CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Found 546 products of "CDK"
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Fadraciclib
CAS:Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).Formula:C21H31N7OPurity:99.75%Color and Shape:SolidMolecular weight:397.52Ref: TM-TQ0053
1mg42.00€2mg55.00€5mg88.00€10mg145.00€25mg260.00€50mg414.00€100mg583.00€1mL*10mM (DMSO)87.00€BSJ-03-123
CAS:BSJ-03-123 is a potent, CDK6-selective small-molecule degrader.Formula:C47H56N10O11Purity:97.78% - 99.38%Color and Shape:SolidMolecular weight:937.01Ref: TM-T5395
1mg87.00€2mg113.00€5mg177.00€10mg259.00€25mg409.00€50mg560.00€100mg800.00€500mg1,611.00€PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Formula:C20H27F2N5O4SPurity:98.77% - 99.55%Color and Shape:SolidMolecular weight:471.52Ref: TM-T8463
1mg54.00€5mg114.00€10mg178.00€25mg334.00€50mg557.00€100mg888.00€200mg1,198.00€1mL*10mM (DMSO)118.00€THZ531
CAS:THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).Formula:C30H32ClN7O2Purity:97.17% - 99.86%Color and Shape:SolidMolecular weight:558.07Ref: TM-T4293
1mg59.00€2mg86.00€5mg105.00€10mg144.00€25mg313.00€50mg447.00€100mg650.00€500mg1,341.00€1mL*10mM (DMSO)130.00€Bohemine
CAS:Bohemine is a cyclin-dependent kinase inhibitor.Formula:C18H24N6OPurity:99.09% - 99.53%Color and Shape:SolidMolecular weight:340.42(E/Z)-Zotiraciclib citrate
(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.Formula:C29H32N4O8Color and Shape:SolidMolecular weight:564.59ML167
CAS:ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.
Formula:C19H17N3O3Purity:99.82% - >99.99%Color and Shape:SolidMolecular weight:335.36MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Formula:C17H18N4O3SPurity:99.84%Color and Shape:SolidMolecular weight:358.41Ref: TM-T5533
1mg52.00€5mg124.00€10mg177.00€25mg301.00€50mg424.00€100mg605.00€200mg797.00€1mL*10mM (DMSO)136.00€Voruciclib
CAS:Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large B-cell lymphoma.Formula:C22H19ClF3NO5Purity:99.89% - 99.99%Color and Shape:SolidMolecular weight:469.847BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17R547
CAS:R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.Formula:C18H21F2N5O4SPurity:90% - 99.64%Color and Shape:SolidMolecular weight:441.45Ref: TM-T6312
1mg48.00€5mg96.00€10mg140.00€25mg254.00€50mg487.00€100mg700.00€200mg973.00€1mL*10mM (DMSO)114.00€LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
Formula:C23H29ClN8OPurity:100%Color and Shape:SolidMolecular weight:469.026-(Dimethylamino)purine
CAS:6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitorFormula:C7H9N5Purity:99.01% - 99.77%Color and Shape:SolidMolecular weight:163.18Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Formula:C17H14N4Purity:99.74%Color and Shape:SolidMolecular weight:274.32Ref: TM-T5673
1mg34.00€5mg73.00€10mg94.00€25mg177.00€50mg323.00€100mg460.00€200mg622.00€1mL*10mM (DMSO)71.00€AZD-5597
CAS:AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent
Formula:C23H28FN7OPurity:98.01%Color and Shape:SolidMolecular weight:437.51Milciclib
CAS:Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.Formula:C25H32N8OPurity:99.28%Color and Shape:SolidMolecular weight:460.57Ref: TM-T6081
1mg49.00€5mg101.00€10mg168.00€25mg356.00€50mg572.00€100mg858.00€200mg1,153.00€1mL*10mM (DMSO)104.00€JNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formula:C15H12F2N6O3SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:394.36Ref: TM-T6126
1mg48.00€5mg100.00€10mg155.00€25mg268.00€50mg432.00€100mg595.00€200mg833.00€1mL*10mM (DMSO)94.00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formula:C22H25N7O2Purity:97.58% - 99.94%Color and Shape:SolidMolecular weight:419.48BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formula:C22H32N6·HClPurity:99.21%Color and Shape:SolidMolecular weight:416.99Ref: TM-T6162
1mg37.00€2mg52.00€5mg79.00€10mg116.00€25mg250.00€50mg416.00€100mg645.00€200mgTo inquire1mL*10mM (DMSO)87.00€M2N12
CAS:M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.Formula:C20H16ClN5O2Purity:98.01%Color and Shape:SolidMolecular weight:393.83Ref: TM-T11929
1mg84.00€5mg152.00€10mg236.00€25mg447.00€50mg670.00€100mg982.00€1mL*10mM (DMSO)167.00€
