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Integrin

Integrin

Integrin inhibitors target integrins, a family of cell surface receptors that play a crucial role in cell adhesion, migration, and signal transduction. Integrins are involved in the regulation of the cell cycle, particularly in processes such as cell division and differentiation. Inhibiting integrins can disrupt these processes, leading to cell cycle arrest and apoptosis, making these inhibitors valuable in cancer research and the study of metastasis. At CymitQuimica, we offer a wide range of high-quality integrin inhibitors to support your research in cell cycle regulation, cancer biology, and therapeutic development.

Found 224 products of "Integrin"

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  • CLT-28643
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    CLT-28643

    CAS:
    <p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>
    Formula:C19H17N3O4
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:351.36

    Ref: TM-T71368

  • Integrin-IN-2
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    Integrin-IN-2

    CAS:
    <p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>
    Formula:C27H30N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:458.55

    Ref: TM-T11663

  • XVA143
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    XVA143

    CAS:
    <p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>
    Formula:C25H21Cl2N3O8
    Color and Shape:Solid
    Molecular weight:562.36

    Ref: TM-T40274

  • Integrin modulator 1
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    Integrin modulator 1

    CAS:
    <p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>
    Formula:C13H14N2O4
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:262.26

    Ref: TM-T36291

  • Firategrast
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    Firategrast

    CAS:
    <p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>
    Formula:C27H27F2NO6
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:499.5

    Ref: TM-TQ0291

  • Elarofiban
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    Elarofiban

    CAS:
    <p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>
    Formula:C22H32N4O4
    Purity:98.76%
    Color and Shape:Solid
    Molecular weight:416.51

    Ref: TM-T27250

  • 3-Hydroxyxanthone
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    3-Hydroxyxanthone

    CAS:
    <p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>
    Formula:C13H8O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:212.2

    Ref: TM-T78548

  • ICAM-1-IN-1
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    ICAM-1-IN-1

    CAS:
    <p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>
    Formula:C15H11BrN2O2S
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:363.23

    Ref: TM-T13147

  • BI-1950
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    BI-1950

    CAS:
    <p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>
    Formula:C32H26Cl2FN7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:646.5

    Ref: TM-T14558

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    Teclistamab

    CAS:
    <p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>
    Purity:95%
    Color and Shape:Liquid

    Ref: TM-T76881

  • Synstatin (92-119)
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    Synstatin (92-119)

    CAS:
    <p>Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and</p>
    Formula:C133H207N35O46
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3032.27

    Ref: TM-T78064

  • TAK 029
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    TAK 029

    CAS:
    <p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>
    Formula:C19H23N5O7
    Color and Shape:Solid
    Molecular weight:433.42

    Ref: TM-T28913

  • αvβ6 integrin inhibitor 2
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    αvβ6 integrin inhibitor 2

    CAS:
    <p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>
    Formula:C21H30N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:386.49

    Ref: TM-T79140

  • Lotrafiban
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    Lotrafiban

    CAS:
    <p>Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.</p>
    Formula:C23H32N4O4
    Color and Shape:Solid
    Molecular weight:428.52

    Ref: TM-T62351

  • JNJ-26076713
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    JNJ-26076713

    CAS:
    <p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>
    Formula:C29H38N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:490.64

    Ref: TM-T27670

  • SB-267268
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    SB-267268

    CAS:
    <p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>
    Formula:C22H24F3N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:451.44

    Ref: TM-T16851

  • Zaurategrast
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    Zaurategrast

    CAS:
    <p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>
    Formula:C26H25BrN4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:521.41

    Ref: TM-T17286

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    Solitomab

    CAS:
    <p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>
    Color and Shape:Liquid

    Ref: TM-T76996

  • Carotegrast
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    Carotegrast

    CAS:
    <p>Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.</p>
    Formula:C27H24Cl2N4O5
    Color and Shape:Solid
    Molecular weight:555.41

    Ref: TM-T14876

  • Tirofiban HCl
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    Tirofiban HCl

    CAS:
    <p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>
    Formula:C22H37ClN2O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:477.06

    Ref: TM-T20552