
CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Found 500 products of "CDK"
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Metralindole HCl
CAS:<p>Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.</p>Formula:C15H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:291.78CDK7-IN-15
CAS:<p>CDK7-IN-15, a pyrimidine-based potent CDK7 inhibitor, shows promise for various cancers with defective transcription.</p>Formula:C21H24F4N6OSColor and Shape:SolidMolecular weight:484.51BAY-958
CAS:<p>BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.</p>Formula:C17H16FN5O3SPurity:98%Color and Shape:SolidMolecular weight:389.4EGFR/CDK2-IN-1
CAS:<p>EGFR/CDK2-IN-1, an inhibitor of both EGFR and CDK2, demonstrates effective cytotoxicity towards MCF7 and HepG2 cells, suggesting its potential application in</p>Formula:C19H12BrClO2Color and Shape:SolidMolecular weight:387.65CDK7-IN-10
CAS:<p>CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)</p>Formula:C29H35N7O3Color and Shape:SolidMolecular weight:529.63CDK7-IN-16
CAS:<p>CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.</p>Formula:C19H21F3N6O2SColor and Shape:SolidMolecular weight:454.47Ipivivint
CAS:<p>Ipivivint: orally active, potent CLK inhibitor; hinders CLK1, CLK2, & CLK3; curbs Wnt signaling & SRSF phosphorylation for cancer research.</p>Formula:C26H21FN8Color and Shape:SolidMolecular weight:464.5NSC 693868
CAS:<p>CDKs and GSK-3 inhibitor</p>Formula:C9H7N5Purity:98%Color and Shape:SolidMolecular weight:185.19Atuveciclib S-Enantiomer
CAS:<p>Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.</p>Formula:C18H18FN5O2SPurity:98%Color and Shape:SolidMolecular weight:387.43CDK8-IN-6
CAS:<p>CDK8-IN-6 (compound 9) is a potent inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 13 nM), CDK8-IN-6 showed potential research value in AML cancers.</p>Formula:C26H37ClN2Color and Shape:SolidMolecular weight:413.04CDK4/6-IN-14
CAS:<p>CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.</p>Formula:C24H27ClFN7OColor and Shape:SolidMolecular weight:483.97KH-CB19
CAS:<p>KH-CB19 is an effective and highly specific inhibitor of the CDC2-like kinase isoforms 1 and 4 (CLK1/CLK4).</p>Formula:C15H13Cl2N3O2Color and Shape:SolidMolecular weight:338.19Cdc7-IN-14
CAS:<p>Cdc7-IN-14 (compound 82) is a potent CDC7 inhibitor with an IC50 < 1 nM, promising for cancer research.</p>Formula:C18H20N4O2SColor and Shape:SolidMolecular weight:356.44CDK9-IN-15
CAS:<p>CDK9-IN-15: potent CDK9 inhibitor, blocks P-TEFb phosphorylation, inhibits transcription, reduces mRNA, induces tumor cell apoptosis.</p>Formula:C16H11N3OSPurity:97.24%Color and Shape:SolidMolecular weight:293.34CDK-IN-10
CAS:<p>CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.</p>Formula:C18H18N4O2Purity:97.07%Color and Shape:SolidMolecular weight:322.36CLK1-IN-2
<p>CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.</p>Formula:C16H12Cl2N2O2SColor and Shape:SolidMolecular weight:367.25XIE18-6
CAS:<p>XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.</p>Formula:C18H15NO6SPurity:99.712%Color and Shape:SolidMolecular weight:373.38NSC 625987
CAS:<p>Cyclin-dependent kinase (cdk) 4 inhibitor</p>Formula:C15H13NO2SPurity:98%Color and Shape:SolidMolecular weight:271.33ARN22089
CAS:<p>ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.</p>Formula:C23H27N5Purity:98.37%Color and Shape:SolidMolecular weight:373.49CDK8/19-IN-51
CAS:<p>CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.</p>Formula:C23H22N6O2Purity:98.65% - 99.62%Color and Shape:SoildMolecular weight:414.46
