Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
Found 264 products of "Integrin"
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RWJ 50271
CAS:RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formula:C18H17F3N4O2SPurity:99.09%Color and Shape:SolidMolecular weight:410.41Ref: TM-T12783
1mg127.00€5mg311.00€10mg472.00€25mg747.00€50mg1,017.00€100mg1,311.00€200mg1,786.00€1mL*10mM (DMSO)344.00€Otelixizumab
CAS:Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Purity:>95%Color and Shape:LiquidOrbofiban TFA
CAS:Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormula:C19H24F3N5O6Purity:97.21% - 98.72%Color and Shape:SolidMolecular weight:475.42ATN-161 trifluoroacetate salt
CAS:ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formula:C25H36F3N9O10SPurity:98% - 99.98%Color and Shape:SolidMolecular weight:711.67Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:144.22 kDaAbrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Purity:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Color and Shape:LiquidCibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Purity:SDS-PAGE:99.1%;SEC-HPLC:96.5%Color and Shape:LiquidMolecular weight:191.1 kDaForalumab
CAS:Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.Purity:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Color and Shape:LiquidTadocizumab
CAS:Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Purity:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Color and Shape:LiquidMolecular weight:47.59 kDaEfalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Purity:SDS-PAGE:95% SEC-HPLC:98.77%Color and Shape:LiquidMolecular weight:146.14 kDaArg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Formula:C17H31N7O10Purity:98.14%Color and Shape:SolidMolecular weight:493.47Abituzumab
CAS:Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Purity:>95%Color and Shape:LiquidVedolizumab
CAS:Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.Purity:SDS-PAGE:98.4%;SEC-HPLC:99.1%Color and Shape:LiquidMolecular weight:146.80 kDaElarofiban TFA
CAS:Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Formula:C26H34F6N4O8Purity:99.08%Color and Shape:SoildMolecular weight:644.56Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaTeplizumab
CAS:Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Purity:SDS-PAGE:95.8%;SEC-HPLC:99.7%Color and Shape:LiquidMolecular weight:145.79 kDaTidutamab
CAS:Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).Purity:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Color and Shape:LiquidAc-MRGDH-NH2
Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.Formula:C25H41N11O8SColor and Shape:SolidMolecular weight:655.727LDV FITC
CAS:fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formula:C69H81N11O17SPurity:98%Color and Shape:SolidMolecular weight:1368.53Mumefural
CAS:Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.
Formula:C12H12O9Color and Shape:SolidMolecular weight:300.22
