Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
Found 275 products for "Integrin".
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Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a mAb targeting CD147 used to study the inhibition mechanisms of viral infection by blocking receptor binding to viralColor and Shape:Odour LiquidForimtamig
Forimtamig (RG-6324) is a bispecific antibody that targets GPRC5D and CD3 T cells. It features a 2 + 1 structure, comprising two high-affinity GPRC5D binding segments and one CD3-binding module. Forimtamig is engineered with a P329G LALA mutation in its Fc domain to prevent Fcγ receptor and C1q binding, while maintaining Fc receptor interaction. Its isotype control corresponds to human IgG1 kappa.Color and Shape:Odour Liquidc(phg-isoDGR-(NMe)k) TFA
C(phg-isoDGR-(NMe)k) TFA is a selective and potent ligand for α5β1-integrin, exhibiting an IC50 of 2.9 nM [1].Formula:C29H42F3N9O9Color and Shape:SolidMolecular weight:717.69MINT1526A
MINT1526A (RG-7594) is a humanized IgG1 monoclonal antibody inhibitor targeting α5β1 integrin, exhibiting significant anti-angiogenic activity. This compound is applicable in cancer research.LXY3
CAS:LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.Formula:C32H43N11O15S2Color and Shape:SolidMolecular weight:885.88αvβ6-BP
αvβ6-BP is a selective αvβ6-binding peptide, useful for research in molecular imaging.Formula:C93H164N34O27Molecular weight:2189.25052αVβ8-IN-1
CAS:αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).Formula:C25H32ClN5O4Color and Shape:White SolidMolecular weight:502.01LT25
CAS:LT25 (compound 17) acts as an agonist for the α5β1 integrin, exhibiting an EC50 value of 9.9 nM.Formula:C15H17N3O5Molecular weight:319.31BGC0222
BGC0222 is a novel Irinotecan prodrug. As a PEG-cRGD conjugated derivative of Irinotecan, BGC0222 enables the slow and steady release of Irinotecan. It binds to the αVβ3 target with an IC50 of 4.25 μM and has an IC50 of 58.7 μM for αVβ5. BGC0222 can induce angiogenesis and demonstrates significant antitumor activity in various tumors.Formula:C1241H2276N64O552Molecular weight:26927.36Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purity:99.57%Color and Shape:SolidMolecular weight:447.48LDV FITC
CAS:fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formula:C69H81N11O17SPurity:98%Color and Shape:SolidMolecular weight:1368.53α2β1 Integrin Ligand Peptide
CAS:The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellularFormula:C14H22N4O9Purity:98%Color and Shape:SolidMolecular weight:390.35Fradafiban hydrochloride
Fradafiban (BIBU-52) is a nonpeptide GPIIb/IIIa antagonist with Kd 148 nM for human platelets.Formula:C20H22ClN3O4Color and Shape:SolidMolecular weight:403.86JNJ-70218902
JNJ-70218902 is a bispecific antibody capable of binding to tumor cells expressing TMEFF2 and CD3 on T cells. It induces an exposure-dependent pro-inflammatory response and targeted tumor cell lysis, and enhances T cell-mediated tumor cell killing (EC50: 1.4 nM). JNJ-70218902 holds significant potential for prostate cancer research.Color and Shape:Odour LiquidEMD-132338
CAS:EMD 132338 is a GPIIb/IIIa antagonist.Formula:C17H23N5O4Color and Shape:SolidMolecular weight:361.4HSDVHK-NH2
CAS:Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.Formula:C30H48N12O9Purity:98%Color and Shape:SolidMolecular weight:720.78PDI-IN-4
PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.Formula:C17H12F3NO2Color and Shape:SolidMolecular weight:319.278AFM15
AFM15 is a humanized monoclonal antibody inhibitor that targets CD3E. It is useful for researching metabolic and immune system disorders, including type 1 diabetes and inflammatory bowel disease (IBD).Color and Shape:Odour LiquidFibronectin CS1 Peptide
CAS:Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.Formula:C38H64N8O15Purity:98%Color and Shape:SolidMolecular weight:872.96Gly-Arg-Gly-Asp-Ser
CAS:Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.Formula:C17H30N8O9Purity:98%Color and Shape:SolidMolecular weight:490.47
