Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
Found 268 products of "Integrin"
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Azelaoyl PAF
CAS:Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.Formula:C33H66NO9PColor and Shape:SolidMolecular weight:651.85Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFormula:C184H284N52O57S8·3C2H4O2Purity:99.51%Color and Shape:SolidMolecular weight:4573.21BT100
BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].Purity:98%Color and Shape:Odour SolidAnti-Mouse CD3 Antibody (17A2)
Anti-Mouse CD3 Antibody (17A2) is an IgG2b class antibody of murine origin targeting CD3 and can be used to study TCR signaling and antigen recognition.Purity:99%Color and Shape:Odour LiquidGPRP
CAS:GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.Formula:C18H31N7O5Color and Shape:White To Off-White PowderMolecular weight:425.48Lifitegrast sodium
CAS:Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Formula:C29H23Cl2N2NaO7SPurity:99.33%Color and Shape:SolidMolecular weight:637.46MK-0429
CAS:MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).Formula:C23H29N5O4Color and Shape:SolidMolecular weight:439.51DOTA-cyclo(RGDfK)
CAS:DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.Formula:C43H67N13O14Color and Shape:SoildMolecular weight:990.07RGD Trifluoroacetate
CAS:RGD Trifluoroacetate is a tripeptide for cell adhesion, effective on 24 integrins, and widely used for synthetic surface binding.Formula:C14H23F3N6O8Purity:98%Color and Shape:SoildMolecular weight:460.367Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formula:C29H41F3N8O9Color and Shape:SolidMolecular weight:702.68Orbofiban
CAS:Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.Formula:C17H23N5O4Color and Shape:SolidMolecular weight:361.4Lifitegrast
CAS:Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
Formula:C29H24Cl2N2O7SPurity:99.39% - 99.66%Color and Shape:SolidMolecular weight:615.48Eptifibatide acetate (148031-34-9 free base)
CAS:Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.Formula:C35H49N11O9S2·xC2H4O2Purity:99.7% - 99.87%Color and Shape:SolidMolecular weight:891.01Cyclo(RADfK)
CAS:Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Formula:C28H43N9O7Purity:>99.99%Color and Shape:SolidMolecular weight:617.7Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purity:97.1% - 99.93%Color and Shape:SolidMolecular weight:558.70Arg-Gly-Asp TFA (99896-85-2(free base))
Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.Formula:C14H23F3N6O8Purity:99.2% - ≥98%Color and Shape:SolidMolecular weight:460.36PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purity:99.14% - 99.75%Color and Shape:SolidMolecular weight:501.5Emvistegrast
CAS:Emvistegrast is a quinolone derivative that acts as an antagonist for the α4β7 integrin.Formula:C35H32F4N6O6Color and Shape:SolidMolecular weight:708.66H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formula:C23H38N10O10Purity:>99.99%Color and Shape:SolidMolecular weight:614.61iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formula:C35H57N13O14S2Purity:98.77%Color and Shape:SolidMolecular weight:948.04
