
CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Found 501 products of "CDK"
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K 00546
CAS:<p>K00546 inhibits CDK1/cyclin B (IC50: 0.6 nM), CDK2/cyclin A (IC50: 0.5 nM), CLK1 (IC50: 8.9 nM), and CLK3 (IC50: 29.2 nM).</p>Formula:C15H13F2N7O2S2Purity:99.12%Color and Shape:SolidMolecular weight:425.44SNX2-1-108
CAS:<p>SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.</p>Formula:C21H16N4Purity:98%Color and Shape:SolidMolecular weight:324.38Metralindole HCl
CAS:<p>Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.</p>Formula:C15H18ClN3OPurity:98%Color and Shape:SolidMolecular weight:291.78CDK8-IN-7
CAS:<p>CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.</p>Formula:C30H40N2Color and Shape:SolidMolecular weight:428.65BAY-958
CAS:<p>BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.</p>Formula:C17H16FN5O3SPurity:98%Color and Shape:SolidMolecular weight:389.4Atuveciclib S-Enantiomer
CAS:<p>Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.</p>Formula:C18H18FN5O2SPurity:98%Color and Shape:SolidMolecular weight:387.43Cdc7-IN-15
CAS:<p>Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].</p>Formula:C12H14N4OSColor and Shape:SolidMolecular weight:262.33CP681301
CAS:<p>CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.</p>Formula:C17H22N4OColor and Shape:SolidMolecular weight:298.38(E/Z)-BIO-acetoxime
CAS:<p>(E/Z)-BIO-acetoxime: potent GSK-3 α/β inhibitor; IC50: GSK-3α/β 10nM, CDK5/p25 2.4μM, CDK2/A 4.3μM, CDK1/B 63μM.</p>Formula:C18H12BrN3O3Color and Shape:SolidMolecular weight:398.21CDK-IN-10
CAS:<p>CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.</p>Formula:C18H18N4O2Purity:97.07%Color and Shape:SolidMolecular weight:322.36CDK8-IN-4
CAS:<p>CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).</p>Formula:C20H18N4OColor and Shape:SolidMolecular weight:330.38CDK12-IN-3
CAS:<p>CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.</p>Formula:C23H28F2N8OPurity:99.85%Color and Shape:SolidMolecular weight:470.52NSC 693868
CAS:<p>CDKs and GSK-3 inhibitor</p>Formula:C9H7N5Purity:98%Color and Shape:SolidMolecular weight:185.19P18IN003
CAS:<p>P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion of</p>Formula:C17H16N2O3Purity:98.77%Color and Shape:SolidMolecular weight:296.32CDK7-IN-15
CAS:<p>CDK7-IN-15, a pyrimidine-based potent CDK7 inhibitor, shows promise for various cancers with defective transcription.</p>Formula:C21H24F4N6OSColor and Shape:SolidMolecular weight:484.51Cdc7-IN-1
CAS:<p>Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.</p>Formula:C21H16ClN3O4Color and Shape:SolidMolecular weight:409.82BS-181
CAS:<p>BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.</p>Formula:C22H32N6Purity:98%Color and Shape:SolidMolecular weight:380.53CLK1/2-IN-3
CAS:<p>CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.</p>Formula:C21H21N5O2Purity:99.04%Color and Shape:SolidMolecular weight:375.42CDK7-IN-10
CAS:<p>CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)</p>Formula:C29H35N7O3Color and Shape:SolidMolecular weight:529.63CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Formula:C18H18ClN5OPurity:98.81%Color and Shape:SolidMolecular weight:355.82
