CDK

CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.

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Brand	Product data	Purity	Price range	Estimated delivery
	HS-243 REF: TM-T60012CAS: 848249-10-5	97.34%	52.00 €~800.00 €	Mon 28 Apr 25
	CDK4-IN-1 REF: TM-T2082CAS: 1256963-02-6	98%	To inquire	Mon 28 Apr 25
	PF07104091 REF: TM-T9712CAS: 2460249-19-6	98.61%	354.00 €~3,258.00 €	Mon 28 Apr 25
	CDK2 degrader 3 REF: TM-T201636CAS: 2862772-71-0	- - -	To inquire	Mon 28 Apr 25
	bio-THZ1 REF: TM-T10546CAS: 1604811-14-4	98%	2,183.00 €~4,474.00 €	Mon 28 Apr 25
	H1k REF: TM-T72057	98.38%	185.00 €~1,872.00 €	Mon 28 Apr 25
	CDK9-IN-26 REF: TM-T79631	98%	To inquire	Mon 28 Apr 25
	PROTAC CDK9/CycT1 Degrader-2 REF: TM-T79904	98%	To inquire	Mon 28 Apr 25
	SHR5428 REF: TM-T79604	98%	To inquire	Mon 28 Apr 25
	CDK2-IN-20 REF: TM-T82759	98%	To inquire	Mon 28 Apr 25
	Avotaciclib hydrochloride REF: TM-T78137	98%	To inquire	Mon 28 Apr 25
	CDK2/Bcl2-IN-1 REF: TM-T78813	98%	To inquire	Mon 28 Apr 25
	CDK9-IN-28 REF: TM-T79704	98%	To inquire	Mon 28 Apr 25
	CAF-382 REF: TM-T79606	98%	To inquire	Mon 28 Apr 25
	CDK9-Cyclin T1 PPI-IN-1 REF: TM-T82758	98%	To inquire	Mon 28 Apr 25
	CDK2-IN-19 REF: TM-T79648	98%	To inquire	Mon 28 Apr 25
	CDK9-IN-24 REF: TM-T79354	98%	To inquire	Mon 28 Apr 25
	ZNL-05-044 REF: TM-T79640	98%	To inquire	Mon 28 Apr 25
	CDK9-IN-27 REF: TM-T79367	98%	To inquire	Mon 28 Apr 25
	CP-07 REF: TM-T78837	98%	To inquire	Mon 28 Apr 25

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HS-243

CAS:848249-10-5

HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. …

Formula:

C₁₇H₁₆N₄O₃

Purity:

97.34%

Color and Shape:

Liquid

Molecular weight:

324.33

Ref: TM-T60012

1mg		52.00 €
5mg		111.00 €
10mg		187.00 €
25mg		378.00 €
50mg		560.00 €
100mg		800.00 €

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK4-IN-1

CAS:1256963-02-6

CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 …

Formula:

C₂₂H₂₉ClN₈

Purity:

98%

Color and Shape:

Solid

Molecular weight:

440.97

Ref: TM-T2082

25mg 1,444.00 €

Estimated delivery in United States, on Monday 28 Apr 2025

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PF07104091

CAS:2460249-19-6

PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor …

Formula:

C₁₉H₂₈N₆O₄

Purity:

98.61%

Color and Shape:

Solid

Molecular weight:

404.46

Ref: TM-T9712

1mg		354.00 €
2mg		518.00 €
5mg		823.00 €
10mg		1,206.00 €
25mg		1,795.00 €
50mg		2,422.00 €
100mg		3,258.00 €
1mL*10mM (DMSO)		914.00 €

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK2 degrader 3

CDK2 degrader 3

CAS:2862772-71-0

CDK2 degrader3 selectively degrades CDK2 and exhibits antitumor activity.

