Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
Found 251 products of "Integrin"
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Integrin-IN-2
CAS:Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.Formula:C27H30N4O3Purity:98%Color and Shape:SolidMolecular weight:458.55IS-741 potassium
CAS:IS-741 potassium is a phospholipase A2 inhibitor.Formula:C15H19F3KN3O3SColor and Shape:SolidMolecular weight:417.49XVA143
CAS:XVA143 is an integrin α/β I-like allosteric antagonist, inhibits LFA-1 (αLβ2 integrin)-dependent firm adhesion, induces extended conformations of integrins.Formula:C25H21Cl2N3O8Purity:99.94%Color and Shape:SolidMolecular weight:562.36GR 144053 trihydrochloride
CAS:platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFormula:C18H30Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:454.82TCS 2314
CAS:TCS 2314, Selective VLA-4 antagonist (IC50=4.4 nM), high clearance/low oral bioavailability, for asthma research.Formula:C28H34N4O6Purity:98%Color and Shape:SolidMolecular weight:522.59BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formula:C26H19Cl2N5O4Purity:98.87%Color and Shape:SolidMolecular weight:536.37Ref: TM-T14676
1mg108.00€5mg264.00€10mg371.00€25mg665.00€50mg874.00€100mg1,063.00€200mg1,423.00€1mL*10mM (DMSO)311.00€BMS-587101
CAS:BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.Formula:C26H20Cl2N4O4SColor and Shape:SolidMolecular weight:555.43CLT-28643
CAS:CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.Formula:C19H17N3O4Purity:99.89%Color and Shape:SolidMolecular weight:351.36L 703014
CAS:L 703014 is an antagonist of the fibrinogen receptor.Formula:C24H34N4O4Purity:98%Color and Shape:SolidMolecular weight:442.55αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).Formula:C28H35F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:672.67Firategrast
CAS:Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFormula:C27H27F2NO6Purity:99.67%Color and Shape:SolidMolecular weight:499.5Ref: TM-TQ0291
1mg44.00€5mg93.00€10mg133.00€25mg268.00€50mg439.00€100mg708.00€200mg964.00€1mL*10mM (DMSO)92.00€Elarofiban
CAS:Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Formula:C22H32N4O4Purity:98.76%Color and Shape:SolidMolecular weight:416.51Gly-Arg-Gly-Asp-Ser TFA
CAS:Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.Formula:C19H31F3N8O11Color and Shape:SolidMolecular weight:604.49αvβ1 integrin-IN-2
CAS:αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.Formula:C29H38N4O4Purity:98%Color and Shape:SolidMolecular weight:506.64Lamifiban
CAS:Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.Formula:C24H28N4O6Purity:98%Color and Shape:SolidMolecular weight:468.5SC-52012
CAS:SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.Formula:C25H30N4O6Purity:97.20%Color and Shape:SolidMolecular weight:482.53L 738167
CAS:L 738167 is a potent antagonist of the long-acting fibrinogen receptor.Formula:C25H34N6O6SColor and Shape:SolidMolecular weight:546.643-Hydroxyxanthone
CAS:3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical veinFormula:C13H8O3Purity:98%Color and Shape:SolidMolecular weight:212.2Bexotegrast HCl
CAS:Bexotegrast (PLN-74809) inhibits αVβ1/αVβ6 integrins, preventing TGF-β1 activation to treat IPF and PSC.Formula:C27H38Cl2N6O3Color and Shape:SolidMolecular weight:565.54ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Formula:C15H11BrN2O2SPurity:99.67%Color and Shape:SolidMolecular weight:363.23Ref: TM-T13147
1mg175.00€5mg371.00€10mg557.00€25mg887.00€50mg1,198.00€100mg1,611.00€500mg3,232.00€1mL*10mM (DMSO)409.00€TAK 029
CAS:TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.Formula:C19H23N5O7Color and Shape:SolidMolecular weight:433.42Teclistamab
CAS:Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.Purity:95%Color and Shape:LiquidMolecular weight:143.64 kDaα7β1 integrin modulator-1
CAS:α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].Formula:C23H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:475.56JNJ-26076713
CAS:JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.Formula:C29H38N4O3Purity:98%Color and Shape:SolidMolecular weight:490.64SB-267268
CAS:SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).Formula:C22H24F3N3O4Purity:98%Color and Shape:SolidMolecular weight:451.44Zaurategrast
CAS:Zaurategrast (CDP323) is an oral α4-integrin antagonist that blocks VCAM-1 interactions and is used to study immune cell trafficking.Formula:C26H25BrN4O3Purity:98%Color and Shape:SolidMolecular weight:521.41Carotegrast
CAS:Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.Formula:C27H24Cl2N4O5Color and Shape:SolidMolecular weight:555.41Tirofiban HCl
CAS:Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.
