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CDK

CDK

CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.

Found 500 products of "CDK"

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  • RP-106
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    RP-106

    CAS:
    <p>RP-106 is an ATP-competitive inhibitor of CDK5/p25, CDK1/cyclin B, and GSK-3.</p>
    Formula:C17H19N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.35

    Ref: TM-T24734

  • PKC-9
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    PKC-9

    CAS:
    <p>PKC-9 is a PKC-zeta inhibitor 9.</p>
    Formula:C25H25N7
    Color and Shape:Solid
    Molecular weight:423.51

    Ref: TM-T71993

  • CDK4/6-IN-7
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    CDK4/6-IN-7

    CAS:
    <p>CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.</p>
    Formula:C18H18ClN5O3
    Color and Shape:Solid
    Molecular weight:387.82

    Ref: TM-T61738

  • Cdc7-IN-3
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    Cdc7-IN-3

    CAS:
    <p>Cdc7-IN-3 is a potent inhibitor of Cdc7 kinase.</p>
    Formula:C20H22N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:398.41

    Ref: TM-T10725

  • CDK7-IN-2
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    CDK7-IN-2

    CAS:
    <p>CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.</p>
    Formula:C26H39N7O3
    Color and Shape:Solid
    Molecular weight:497.63

    Ref: TM-T63368

  • EGFR/HER2/CDK9-IN-1
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    EGFR/HER2/CDK9-IN-1

    CAS:
    <p>EGFR/HER2/CDK9-IN-1 is a potent inhibitor (IC50: EGFR 90.17 nM, HER2 131.39 nM, CDK9 67.04 nM) with notable anti-tumor activity.</p>
    Formula:C23H21N3O3S2
    Color and Shape:Solid
    Molecular weight:451.56

    Ref: TM-T62746

  • CDK5 inhibitor 20-223
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    CDK5 inhibitor 20-223

    CAS:
    <p>CDK5 inhibitor 20-223 is a potent CDK2/CDK5 inhibitor,anti-Colorectal Cancer (CRC), inhibiting cell migration and inducing cell cycle arrest.</p>
    Formula:C19H19N3O
    Color and Shape:Solid
    Molecular weight:305.37

    Ref: TM-T36742

  • FN-1501-propionic acid
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    FN-1501-propionic acid

    CAS:
    <p>FN-1501-propionic acid, a CDK2/9 ligand, in conjunction with a CRBN ligand, has been utilized in the design of a PROTAC CDK2/9 degrader.</p>
    Formula:C25H27N9O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:517.54

    Ref: TM-T13696

  • EGFR/HER2/CDK9-IN-2
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    EGFR/HER2/CDK9-IN-2

    CAS:
    <p>EGFR/HER2/CDK9-IN-2 inhibits EGFR, HER2, CDK9 with IC50s: 145.35, 129.07, 117.13 nM; strong antitumor effects.</p>
    Formula:C23H20N4O5S2
    Color and Shape:Solid
    Molecular weight:496.56

    Ref: TM-T63357

  • CDK8-IN-10
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    CDK8-IN-10

    CAS:
    <p>CDK8-IN-10 is a selective and potent inhibitor of cell cycle protein-dependent kinase (CDK8) (IC50: 8.25 nM) that can be used to study cancer.</p>
    Formula:C25H15ClF3N5O3
    Color and Shape:Solid
    Molecular weight:525.87

    Ref: TM-T63690

  • CDK4/6-IN-8
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    CDK4/6-IN-8

    CAS:
    <p>CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 (IC50=5.01 nM) and CDK6 (IC50=3.97 nM).</p>
    Formula:C18H18N6O5
    Color and Shape:Solid
    Molecular weight:398.37

    Ref: TM-T61892

  • AS-0141
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    AS-0141

    CAS:
    <p>AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM)，具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶，在细胞周期中对 DNA 复制的启动至关重要。</p>
    Formula:C21H22F3N5O4
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:465.43

    Ref: TM-T10728

  • Ryuvidine
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    Ryuvidine

    CAS:
    <p>Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response, and can be used to study breast cancer and erythroderma.</p>
    Formula:C15H12N2O2S
    Purity:98.6%
    Color and Shape:Solid
    Molecular weight:284.33

    Ref: TM-T23284

  • (S)-Enitociclib
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    (S)-Enitociclib

    CAS:
    <p>(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.</p>
    Formula:C19H18F2N4O2S
    Purity:98.98%
    Color and Shape:Solid
    Molecular weight:404.43

    Ref: TM-T70388

  • CLK-IN-T3
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    CLK-IN-T3

    CAS:
    <p>CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.</p>
    Formula:C28H30N6O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:482.58

    Ref: TM-T14980

  • (S)-PF-06873600
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    (S)-PF-06873600

    CAS:
    <p>(S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.</p>
    Formula:C20H27F2N5O4S
    Purity:98.59%
    Color and Shape:Solid
    Molecular weight:471.52

    Ref: TM-T12809

  • CDK9-IN-10
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    CDK9-IN-10

    CAS:
    <p>CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.</p>
    Formula:C22H16O5
    Purity:99.8%
    Color and Shape:Solid
    Molecular weight:360.36

    Ref: TM-T10742

  • PS423
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    PS423

    CAS:
    <p>PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.</p>
    Formula:C25H23F3O9
    Purity:98.81% - 99.26%
    Color and Shape:Solid
    Molecular weight:524.44

    Ref: TM-T24676

  • HTH-01-091
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    HTH-01-091

    CAS:
    <p>HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,</p>
    Formula:C26H28Cl2N4O2
    Purity:98.4%
    Color and Shape:Solid
    Molecular weight:499.43

    Ref: TM-T24152

  • hSMG-1 inhibitor 11e
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    hSMG-1 inhibitor 11e

    CAS:
    <p>hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 &lt;0.05 nM) and can be used in studies about cancer treatment.</p>
    Formula:C26H27N7O3S
    Purity:99.89%
    Color and Shape:Solid
    Molecular weight:517.6

    Ref: TM-T35529