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IAP

IAP

IAP (Inhibitor of Apoptosis Protein) inhibitors are compounds that block the activity of IAPs, a family of proteins that prevent apoptosis by inhibiting caspases and other components of the apoptotic machinery. IAP inhibitors promote apoptosis in cancer cells by neutralizing these survival signals, making them important tools in cancer research and therapy. At CymitQuimica, we offer a comprehensive range of high-quality IAP inhibitors to support your research in oncology, apoptosis, and therapeutic development.

Found 66 products of "IAP"

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  • Isolinderalactone
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    Isolinderalactone

    CAS:
    <p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>
    Formula:C15H16O3
    Purity:99.62%
    Color and Shape:Solid
    Molecular weight:244.29

    Ref: TM-T8213

  • Polygalacin D
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    Polygalacin D

    CAS:
    <p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>
    Formula:C57H92O27
    Purity:98.95% - ≥98%
    Color and Shape:Solid
    Molecular weight:1209.4

    Ref: TM-TN2091

  • 4-Methylsalicylic acid
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    4-Methylsalicylic acid

    CAS:
    <p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>
    Formula:C8H8O3
    Purity:99.64%
    Color and Shape:Solid Solid Crystalline
    Molecular weight:152.15

    Ref: TM-T22225

  • SM-164
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    SM-164

    CAS:
    <p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>
    Formula:C62H84N14O6
    Purity:98.53% - 99.92%
    Color and Shape:Solid
    Molecular weight:1121.42

    Ref: TM-T12932L

  • MX69
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    MX69

    CAS:
    <p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>
    Formula:C27H26N2O4S
    Purity:97.27% - 99.57%
    Color and Shape:Solid
    Molecular weight:474.57

    Ref: TM-T3653

  • BV6
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    BV6

    CAS:
    <p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>
    Formula:C70H96N10O8
    Purity:97.46% - 99.82%
    Color and Shape:Solid
    Molecular weight:1205.57

    Ref: TM-T6428

  • AZD5582 acetate (1258392-53-8 free base)
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    AZD5582 acetate (1258392-53-8 free base)

    <p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>
    Formula:C60H82N8O10
    Purity:97.76%
    Color and Shape:Solid
    Molecular weight:1075.36

    Ref: TM-T14378L

  • T-3256336
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    T-3256336

    CAS:
    <p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>
    Formula:C31H45F2N5O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:605.72

    Ref: TM-T26246

  • MX107
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    MX107

    CAS:
    <p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>
    Formula:C24H28N2O2
    Color and Shape:Solid
    Molecular weight:376.49

    Ref: TM-T69845

  • A 410099.1
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    A 410099.1

    CAS:
    <p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>
    Formula:C27H41ClN4O3
    Purity:99.30%
    Color and Shape:Solid
    Molecular weight:505.1

    Ref: TM-T36890

  • MDM2/XIAP-IN-3
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    MDM2/XIAP-IN-3

    CAS:
    <p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>
    Formula:C29H30N2O5S
    Color and Shape:Solid
    Molecular weight:518.62

    Ref: TM-T79483

  • CUDC-427
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    CUDC-427

    CAS:
    <p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>
    Formula:C29H36N6O4S
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:564.7

    Ref: TM-T15018

  • Anticancer agent 128
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    Anticancer agent 128

    CAS:
    <p>Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19</p>
    Formula:C26H38N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:470.6

    Ref: TM-T79248

  • Anticancer agent 127
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    Anticancer agent 127

    CAS:
    <p>Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,</p>
    Formula:C26H37FN4O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:552.66

    Ref: TM-T79247

  • CymitQuimica logo
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    XIAP degrader-1

    <p>XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).</p>
    Formula:C34H45N5O4
    Color and Shape:Solid
    Molecular weight:587.75

    Ref: TM-T64161

  • CymitQuimica logo
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    XIAP/cIAP1 antagonist-1

    <p>Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.</p>
    Color and Shape:Solid

    Ref: TM-T64302