CymitQuimica logo
CDK

CDK

CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.

Found 500 products of "CDK"

Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • AMG 925
    Targetmol
    + Info

    AMG 925

    CAS:
    <p>AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.</p>
    Formula:C26H29N7O2
    Purity:99.75%
    Color and Shape:Solid
    Molecular weight:471.55

    Ref: TM-T6756

  • CID44216842
    Targetmol
    + Info

    CID44216842

    CAS:
    <p>CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.</p>
    Formula:C22H20BrN3O3S
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:486.38

    Ref: TM-T8930

  • CVT-313
    Targetmol
    + Info

    CVT-313

    CAS:
    <p>CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.</p>
    Formula:C20H28N6O3
    Purity:97.46% - 97.97%
    Color and Shape:Solid
    Molecular weight:400.47

    Ref: TM-T3195

  • GSK 3 Inhibitor IX
    Targetmol
    + Info

    GSK 3 Inhibitor IX

    CAS:
    <p>GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.</p>
    Formula:C16H10BrN3O2
    Purity:98% - 99.72%
    Color and Shape:Solid
    Molecular weight:356.17

    Ref: TM-T1917

  • Purvalanol B
    Targetmol
    + Info

    Purvalanol B

    CAS:
    <p>Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)</p>
    Formula:C20H25ClN6O3
    Purity:98.95%
    Color and Shape:Solid
    Molecular weight:432.9

    Ref: TM-T7167

  • Palbociclib monohydrochloride
    Targetmol
    + Info

    Palbociclib monohydrochloride

    CAS:
    <p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>
    Formula:C24H29N7O2·HCl
    Purity:99.73% - >99.99%
    Color and Shape:Solid
    Molecular weight:483.99

    Ref: TM-T6239

  • Toyocamycin
    Targetmol
    + Info

    Toyocamycin

    CAS:
    <p>Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (</p>
    Formula:C12H13N5O4
    Purity:98.1% - 98.17%
    Color and Shape:Solid
    Molecular weight:291.26

    Ref: TM-T17143

  • Wogonin
    Targetmol
    + Info

    Wogonin

    CAS:
    <p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>
    Formula:C16H12O5
    Purity:98% - 99.8%
    Color and Shape:Yellow Crystal
    Molecular weight:284.26

    Ref: TM-T2933

  • Palbociclib Isethionate
    Targetmol
    + Info

    Palbociclib Isethionate

    CAS:
    <p>Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。</p>
    Formula:C24H29N7O2·C2H6O4S
    Purity:99.01% - 99.27%
    Color and Shape:Solid
    Molecular weight:573.66

    Ref: TM-T6240

  • SU9516
    Targetmol
    + Info

    SU9516

    CAS:
    <p>SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.</p>
    Formula:C13H11N3O2
    Purity:99.34% - 99.87%
    Color and Shape:Solid
    Molecular weight:241.25

    Ref: TM-T6167

  • BI-1347
    Targetmol
    + Info

    BI-1347

    CAS:
    <p>BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.</p>
    Formula:C22H20N4O
    Purity:96.7% - 99.63%
    Color and Shape:Solid
    Molecular weight:356.42

    Ref: TM-T5405

  • SRI-29329
    Targetmol
    + Info

    SRI-29329

    CAS:
    <p>SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).</p>
    Formula:C20H26ClN7
    Purity:99.18%
    Color and Shape:Solid
    Molecular weight:399.92

    Ref: TM-T8801

  • NSC23005
    Targetmol
    + Info

    NSC23005

    CAS:
    <p>NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).</p>
    Formula:C13H17NO4S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:283.34

    Ref: TM-T3590

  • AT7519
    Targetmol
    + Info

    AT7519

    CAS:
    <p>AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.</p>
    Formula:C16H17Cl2N5O2
    Purity:98.88% - 99.65%
    Color and Shape:Solid
    Molecular weight:382.24

    Ref: TM-T6205

  • (E/Z)-TG003
    Targetmol
    + Info

    (E/Z)-TG003

    CAS:
    <p>(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.</p>
    Formula:C13H15NO2S
    Purity:98% - 99.04%
    Color and Shape:Solid
    Molecular weight:249.33

    Ref: TM-T1901

  • TP-353
    Targetmol
    + Info

    TP-353

    CAS:
    <p>TP-353 (EOS-61973) is a CDK7 inhibitor.</p>
    Formula:C35H30FNO3
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:531.62

    Ref: TM-T22440

  • Trilaciclib
    Targetmol
    + Info

    Trilaciclib

    CAS:
    <p>Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.</p>
    Formula:C24H30N8O
    Purity:99.624%
    Color and Shape:Solid
    Molecular weight:446.55

    Ref: TM-T13202L

  • AZ5576
    Targetmol
    + Info

    AZ5576

    CAS:
    <p>AZ5576 is a potent and highly selective CDK9 inhibitor. AZ5576 can be used for the research of Hematological Malignancy [1].</p>
    Formula:C21H24FN3O3
    Purity:99.88%
    Color and Shape:Soild
    Molecular weight:385.43

