Integrin
Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.
Found 224 products of "Integrin"
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Vibecotamab
CAS:<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Color and Shape:LiquidObrindatamab
CAS:<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Color and Shape:LiquidPacanalotamab
CAS:<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Color and Shape:LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Purity:95%Color and Shape:Odour LiquidAnti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Purity:99%Color and Shape:Odour LiquidGresonitamab
CAS:<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Color and Shape:LiquidSB273005
CAS:<p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>Formula:C22H24F3N3O4Purity:99.58%Color and Shape:SolidMolecular weight:451.44Tirofiban
CAS:<p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>Formula:C22H36N2O5SPurity:99.83%Color and Shape:SolidMolecular weight:440.6GR 144053 trihydrochloride
CAS:<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Formula:C18H30Cl3N5O2Purity:98%Color and Shape:SolidMolecular weight:454.82Sibrafiban
CAS:<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formula:C20H28N4O6Color and Shape:SolidMolecular weight:420.46UR-3216
CAS:<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Formula:C27H29N7O7Purity:98%Color and Shape:SolidMolecular weight:563.56L 703014
CAS:<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Formula:C24H34N4O4Purity:98%Color and Shape:SolidMolecular weight:442.55Balamapimod
CAS:<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formula:C30H32ClN7OSPurity:98%Color and Shape:SolidMolecular weight:574.14BMS-587101
CAS:<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formula:C26H20Cl2N4O4SColor and Shape:SolidMolecular weight:555.43BMS-688521
CAS:<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Formula:C26H19Cl2N5O4Purity:98.87%Color and Shape:SolidMolecular weight:536.37MK-0668
CAS:<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Formula:C31H30Cl2N6O6SColor and Shape:SolidMolecular weight:685.58NSC47924
CAS:<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Formula:C18H17NO2Purity:98%Color and Shape:SolidMolecular weight:279.33Zalunfiban
CAS:<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Formula:C16H18N8O2SColor and Shape:SolidMolecular weight:386.43TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formula:C28H34N4O6Purity:98%Color and Shape:SolidMolecular weight:522.59Chrysotobibenzyl
CAS:<p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>Formula:C19H24O5Color and Shape:SolidMolecular weight:332.39αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formula:C28H35F3N6O8SPurity:98%Color and Shape:SolidMolecular weight:672.67Zaurategrast ethyl ester sulfate
CAS:<p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>Formula:C56H60Br2N8O10SPurity:98%Color and Shape:SolidMolecular weight:1197.01RUC-1
CAS:<p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>Formula:C11H15N5OSPurity:98%Color and Shape:SolidMolecular weight:265.33Zaurategrast ethyl ester
CAS:<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Formula:C28H29BrN4O3Purity:98%Color and Shape:SolidMolecular weight:549.46IMB-10
CAS:<p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>Formula:C19H15NOS2Color and Shape:SolidMolecular weight:337.46Ro 43-5054
CAS:<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Formula:C24H27N5O7Purity:98%Color and Shape:SolidMolecular weight:497.5BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formula:C25H29N3NaO7SColor and Shape:SolidMolecular weight:538.57GSK-3008348
CAS:<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Formula:C29H37N5O2Purity:99.547%Color and Shape:SolidMolecular weight:487.64Valategrast
CAS:<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Formula:C30H32Cl3N3O4Purity:98%Color and Shape:SolidMolecular weight:604.95Valategrast hydrochloride
CAS:<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Formula:C30H33Cl4N3O4Purity:98%Color and Shape:SolidMolecular weight:641.41CLT-28643
CAS:<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Formula:C19H17N3O4Purity:99.89%Color and Shape:SolidMolecular weight:351.36Integrin-IN-2
CAS:<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Formula:C27H30N4O3Purity:98%Color and Shape:SolidMolecular weight:458.55XVA143
CAS:<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Formula:C25H21Cl2N3O8Color and Shape:SolidMolecular weight:562.36Integrin modulator 1
CAS:<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Formula:C13H14N2O4Purity:99.61%Color and Shape:SolidMolecular weight:262.26Firategrast
CAS:<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Formula:C27H27F2NO6Purity:99.16%Color and Shape:SolidMolecular weight:499.5Elarofiban
CAS:<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Formula:C22H32N4O4Purity:98.76%Color and Shape:SolidMolecular weight:416.513-Hydroxyxanthone
CAS:<p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>Formula:C13H8O3Purity:98%Color and Shape:SolidMolecular weight:212.2ICAM-1-IN-1
CAS:<p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>Formula:C15H11BrN2O2SPurity:99.67%Color and Shape:SolidMolecular weight:363.23BI-1950
CAS:<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Formula:C32H26Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:646.5Teclistamab
CAS:<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Purity:95%Color and Shape:LiquidSynstatin (92-119)
CAS:<p>Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and</p>Formula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27TAK 029
CAS:<p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>Formula:C19H23N5O7Color and Shape:SolidMolecular weight:433.42αvβ6 integrin inhibitor 2
CAS:<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Formula:C21H30N4O3Purity:98%Color and Shape:SolidMolecular weight:386.49Lotrafiban
CAS:<p>Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.</p>Formula:C23H32N4O4Color and Shape:SolidMolecular weight:428.52JNJ-26076713
CAS:<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Formula:C29H38N4O3Purity:98%Color and Shape:SolidMolecular weight:490.64SB-267268
CAS:<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Formula:C22H24F3N3O4Purity:98%Color and Shape:SolidMolecular weight:451.44Zaurategrast
CAS:<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Formula:C26H25BrN4O3Purity:98%Color and Shape:SolidMolecular weight:521.41Solitomab
CAS:<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Color and Shape:LiquidCarotegrast
CAS:<p>Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.</p>Formula:C27H24Cl2N4O5Color and Shape:SolidMolecular weight:555.41Tirofiban HCl
CAS:<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Formula:C22H37ClN2O5SPurity:98%Color and Shape:SolidMolecular weight:477.06
