IAP
IAP (Inhibitor of Apoptosis Protein) inhibitors are compounds that block the activity of IAPs, a family of proteins that prevent apoptosis by inhibiting caspases and other components of the apoptotic machinery. IAP inhibitors promote apoptosis in cancer cells by neutralizing these survival signals, making them important tools in cancer research and therapy. At CymitQuimica, we offer a comprehensive range of high-quality IAP inhibitors to support your research in oncology, apoptosis, and therapeutic development.
Found 66 products of "IAP"
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CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
<p>CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.</p>Color and Shape:Lyophilized PowderMolecular weight:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
<p>CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Color and Shape:Lyophilized PowderMolecular weight:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
<p>CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.</p>Purity:97.8%Color and Shape:Lyophilized PowderMolecular weight:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase Protein, Human, Recombinant (His)
<p>Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Purity:98.4%Color and Shape:Lyophilized PowderMolecular weight:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)Embelin
CAS:<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Formula:C17H26O4Purity:97.07% - 99.88%Color and Shape:SolidMolecular weight:294.39GDC-0152
CAS:<p>GDC-0152 is a potent inhibitor of IAPs.</p>Formula:C25H34N6O3SPurity:97.18% - 99.32%Color and Shape:SolidMolecular weight:498.64Birinapant
CAS:<p>Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of</p>Formula:C42H56F2N8O6Purity:97.08% - ≥95%Color and Shape:SolidMolecular weight:806.94ASTX660
CAS:<p>Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.</p>Formula:C30H42FN5O3Purity:98.33% - 99.85%Color and Shape:SolidMolecular weight:539.68Xevinapant
CAS:<p>Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.</p>Formula:C32H43N5O4Purity:98% - 99.94%Color and Shape:SolidMolecular weight:561.71LCL161
CAS:<p>LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.</p>Formula:C26H33FN4O3SPurity:99.13% - 99.87%Color and Shape:SolidMolecular weight:500.63Isolinderalactone
CAS:<p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>Formula:C15H16O3Purity:99.62%Color and Shape:SolidMolecular weight:244.29Polygalacin D
CAS:<p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>Formula:C57H92O27Purity:98.95% - ≥98%Color and Shape:SolidMolecular weight:1209.44-Methylsalicylic acid
CAS:<p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>Formula:C8H8O3Purity:99.64%Color and Shape:Solid Solid CrystallineMolecular weight:152.15SM-164
CAS:<p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>Formula:C62H84N14O6Purity:98.53% - 99.92%Color and Shape:SolidMolecular weight:1121.42MX69
CAS:<p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>Formula:C27H26N2O4SPurity:97.27% - 99.57%Color and Shape:SolidMolecular weight:474.57BV6
CAS:<p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>Formula:C70H96N10O8Purity:97.46% - 99.82%Color and Shape:SolidMolecular weight:1205.57AZD5582 acetate (1258392-53-8 free base)
<p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>Formula:C60H82N8O10Purity:97.76%Color and Shape:SolidMolecular weight:1075.36T-3256336
CAS:<p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>Formula:C31H45F2N5O5Purity:98%Color and Shape:SolidMolecular weight:605.72MX107
CAS:<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Formula:C24H28N2O2Color and Shape:SolidMolecular weight:376.49A 410099.1
CAS:<p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>Formula:C27H41ClN4O3Purity:99.30%Color and Shape:SolidMolecular weight:505.1
