Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
Read more
ATN-161 trifluoroacetate salt
CAS:904763-27-5
ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival …
Formula:
C25H36F3N9O10S
Purity:
98% - 99.98%
Color and Shape:
Solid
Molecular weight:
711.67
Ref: TM-T10397
| 1mg | 45.00 € | ||
| 2mg | 58.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 124.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 369.00 € | ||
| 100mg | 548.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
RWJ 50271
CAS:162112-37-0
RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.
Formula:
C18H17F3N4O2S
Purity:
99.09%
Color and Shape:
Solid
Molecular weight:
410.41
Ref: TM-T12783
| 1mg | 156.00 € | ||
| 5mg | 372.00 € | ||
| 10mg | 557.00 € | ||
| 25mg | 875.00 € | ||
| 50mg | 1,167.00 € | ||
| 100mg | 1,584.00 € | ||
| 1mL*10mM (DMSO) | 421.00 € |
Estimated delivery in United States, on Wednesday 4 Dec 2024
Vedolizumab
CAS:943609-66-3
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of …
Purity:
SDS-PAGE:98.4%;SEC-HPLC:99.1%
Color and Shape:
Liquid
Molecular weight:
146.80 kDa
Ref: TM-T9914
| 1mg | 185.00 € | ||
| 5mg | 503.00 € | ||
| 10mg | 727.00 € | ||
| 25mg | 1,103.00 € | ||
| 50mg | 1,486.00 € | ||
| 100mg | 2,037.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Bimosiamose
CAS:187269-40-5
Bimosiamose has anti-inflammatory effects[1].
Formula:
C46H54O16
Purity:
98%
Color and Shape:
Solid
Molecular weight:
862.91
Ref: TM-T14574
| 1mg | 202.00 € | ||
| 5mg | 738.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Gantofiban
CAS:183547-57-1
Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease …
Formula:
C21H29N5O6
Purity:
99.21%
Color and Shape:
Liquid
Molecular weight:
447.48
Ref: TM-T68078
| 1mg | 178.00 € | ||
| 5mg | 446.00 € | ||
| 10mg | 642.00 € | ||
| 25mg | 1,003.00 € | ||
| 50mg | 1,383.00 € | ||
| 100mg | 1,849.00 € | ||
| 500mg | 3,662.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PLN-1474
CAS:2408065-32-5
PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.
Formula:
C24H37N3O4
Purity:
99.25%
Color and Shape:
Soild
Molecular weight:
431.57
Ref: TM-T60101
| 1mg | 63.00 € | ||
| 5mg | 143.00 € | ||
| 10mg | 222.00 € | ||
| 25mg | 370.00 € | ||
| 50mg | 528.00 € | ||
| 100mg | 715.00 € | ||
| 1mL*10mM (DMSO) | 168.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Abrilumab
CAS:1342290-43-0
Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.
Color and Shape:
Liquid
Ref: TM-T76737
| 1mg | 412.00 € | ||
| 5mg | 1,278.00 € | ||
| 10mg | 2,064.00 € | ||
| 25mg | 3,869.00 € | ||
| 50mg | 5,248.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
2-Methylbutyrylcarnitine chloride
2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating …
Formula:
C12H24ClNO4
Color and Shape:
Liquid
Molecular weight:
281.78
Ref: TM-T200397
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
Tadocizumab
CAS:339086-80-5
Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.
Color and Shape:
Liquid
Ref: TM-T76979
| 1mg | 279.00 € | ||
| 5mg | 675.00 € | ||
| 10mg | 921.00 € | ||
| 25mg | 1,391.00 € | ||
| 50mg | 1,839.00 € | ||
| 100mg | 2,511.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Efalizumab
CAS:214745-43-4
Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.
Purity:
SDS-PAGE:95% SEC-HPLC:98.77%
Color and Shape:
Liquid
Molecular weight:
146.14 kDa
Ref: TM-T76924
| 1mg | 185.00 € | ||
| 5mg | 480.00 € | ||
| 10mg | 765.00 € | ||
| 25mg | 1,140.00 € | ||
| 50mg | 1,523.00 € | ||
| 100mg | 2,074.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Abciximab
CAS:143653-53-6
Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.
