases and other components of the apoptotic machinery. IAP inhibitors promote apoptosis in cancer cells by neutralizing these survival signals, making them important tools in cancer research and therapy. At CymitQuimica, we offer a comprehensive range of high-quality IAP inhibitors to support your research in oncology, apoptosis, and therapeutic development.
Found 71 products for "IAP".
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BV6
CAS:BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formula:C70H96N10O8Purity:97.46% - 99.82%Color and Shape:SolidMolecular weight:1205.57Ref: TM-T6428
1mg47.00€2mg62.00€5mg94.00€10mg137.00€1mL*10mM (DMSO)170.00€25mg270.00€50mg442.00€100mg707.00€MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Formula:C27H26N2O4SPurity:97.27% - 99.57%Color and Shape:SolidMolecular weight:474.57Ref: TM-T3653
2mg39.00€5mg58.00€1mL*10mM (DMSO)62.00€10mg92.00€25mg167.00€50mg260.00€100mg409.00€200mg590.00€Xevinapant
CAS:Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formula:C32H43N5O4Purity:98% - 99.94%Color and Shape:SolidMolecular weight:561.71Ref: TM-T6763
1mg40.00€2mg54.00€5mg88.00€10mg124.00€1mL*10mM (DMSO)138.00€25mg260.00€50mg416.00€100mg647.00€200mg954.00€AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formula:C60H82N8O10Purity:97.76%Color and Shape:White SolidMolecular weight:1075.36LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formula:C26H33FN4O3SPurity:99.13% - 99.87%Color and Shape:White SolidMolecular weight:500.63Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formula:C15H16O3Purity:98.76%Color and Shape:SolidMolecular weight:244.29Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formula:C17H26O4Purity:97.07% - 99.95%Color and Shape:Orange SolidMolecular weight:294.39CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Color and Shape:Lyophilized PowderMolecular weight:33-55 KDa (reducing condition)Ref: TM-TMPJ-00614
5µg92.00€10µg149.00€20µg231.00€50µg439.00€100µg682.00€200µg1,063.00€500µg1,918.00€1mg2,890.00€CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Color and Shape:Lyophilized PowderMolecular weight:60-90 KDa (reducing condition)Ref: TM-TMPJ-00613
5µg84.00€10µg120.00€20µg178.00€50µg351.00€100µg563.00€200µg888.00€500µg1,710.00€1mg2,457.00€CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Color and Shape:Lyophilized PowderMolecular weight:60-70 KDa (reducing condition)MX107
CAS:MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.Formula:C24H28N2O2Color and Shape:SolidMolecular weight:376.49MDM2/XIAP-IN-3
CAS:MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFormula:C29H30N2O5SColor and Shape:SolidMolecular weight:518.62A 410099.1
CAS:A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.Formula:C27H41ClN4O3Purity:99.30% - 99.53%Color and Shape:White SolidMolecular weight:505.1NOC-5
CAS:NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.Formula:C6H16N4O2Purity:98%Color and Shape:White SolidMolecular weight:176.22T-3256336
CAS:T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Formula:C31H45F2N5O5Purity:98%Color and Shape:SolidMolecular weight:605.72CUDC-427
CAS:CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.Formula:C29H36N6O4SPurity:99.92%Color and Shape:SolidMolecular weight:564.7Anticancer agent 128
CAS:Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19Formula:C26H38N4O4Purity:98%Color and Shape:SolidMolecular weight:470.6Anticancer agent 127
CAS:Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,Formula:C26H37FN4O6SPurity:98%Color and Shape:SolidMolecular weight:552.66XIAP antagonist 1
CAS:XIAP antagonist 1 (compound A4) is a specific XIAP inhibitor that promotes the degradation of XIAP through the ubiquitin-proteasome pathway [1].Formula:C23H25ClN4O3Color and Shape:SolidMolecular weight:440.92XIAP degrader-1
XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).Formula:C34H45N5O4Color and Shape:SolidMolecular weight:587.75XIAP/cIAP1 antagonist-1
Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.Color and Shape:Solid
