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Integrin

Integrin

Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.

Found 224 products of "Integrin"

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  • Integrin Antagonists 27

    CAS:
    <p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>
    Formula:C24H20N4O5
    Color and Shape:Solid
    Molecular weight:444.44
  • Lamifiban

    CAS:
    <p>Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.</p>
    Formula:C24H28N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:468.5
  • SC-52012

    CAS:
    <p>SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.</p>
    Formula:C25H30N4O6
    Purity:97.20%
    Color and Shape:Solid
    Molecular weight:482.53
  • Gly-Arg-Gly-Asp-Ser TFA

    CAS:
    <p>Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.</p>
    Formula:C19H31F3N8O11
    Color and Shape:Solid
    Molecular weight:604.49
  • L 738167

    CAS:
    <p>L 738167 is a potent antagonist of the long-acting fibrinogen receptor.</p>
    Formula:C25H34N6O6S
    Color and Shape:Solid
    Molecular weight:546.64
  • L-739758

    CAS:
    <p>L-739758 is a glycoprotein IIb/IIIa inhibitor.</p>
    Formula:C22H26N4O5S3
    Color and Shape:Solid
    Molecular weight:522.66
  • TC-I 15

    CAS:
    <p>α2β1 integrin inhibitor</p>
    Formula:C23H28N4O6S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:520.62
  • α7β1 integrin modulator-1

    CAS:
    <p>α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].</p>
    Formula:C23H29N3O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:475.56
  • BIO-7662

    CAS:
    <p>BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.</p>
    Formula:C38H48N6O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:748.89
  • αvβ1 integrin-IN-2

    CAS:
    <p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>
    Formula:C29H38N4O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.64
  • Lotrafiban hydrochloride

    CAS:
    <p>Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.</p>
    Formula:C23H33ClN4O4
    Color and Shape:Solid
    Molecular weight:464.99
  • ATN-161

    CAS:
    <p>ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.</p>
    Formula:C23H35N9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:597.64
  • Roxifiban acetate

    CAS:
    <p>Roxifiban acetate(DMP 754 acetate) is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used in</p>
    Formula:C23H33N5O8
    Purity:97.91% - 98.36%
    Color and Shape:Solid
    Molecular weight:507.54
  • αvβ1 integrin-IN-1

    CAS:
    <p>αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.</p>
    Formula:C26H34N6O6S
    Purity:99.74% - >99.99%
    Color and Shape:Solid
    Molecular weight:558.65
  • α5β1 integrin agonist-1

    CAS:
    <p>α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.</p>
    Formula:C24H26FN5O9
    Color and Shape:Solid
    Molecular weight:547.49
  • SF0166

    CAS:
    <p>SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.</p>
    Formula:C23H27F2N5O4
    Color and Shape:Solid
    Molecular weight:475.49
  • SR121566A

    CAS:
    <p>SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).</p>
    Formula:C20H25N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:431.51
  • Zalunfiban dihydrochloride


    <p>Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.</p>
    Formula:C16H20Cl2N8O2S
    Color and Shape:Solid
    Molecular weight:459.35
  • 6-B345TTQ

    CAS:
    <p>6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.</p>
    Formula:C22H20BrNO4
    Color and Shape:Solid
    Molecular weight:442.303
  • Des-ethyl-carafiban

    CAS:
    <p>Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.</p>
    Formula:C22H23N5O5
    Color and Shape:Solid
    Molecular weight:437.448
  • L 734217

    CAS:
    <p>L 734217 is an antagonist of the fibrinogen receptor.</p>
    Formula:C18H31N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:353.46
  • GSK3335103

    CAS:
    <p>GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.</p>
    Formula:C27H36FN3O4
    Color and Shape:Solid
    Molecular weight:485.59
  • Fradafiban

    CAS:
    <p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>
    Formula:C20H21N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:367.40
  • GR 83895

    CAS:
    <p>GR 83895 is an antagonist of prototype fibrinogen receptor.</p>
    Formula:C29H39N9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:673.74