Purity:
SDS-PAGE:95.2%;SEC-HPLC:95.9%
Color and Shape:
Liquid
Molecular weight:
95.18 kDa
Ref: TM-T76844
| 1mg | 198.00 € | ||
| 5mg | 523.00 € | ||
| 10mg | 823.00 € | ||
| 25mg | 1,234.00 € | ||
| 50mg | 1,652.00 € | ||
| 100mg | 2,255.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
STX-100
STX-100 is a humanized antibody targeting integrin αvβ6 with antitumor activity and inhibits pSMAD2 for …
Purity:
95% - 95%
Ref: TM-T9901A-062
| 1mg | 256.00 € | ||
| 5mg | 821.00 € | ||
| 10mg | 1,317.00 € | ||
| 25mg | 2,418.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Etrolizumab
CAS:1044758-60-2
Etrolizumab (rhuMAb Beta7) is an anti-β7 integrin monoclonal antibody that selectively blocks the transport and …
Purity:
95% - 95%
Color and Shape:
Liquid
Ref: TM-T77154
| 1mg | 280.00 € | ||
| 5mg | 678.00 € | ||
| 10mg | 924.00 € | ||
| 25mg | 1,396.00 € | ||
| 50mg | 1,846.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
K34c hydrochloride
K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.
Formula:
C38H50ClN5O2
Purity:
100% - 99.95%
Color and Shape:
Soild
Molecular weight:
644.29
Ref: TM-T41151L
| 1mg | 326.00 € | ||
| 5mg | 772.00 € | ||
| 10mg | 1,049.00 € | ||
| 25mg | 1,481.00 € | ||
| 50mg | 1,838.00 € | ||
| 100mg | 2,320.00 € | ||
| 500mg | 4,568.00 € | ||
| 1mL*10mM (DMSO) | 881.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Orbofiban TFA
CAS:167833-83-2
Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet …
Formula:
C19H24F3N5O6
Purity:
97.45% - 98.43%
Color and Shape:
Liquid
Molecular weight:
475.42
Ref: TM-T61345L
| 1mg | 277.00 € | ||
| 5mg | 721.00 € | ||
| 10mg | 980.00 € | ||
| 25mg | 1,467.00 € | ||
| 50mg | 1,966.00 € | ||
| 100mg | 2,680.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Bimosiamose disodium
CAS:187269-60-9
Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin …
Formula:
C46H52Na2O16
Purity:
98%
Color and Shape:
Solid
Molecular weight:
906.88
Ref: TM-T14573
| 25mg | 1,435.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
P8RI acetate
P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.
Formula:
C53H81N13O11
Purity:
99.61%
Color and Shape:
Liquid
Molecular weight:
1076.29
Ref: TM-T39615L
| 1mg | 39.00 € | ||
| 2mg | 50.00 € | ||
| 5mg | 72.00 € | ||
| 10mg | 101.00 € | ||
| 25mg | 174.00 € | ||
| 50mg | 262.00 € | ||
| 100mg | 383.00 € | ||
| 200mg | 545.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
GRGDSPK
CAS:111119-28-9
GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix …
Formula:
C28H49N11O11
Purity:
98%
Color and Shape:
Solid
Molecular weight:
715.76
Ref: TM-T7566
| 1mg | 88.00 € | ||
| 5mg | 330.00 € | ||
| 10mg | 594.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Bersanlimab
CAS:1987854-08-9
Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer …
Purity:
> 95% - > 95%
Color and Shape:
Solid
Molecular weight:
144.22 kDa
Ref: TM-T76927
| 1mg | 324.00 € | ||
| 5mg | 826.00 € | ||
| 10mg | 1,425.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Elarofiban TFA
CAS:198958-89-3
Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for …
Formula:
C26H34F6N4O8
Purity:
100%
Color and Shape:
Soild
Molecular weight:
644.56
Ref: TM-T27250L
| 1mg | 183.00 € | ||
| 5mg | 453.00 € | ||
| 10mg | 648.00 € | ||
| 25mg | 1,011.00 € | ||
| 50mg | 1,395.00 € | ||
| 100mg | 1,844.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
