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Ferroptosis

Ferroptosis

Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.

Found 215 products of "Ferroptosis"

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  • W1131
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    W1131

    CAS:
    <p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>
    Formula:C23H19N5O4
    Color and Shape:Solid
    Molecular weight:429.43

    Ref: TM-T73558

  • YL-939
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    YL-939

    <p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>
    Formula:C25H26N6O
    Color and Shape:Solid
    Molecular weight:426.51

    Ref: TM-T73513

  • Ferroptosis inducer-1
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    Ferroptosis inducer-1

    CAS:
    <p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>
    Formula:C25H21ClN2O5
    Color and Shape:Solid
    Molecular weight:464.9

    Ref: TM-T72403

  • CN128 hydrochloride
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    CN128 hydrochloride

    CAS:
    <p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>
    Formula:C15H18ClNO3
    Color and Shape:Solid
    Molecular weight:295.76

    Ref: TM-T9302

  • Anticancer agent 147
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    Anticancer agent 147

    CAS:
    <p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>
    Formula:C32H40BrN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:578.58

    Ref: TM-T79359

  • Tubulin inhibitor 30
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    Tubulin inhibitor 30

    CAS:
    <p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>
    Formula:C22H19N3O5
    Color and Shape:Solid
    Molecular weight:405.4

    Ref: TM-T72445

  • IM-93
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    IM-93

    CAS:
    <p>IM-93 inhibits ferroptosis and NETosis with an IC&lt; sub&gt;50 of 0.45 μM for cell death inhibition [1].</p>
    Formula:C21H28N4O2
    Color and Shape:Solid
    Molecular weight:368.47

    Ref: TM-T61450

  • CGP 65015
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    CGP 65015

    CAS:
    <p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>
    Formula:C14H15NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:261.27

    Ref: TM-T13607

  • FA16
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    FA16

    <p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>
    Formula:C22H27F3N4O2S
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:468.54

    Ref: TM-T64357

  • Deferitazole
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    Deferitazole

    CAS:
    <p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>
    Formula:C18H25NO7S
    Purity:99.48%
    Color and Shape:Solid
    Molecular weight:399.46

    Ref: TM-T31362

  • Erastin2
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    Erastin2

    CAS:
    <p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>
    Formula:C36H35ClN4O4
    Purity:99.63%
    Color and Shape:Solid
    Molecular weight:623.14

    Ref: TM-T35994

  • HBED
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    HBED

    CAS:
    <p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>
    Formula:C20H24N2O6
    Purity:97.35% - 98.58%
    Color and Shape:Solid
    Molecular weight:388.41

    Ref: TM-T32046

  • BCP-T.A
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    BCP-T.A

    CAS:
    <p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>
    Formula:C23H19Cl2N3OS
    Purity:99.49%
    Color and Shape:Solid
    Molecular weight:456.39

    Ref: TM-T62827

  • Lepadin E
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    Lepadin E

    CAS:
    <p>Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.</p>
    Formula:C26H47NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.66

    Ref: TM-T79638

  • CP-24879 hydrochloride
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    CP-24879 hydrochloride

    CAS:
    <p>CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.</p>
    Formula:C11H18ClNO
    Purity:98.08%
    Color and Shape:Solid
    Molecular weight:215.72

    Ref: TM-T27061

  • Docebenone
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    Docebenone

    CAS:
    <p>Docebenone is a selective and orally active inhibitor of 5-LO.</p>
    Formula:C21H26O3
    Color and Shape:Solid
    Molecular weight:326.43

    Ref: TM-T15155

  • Ferroptocide
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    Ferroptocide

    CAS:
    <p>Ferroptocide is a thioredoxin inhibitor that induces iron death in cancer cells and can be used in breast cancer research.</p>
    Formula:C30H36ClN3O7
    Color and Shape:Solid
    Molecular weight:586.08

    Ref: TM-T83871

  • Ogremorphin
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    Ogremorphin

    CAS:
    <p>Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1</p>
    Formula:C21H17N3OS
    Purity:99.65% - 99.65%
    Color and Shape:Solid
    Molecular weight:359.44

    Ref: TM-T79209

  • Lepadin H
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    Lepadin H

    CAS:
    <p>Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing</p>
    Formula:C26H45NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:419.64

    Ref: TM-T79639

  • viFSP1
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    viFSP1

    CAS:
    <p>viFSP1, a species-independent FSP1 inhibitor, effectively induces ferroptosis in FSP1-dependent cells by targeting the highly conserved NAD(P)H binding pocket of FSP1, directly inhibiting its activity. This action results in lipid peroxidation and exhibits anticancer activity [1].</p>
    Formula:C16H17N3O3S
    Color and Shape:Solid
    Molecular weight:331.39

    Ref: TM-T84823