Formula:

C₄₄H₅₃ClN₁₀O₆S

Color and Shape:

Liquid

Molecular weight:

885.47

Ref: TM-T201636

10mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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bio-THZ1

CAS:1604811-14-4

bio-THZ1 is a biotinylated version of THZ1. THZ1 is a selective and irreversibly covalent CDK7 …

Formula:

C₅₂H₆₅ClN₁₂O₈S

Purity:

98%

Color and Shape:

Solid

Molecular weight:

1053.67

Ref: TM-T10546

10mg		2,183.00 €
25mg		4,474.00 €

Estimated delivery in United States, on Monday 28 Apr 2025

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H1k

H1k is an eudistomin Y fluorescent derivative and lysosome-targeted antiproliferative agent that downregulates the expression …

Formula:

C₂₇H₂₂N₂O

Purity:

98.38%

Color and Shape:

Soild

Molecular weight:

390.48

Ref: TM-T72057

1mg		185.00 €
5mg		459.00 €
10mg		657.00 €
25mg		1,026.00 €
50mg		1,415.00 €
100mg		1,872.00 €

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK9-IN-26

CDK9-IN-26, also known as compound 1, is a potent inhibitor of Cyclin-Dependent Kinase 9 (CDK9) …

Formula:

C₁₇H₁₄N₄O₂

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

306.32

Ref: TM-T79631

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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PROTAC CDK9/CycT1 Degrader-2

PROTAC CDK9/CycT1 Degrader-2 inhibits CDK9 with an IC50 of 45 nM [1].

Formula:

C₃₀H₃₆N₄O₆S₂

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

612.76

Ref: TM-T79904

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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SHR5428

SHR5428 is an orally active, selective, noncovalent inhibitor of CDK7, displaying potent enzymatic inhibition (IC50 …

Purity:

98%

Color and Shape:

Odour Solid

Ref: TM-T79604

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK2-IN-20

CDK2-IN-20 (compound 3b), a CDK2 inhibitor, exhibits cytotoxic effects on tumor cells with an IC50 …

Purity:

98%

Color and Shape:

Odour Solid

Ref: TM-T82759

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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Avotaciclib hydrochloride

Avotaciclib hydrochloride, a CDK1 inhibitor, is the hydrochloride salt of Avotaciclib and exhibits potential therapeutic …

Formula:

C₁₃H₁₂ClN₇O

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

317.73

Ref: TM-T78137

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK2/Bcl2-IN-1

CDK2/Bcl2-IN-1 (compound 1) is a saponin-based inhibitor of CDK-2 (IC50=117.6 nM) that exhibits potent cytotoxic …

Formula:

C₃₅H₅₆O₁₀S

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

668.88

Ref: TM-T78813

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK9-IN-28

PROTAC CDK9/CycT1 Degrader-1 (compounds 10), a potent CDK9 inhibitor, serves as a target protein ligand …

Formula:

C₃₂H₄₀N₄O₆S₂

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

640.81

Ref: TM-T79704

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CAF-382

CAF-382 (compound B1), an analog of SNS-032, functions as a CDKL5 and pan-CDK inhibitor, exhibiting …

Formula:

C₁₆H₂₂N₄O₂S₂

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

366.5

Ref: TM-T79606

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK9-Cyclin T1 PPI-IN-1

CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction …

Purity:

98%

Color and Shape:

Odour Solid

Ref: TM-T82758

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK2-IN-19

CDK2-IN-19 (Compound 32) is a selective, orally active inhibitor of CDK2 (K i: 0.18 nM) …

Formula:

C₂₀H₂₁FN₆O₄S

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

460.48

Ref: TM-T79648

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK9-IN-24

CDK9-IN-24 (compound 21a) is a potent and selective inhibitor of CDK9 that exhibits a pronounced …

Formula:

C₂₇H₃₁N₃O₄

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

461.55

Ref: TM-T79354

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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ZNL-05-044

ZNL-05-044, a CDK11 inhibitor, exhibits IC50 values of 0.23 μM for CDK11A and 0.27 μM …

Formula:

C₂₁H₂₂Cl₂N₆OS

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

477.41

Ref: TM-T79640

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CDK9-IN-27

CDK9-IN-27 (Compound 6a), a CDK9 inhibitor with an IC50 of 0.424 μM, induces apoptosis and …

Formula:

C₂₃H₁₈ClN₅O₃

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

447.87

Ref: TM-T79367

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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CP-07

CP-07 is a selective and effective PROTAC CDK9 degrader (DC50: 43 nM), demonstrating inhibition of …

Formula:

C₄₅H₄₈N₆O₈

Purity:

98%

Color and Shape:

Liquid

Molecular weight:

800.9

Ref: TM-T78837

5mg		To inquire
50mg		To inquire

Estimated delivery in United States, on Monday 28 Apr 2025

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