Formula:C22H37ClN2O5SPurity:98%Color and Shape:SolidMolecular weight:477.06αvβ6 integrin inhibitor 2
CAS:αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.Formula:C21H30N4O3Purity:98%Color and Shape:SolidMolecular weight:386.49Integrin Antagonists 27
CAS:Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.Formula:C24H20N4O5Color and Shape:SolidMolecular weight:444.44L-739758
CAS:L-739758 is a glycoprotein IIb/IIIa inhibitor.Formula:C22H26N4O5S3Color and Shape:SolidMolecular weight:522.66Synstatin (92-119)
CAS:Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFormula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27TC-I 15
CAS:α2β1 integrin inhibitorFormula:C23H28N4O6S2Purity:98%Color and Shape:SolidMolecular weight:520.62BIO-7662
CAS:BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.Formula:C38H48N6O8SPurity:98%Color and Shape:SolidMolecular weight:748.89ATN-161
CAS:ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.Formula:C23H35N9O8SPurity:98%Color and Shape:SolidMolecular weight:597.64Lotrafiban hydrochloride
CAS:Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.Formula:C23H33ClN4O4Color and Shape:SolidMolecular weight:464.99BI-1950
CAS:BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.Formula:C32H26Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:646.5Lotrafiban
CAS:Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.Formula:C23H32N4O4Color and Shape:SolidMolecular weight:428.52Roxifiban acetate
CAS:Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used inFormula:C23H33N5O8Purity:97.91% - 98.36%Color and Shape:SolidMolecular weight:507.54αvβ1 integrin-IN-1
CAS:αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Formula:C26H34N6O6SPurity:99.39% - 99.69%Color and Shape:SolidMolecular weight:558.65Ref: TM-T13473
1mg109.00€5mg260.00€10mg409.00€25mg660.00€50mg888.00€100mg1,224.00€200mg1,648.00€1mL*10mM (DMSO)319.00€6-B345TTQ
CAS:6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.Formula:C22H20BrNO4Color and Shape:SolidMolecular weight:442.303OPN expression inhibitor 1
CAS:OPN expression inhibitor 1 is an osteopontin expression inhibitor used in the study of breast cancer metastasis.Formula:C25H33N3O5Purity:99.78%Color and Shape:SolidMolecular weight:455.55Ref: TM-T62820
1mg126.00€5mg258.00€10mg385.00€25mg695.00€50mg1,009.00€100mg1,314.00€1mL*10mM (DMSO)259.00€α5β1 integrin agonist-1
CAS:α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.Formula:C24H26FN5O9Color and Shape:SolidMolecular weight:547.49SF0166
CAS:SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.Formula:C23H27F2N5O4Color and Shape:SolidMolecular weight:475.49Fradafiban
CAS:Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.Formula:C20H21N3O4Purity:98%Color and Shape:SolidMolecular weight:367.40SR121566A
CAS:SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Formula:C20H25N5O4SPurity:98%Color and Shape:SolidMolecular weight:431.51GSK3335103
CAS:GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.Formula:C27H36FN3O4Color and Shape:SolidMolecular weight:485.59GR 83895
CAS:GR 83895 is an antagonist of prototype fibrinogen receptor.Formula:C29H39N9O8SPurity:98%Color and Shape:SolidMolecular weight:673.74L 734217
CAS:L 734217 is an antagonist of the fibrinogen receptor.Formula:C18H31N3O4Purity:98%Color and Shape:SolidMolecular weight:353.46Zalunfiban dihydrochloride
Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.Formula:C16H20Cl2N8O2SColor and Shape:SolidMolecular weight:459.35Des-ethyl-carafiban
CAS:Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.Formula:C22H23N5O5Color and Shape:SolidMolecular weight:437.448
