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CDK

CDK

CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.

Found 500 products of "CDK"

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  • MLS-573151
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    MLS-573151

    CAS:
    <p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>
    Formula:C21H19N3O2S
    Purity:98.80%
    Color and Shape:Solid
    Molecular weight:377.46

    Ref: TM-T22106

  • AZD-5597
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    AZD-5597

    CAS:
    <p>AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent</p>
    Formula:C23H28FN7O
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:437.51

    Ref: TM-T21544

  • SEL120-34A HCl
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    SEL120-34A HCl

    CAS:
    <p>SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectively</p>
    Formula:C15H19Br2ClN4
    Purity:98.13% - 98.47%
    Color and Shape:Solid
    Molecular weight:450.6

    Ref: TM-T10744L

  • AS2863619
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    AS2863619

    CAS:
    <p>AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.</p>
    Formula:C16H14Cl2N8O
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:405.24

    Ref: TM-T8378

  • Longdaysin
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    Longdaysin

    CAS:
    <p>Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).</p>
    Formula:C16H16F3N5
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:335.33

    Ref: TM-T5358

  • Briciclib
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    Briciclib

    CAS:
    <p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>
    Formula:C19H23O10PS
    Purity:98% - 99.84%
    Color and Shape:Solid
    Molecular weight:474.42

    Ref: TM-T3207

  • 6-(Dimethylamino)purine
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    6-(Dimethylamino)purine

    CAS:
    <p>6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor</p>
    Formula:C7H9N5
    Purity:99.01% - 99.77%
    Color and Shape:Solid
    Molecular weight:163.18

    Ref: TM-T7444

  • AT7519 TFA
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    AT7519 TFA

    CAS:
    <p>AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.</p>
    Formula:C18H18Cl2F3N5O4
    Color and Shape:Solid
    Molecular weight:496.27

    Ref: TM-T22590

  • LDC000067
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    LDC000067

    CAS:
    <p>LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.</p>
    Formula:C18H18N4O3S
    Purity:98.08% - 99.07%
    Color and Shape:Solid
    Molecular weight:370.43

    Ref: TM-T6563

  • Senexin B
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    Senexin B

    CAS:
    <p>Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).</p>
    Formula:C27H26N6O
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:450.53

    Ref: TM-T8430

  • THZ1
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    THZ1

    CAS:
    <p>THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.</p>
    Formula:C31H28ClN7O2
    Purity:95.09% - 99.27%
    Color and Shape:Solid
    Molecular weight:566.05

    Ref: TM-T3664

  • CKI-7
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    CKI-7

    CAS:
    <p>CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>
    Formula:C11H14Cl3N3O2S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:358.67

    Ref: TM-T19913

  • M2N12
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    M2N12

    CAS:
    <p>M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.</p>
    Formula:C20H16ClN5O2
    Purity:98.01%
    Color and Shape:Solid
    Molecular weight:393.83

    Ref: TM-T11929

  • Aminopurvalanol A
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    Aminopurvalanol A

    CAS:
    <p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>
    Formula:C19H26ClN7O
    Purity:99.73%
    Color and Shape:Solid
    Molecular weight:403.91

    Ref: TM-T22260

  • Cdk5 Substrate acetate
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    Cdk5 Substrate acetate

    <p>Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.</p>
    Formula:C55H103N15O14
    Purity:96.21%
    Color and Shape:Solid
    Molecular weight:1198.5

    Ref: TM-T37207L

  • THAL-SNS-032
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    THAL-SNS-032

    CAS:
    <p>THAL-SNS-032 is a selective CDK9 degrader PROTAC.</p>
    Formula:C40H52N8O10S2
    Purity:99.68%
    Color and Shape:Solid
    Molecular weight:869.02

    Ref: TM-T17069

  • CymitQuimica logo
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    Palbociclib dihydrochloride

    <p>Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.</p>
    Formula:C24H31Cl2N7O2
    Color and Shape:Solid
    Molecular weight:520.45

    Ref: TM-T63634

  • OTS964 hydrochloride
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    OTS964 hydrochloride

    CAS:
    <p>OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.</p>
    Formula:C23H24N2O2S·HCl
    Purity:96.5% - 98.03%
    Color and Shape:Solid
    Molecular weight:428.97

    Ref: TM-T4135

  • NG 52
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    NG 52

    CAS:
    <p>NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.</p>
    Formula:C16H19ClN6O
    Purity:98% - 99.34%
    Color and Shape:Solid
    Molecular weight:346.81

    Ref: TM-T2028

  • Bromosporine
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    Bromosporine

    CAS:
    <p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>
    Formula:C17H20N6O4S
    Purity:99.65% - 99.79%
    Color and Shape:Solid
    Molecular weight:404.44

    Ref: TM-T6255