    Ref: TM-T60152

  • CDK12-IN-5
    Targetmol
    + Info

    CDK12-IN-5

    CAS:
    <p>CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.</p>
    Formula:C18H15F5N8O
    Purity:99.37%
    Color and Shape:Solid
    Molecular weight:454.36

    Ref: TM-T40290

  • LSN2839567
    Targetmol
    + Info

    LSN2839567

    CAS:
    <p>LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.</p>
    Formula:C25H28F2N8
    Purity:99.14%
    Color and Shape:Solid
    Molecular weight:478.54

    Ref: TM-T10220

  • (R)-(+)-O-Demethylbuchenavianine
    Targetmol
    + Info

    (R)-(+)-O-Demethylbuchenavianine

    CAS:
    <p>(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, &gt;10 μM, &gt;10 μM, and &gt;10 μM, respectively.</p>
    Formula:C21H21NO4
    Color and Shape:Solid
    Molecular weight:351.40

    Ref: TM-T88435

  • Riviciclib hydrochloride
    Targetmol
    + Info

    Riviciclib hydrochloride

    CAS:
    <p>Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Phase 2/3.</p>
    Formula:C21H20ClNO5·HCl
    Purity:99.51%
    Color and Shape:Solid
    Molecular weight:438.3

    Ref: TM-T6924

  • XL413
    Targetmol
    + Info

    XL413

    CAS:
    <p>XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.</p>
    Formula:C14H12ClN3O2
    Purity:98.40% - >99.99%
    Color and Shape:Solid
    Molecular weight:289.72

    Ref: TM-T3352

  • MFH290
    Targetmol
    + Info

    MFH290

    CAS:
    <p>MFH290 is a selective CDK12/13 inhibitor, covalently bonding with CDK12 Cys-1039, blocks Pol II CTD phosphorylation, and enhances olaparib's efficacy.</p>
    Formula:C26H31N5O3S2
    Color and Shape:Solid
    Molecular weight:525.69

    Ref: TM-T69931

  • CDK2-IN-13
    Targetmol
    + Info

    CDK2-IN-13

    CAS:
    <p>CDK2-IN-13: Potent CDK2 inhibitor, arrests cell cycle, induces apoptosis, IC50=12 µM, used in cancer research.</p>
    Formula:C13H12ClN5
    Color and Shape:Soild
    Molecular weight:273.72

    Ref: TM-T60154

  • CDK8-IN-4
    Targetmol
    + Info

    CDK8-IN-4

    CAS:
    <p>CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).</p>
    Formula:C20H18N4O
    Color and Shape:Solid
    Molecular weight:330.38

    Ref: TM-T17305

  • CDK12-IN-3
    Targetmol
    + Info

    CDK12-IN-3

    CAS:
    <p>CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.</p>
    Formula:C23H28F2N8O
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:470.52

    Ref: TM-T14990

  • Cdc7-IN-5
    Targetmol
    + Info

    Cdc7-IN-5

    CAS:
    <p>Cdc7-IN-5: potent Cdc7 serine-threonine kinase inhibitor, critical for starting DNA replication.</p>
    Formula:C25H23N3O5
    Purity:97.15%
    Color and Shape:Solid
    Molecular weight:445.47

    Ref: TM-T10727

  • Cdc7-IN-9
    Targetmol
    + Info

    Cdc7-IN-9

    CAS:
    <p>Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].</p>
    Formula:C15H17N5OS
    Color and Shape:Solid
    Molecular weight:315.39

    Ref: TM-T60815

  • SNX2-1-108
    Targetmol
    + Info

    SNX2-1-108

    CAS:
    <p>SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.</p>
    Formula:C21H16N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.38

    Ref: TM-T24811

  • Metralindole HCl
    Targetmol
    + Info

    Metralindole HCl

    CAS:
    <p>Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.</p>
    Formula:C15H18ClN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:291.78

    Ref: TM-T28030

  • CDK7-IN-15
    Targetmol
    + Info

    CDK7-IN-15

    CAS:
    <p>CDK7-IN-15, a pyrimidine-based potent CDK7 inhibitor, shows promise for various cancers with defective transcription.</p>
    Formula:C21H24F4N6OS
    Color and Shape:Solid
    Molecular weight:484.51

    Ref: TM-T63217

  • BAY-958
    Targetmol
    + Info

    BAY-958

    CAS:
    <p>BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.</p>
    Formula:C17H16FN5O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:389.4

    Ref: TM-T23775

  • EGFR/CDK2-IN-1
    Targetmol
    + Info

    EGFR/CDK2-IN-1

    CAS:
    <p>EGFR/CDK2-IN-1, an inhibitor of both EGFR and CDK2, demonstrates effective cytotoxicity towards MCF7 and HepG2 cells, suggesting its potential application in</p>
    Formula:C19H12BrClO2
    Color and Shape:Solid
    Molecular weight:387.65

