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Ferroptosis

Ferroptosis

Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid peroxides and iron-dependent oxidative stress. Unlike apoptosis, ferroptosis is not driven by caspases but rather by the failure of cellular antioxidant defenses, leading to cell death. Ferroptosis inhibitors and inducers are critical for studying this unique cell death pathway, which is implicated in various diseases, including cancer, neurodegeneration, and ischemia-reperfusion injury. At CymitQuimica, we offer a wide range of high-quality ferroptosis modulators to support your research in cell death mechanisms, oxidative stress, and disease pathology.

Found 226 products of "Ferroptosis"

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  • Cetzole

    CAS:
    Cetzole (Compound 1) acts as an inducer of ferroptosis (iron-dependent cell death) through the accumulation of ROS, leading to cell death. The compound exhibits varying half-maximal cytotoxic concentrations (CC50) against several cell lines: 2.56 μM in NCI-H522, 10.31 μM in NCI-H522 GFP-SCL7A11 #8, 2.71 μM in NCI-H522 RV-GFP, 3.07 μM in HT-1080, 14.9 μM in NARF2, and 6.28 μM in MDA-MB-231. This highlights Cetzole's potential for research in cancer therapeutics.
    Formula:C11H11NOS
    Color and Shape:Solid
    Molecular weight:205.28

    Ref: TM-T200746

    25mg
    1,539.00€
    50mg
    1,941.00€
    100mg
    2,451.00€
  • TfR-1-IN-1

    CAS:
    TfR-1-IN-1 is a TfR-1 inhibitor, also a Fe(III) salivary phenol complex, inducing apoptosis and inhibiting tumor and normal cell growth.
    Formula:C20H12ClF2FeN2O2
    Purity:96.96%
    Color and Shape:Solid
    Molecular weight:441.62

    Ref: TM-T89857

    1mg
    665.00€
  • Microtubule inhibitor 2


    Microtubule inhibitor 2: potent, selective, oral, induces ferroptosis, strong antitumor effect.
    Formula:C20H23NO7
    Color and Shape:Solid
    Molecular weight:389.4

    Ref: TM-T61749

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • NPB-1575

    CAS:
    NPB-1575 is a potent, orally active anti-inflammatory agent capable of crossing the blood-brain barrier. It mitigates neuroinflammation and resists ferroptosis by activating IRS2/Nrf2/NF-κB. NPB-1575 protects against cerebral ischemic injury and improves neurological function outcomes, making it suitable for research in focal ischemic stroke.
    Formula:C19H22O4
    Color and Shape:Solid
    Molecular weight:314.38

    Ref: TM-T210796

    10mg
    To inquire
    50mg
    To inquire
  • PRGL493

    CAS:
    PRGL493 blocks ACSL4, halts PC3/MDA-MB-231 cancer cell spread, and inhibits MA-10 tumor progesterone. Effective in mouse PC3 tumor model at 0.25 mg/kg.
    Formula:C25H21N7O2
    Purity:98.80% - 99.11%
    Color and Shape:Solid
    Molecular weight:451.48

    Ref: TM-T35666

    1mg
    Discontinued
    5mg
    Discontinued
    10mg
    Discontinued
    25mg
    Discontinued
    50mg
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    100mg
    Discontinued
    Discontinued product
  • Vatiquinone

    CAS:
    Vatiquinone, also known as EPI 743, is an orally bioavailable para-benzoquinone being developed for inherited mitochondrial diseases. The mechanism of action of EPI-743 involves augmenting the synthesis of glutathione, optimizing metabolic control, enhanc
    Formula:C29H44O3
    Color and Shape:Solid
    Molecular weight:440.66

    Ref: TM-T35040

    ne
    Discontinued
    Discontinued product