    Ref: TM-T72844

  • CDK7-IN-10
    Targetmol
    + Info

    CDK7-IN-10

    CAS:
    <p>CDK7-IN-10: CDK7 inhibitor, IC50&lt;100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)</p>
    Formula:C29H35N7O3
    Color and Shape:Solid
    Molecular weight:529.63

    Ref: TM-T63724

  • CDK7-IN-16
    Targetmol
    + Info

    CDK7-IN-16

    CAS:
    <p>CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.</p>
    Formula:C19H21F3N6O2S
    Color and Shape:Solid
    Molecular weight:454.47

    Ref: TM-T62791

  • Ipivivint
    Targetmol
    + Info

    Ipivivint

    CAS:
    <p>Ipivivint: orally active, potent CLK inhibitor; hinders CLK1, CLK2, &amp; CLK3; curbs Wnt signaling &amp; SRSF phosphorylation for cancer research.</p>
    Formula:C26H21FN8
    Color and Shape:Solid
    Molecular weight:464.5

    Ref: TM-T36684

  • NSC 693868
    Targetmol
    + Info

    NSC 693868

    CAS:
    <p>CDKs and GSK-3 inhibitor</p>
    Formula:C9H7N5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:185.19

    Ref: TM-T23093

  • Atuveciclib S-Enantiomer
    Targetmol
    + Info

    Atuveciclib S-Enantiomer

    CAS:
    <p>Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.</p>
    Formula:C18H18FN5O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.43

    Ref: TM-T10465

  • CDK8-IN-6
    Targetmol
    + Info

    CDK8-IN-6

    CAS:
    <p>CDK8-IN-6 (compound 9) is a potent inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 13 nM), CDK8-IN-6 showed potential research value in AML cancers.</p>
    Formula:C26H37ClN2
    Color and Shape:Solid
    Molecular weight:413.04

    Ref: TM-T62112

  • CDK4/6-IN-14
    Targetmol
    + Info

    CDK4/6-IN-14

    CAS:
    <p>CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, &gt;60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.</p>
    Formula:C24H27ClFN7O
    Color and Shape:Solid
    Molecular weight:483.97

    Ref: TM-T72951

  • KH-CB19
    Targetmol
    + Info

    KH-CB19

    CAS:
    <p>KH-CB19 is an effective and highly specific inhibitor of the CDC2-like kinase isoforms 1 and 4 (CLK1/CLK4).</p>
    Formula:C15H13Cl2N3O2
    Color and Shape:Solid
    Molecular weight:338.19

    Ref: TM-T15657

  • Cdc7-IN-14
    Targetmol
    + Info

    Cdc7-IN-14

    CAS:
    <p>Cdc7-IN-14 (compound 82) is a potent CDC7 inhibitor with an IC50 &lt; 1 nM, promising for cancer research.</p>
    Formula:C18H20N4O2S
    Color and Shape:Solid
    Molecular weight:356.44

    Ref: TM-T61289

  • CDK9-IN-15
    Targetmol
    + Info

    CDK9-IN-15

    CAS:
    <p>CDK9-IN-15: potent CDK9 inhibitor, blocks P-TEFb phosphorylation, inhibits transcription, reduces mRNA, induces tumor cell apoptosis.</p>
    Formula:C16H11N3OS
    Purity:97.24%
    Color and Shape:Solid
    Molecular weight:293.34

    Ref: TM-T60619

  • CDK-IN-10
    Targetmol
    + Info

    CDK-IN-10

    CAS:
    <p>CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.</p>
    Formula:C18H18N4O2
    Purity:97.07%
    Color and Shape:Solid
    Molecular weight:322.36

    Ref: TM-T60869

  • CLK1-IN-2
    Targetmol
    + Info

    CLK1-IN-2

    <p>CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.</p>
    Formula:C16H12Cl2N2O2S
    Color and Shape:Solid
    Molecular weight:367.25

    Ref: TM-T73321

  • XIE18-6
    Targetmol
    + Info

    XIE18-6

    CAS:
    <p>XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.</p>
    Formula:C18H15NO6S
    Purity:99.712%
    Color and Shape:Solid
    Molecular weight:373.38

    Ref: TM-T29166

  • NSC 625987
    Targetmol
    + Info

    NSC 625987

    CAS:
    <p>Cyclin-dependent kinase (cdk) 4 inhibitor</p>
    Formula:C15H13NO2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:271.33

    Ref: TM-T23092

  • ARN22089
    Targetmol
    + Info

    ARN22089

    CAS:
    <p>ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.</p>
    Formula:C23H27N5
    Purity:98.37%
    Color and Shape:Solid
    Molecular weight:373.49

    Ref: TM-T85727

  • CDK8/19-IN-51
    Targetmol
    + Info

    CDK8/19-IN-51

    CAS:
    <p>CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.</p>
    Formula:C23H22N6O2
    Purity:98.65% - 99.62%
    Color and Shape:Soild
    Molecular weight:414.46

    Ref: TM-T22633