CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
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Voruciclib
CAS:1000023-04-0
Voruciclib: oral, selective CDK inhibitor (Ki: 0.626-9.1 nM), reduces MCL-1, targets CDK9 in diffuse large …
Formula:
C22H19ClF3NO5
Purity:
99.89%
Color and Shape:
Solid
Molecular weight:
469.84
Ref: TM-T10096L
| 1mg | 143.00 € | ||
| 5mg | 269.00 € | ||
| 10mg | 423.00 € | ||
| 25mg | 827.00 € | ||
| 1mL*10mM (DMSO) | 280.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Longdaysin
CAS:1353867-91-0
Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit …
Formula:
C16H16F3N5
Purity:
99.97%
Color and Shape:
Solid
Molecular weight:
335.33
Ref: TM-T5358
| 5mg | 50.00 € | ||
| 10mg | 74.00 € | ||
| 25mg | 135.00 € | ||
| 50mg | 208.00 € | ||
| 100mg | 315.00 € | ||
| 200mg | 451.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
InhA-IN-2
CAS:2428737-43-1
N-[3-(Aminomethyl)phenyl]-5-chloro-3-methyl-benzo[b]thiophene-2-sulfonamide inhibits InhA without KatG activation.
Formula:
C16H15ClN2O2S2
Purity:
98.4%
Color and Shape:
Solid
Molecular weight:
366.89
Ref: TM-T9734
| 1mg | 94.00 € | ||
| 5mg | 185.00 € | ||
| 10mg | 273.00 € | ||
| 25mg | 436.00 € | ||
| 50mg | 621.00 € | ||
| 100mg | 835.00 € | ||
| 200mg | 1,089.00 € | ||
| 1mL*10mM (DMSO) | 191.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
TC11
CAS:100823-03-8
TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of …
Formula:
C20H22N2O2
Purity:
97.86%
Color and Shape:
Solid
Molecular weight:
322.4
Ref: TM-T9083
| 2mg | 40.00 € | ||
| 5mg | 60.00 € | ||
| 10mg | 95.00 € | ||
| 25mg | 186.00 € | ||
| 50mg | 308.00 € | ||
| 100mg | 466.00 € | ||
| 1mL*10mM (DMSO) | 46.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY2857785
CAS:1619903-54-6
LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 …
Formula:
C26H36N6O
Purity:
99.68%
Color and Shape:
Solid Powder
Molecular weight:
448.6
Ref: TM-TQ0060
| 1mg | 53.00 € | ||
| 2mg | 74.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 173.00 € | ||
| 25mg | 351.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 905.00 € | ||
| 1mL*10mM (DMSO) | 123.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
BS194
CAS:1092443-55-4
BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.
Formula:
C20H27N5O3
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
385.46
Ref: TM-T7698
| 1mg | 79.00 € | ||
| 5mg | 172.00 € | ||
| 10mg | 258.00 € | ||
| 25mg | 439.00 € | ||
| 50mg | 629.00 € | ||
| 100mg | 879.00 € | ||
| 1mL*10mM (DMSO) | 239.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Palbociclib
CAS:571190-30-2
Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor …
Formula:
C24H29N7O2
Purity:
98% - 99.9%
Color and Shape:
Solid
Molecular weight:
447.53
Ref: TM-T1785
| 5mg | 52.00 € | ||
| 10mg | 73.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
CDK4/6-IN-6
CAS:2380321-51-5
CDK4/6-IN-6 is a potent CDK4/CDK6 inhibitor with Ki of 0.6 nM and 13.9 nM for …
Formula:
C22H27ClFN5O3
Purity:
95.63%
Color and Shape:
Solid
Molecular weight:
463.93
Ref: TM-T39957
| 1mg | 111.00 € | ||
| 5mg | 230.00 € | ||
| 10mg | 369.00 € | ||
| 25mg | 620.00 € | ||
| 50mg | 878.00 € | ||
| 100mg | 1,194.00 € | ||
| 1mL*10mM (DMSO) | 271.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
OTS964 hydrochloride
CAS:1338545-07-5
OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.
Formula:
C23H24N2O2S·HCl
Purity:
96.5% - 98.02%
Color and Shape:
Solid
Molecular weight:
428.97
Ref: TM-T4135
| 1mg | 45.00 € | ||
| 2mg | 59.00 € | ||
| 5mg | 92.00 € | ||
| 10mg | 122.00 € | ||
| 25mg | 193.00 € | ||
| 50mg | 343.00 € | ||
| 100mg | 510.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NU2058
CAS:161058-83-9
NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.
Formula:
C12H17N5O
Purity:
98.43% - 99.95%
Color and Shape:
Solid
Molecular weight:
247.3
Ref: TM-T3186
| 5mg | 34.00 € | ||
| 10mg | 51.00 € | ||
| 25mg | 87.00 € | ||
| 50mg | 121.00 € | ||
| 100mg | 181.00 € | ||
| 200mg | 268.00 € | ||
| 1mL*10mM (DMSO) | 45.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Amsilarotene
CAS:125973-56-0
Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate …
Formula:
C20H27NO3Si2
Purity:
99.27%
Color and Shape:
Solid
Molecular weight:
385.6
Ref: TM-T21314
| 1mg | 42.00 € | ||
| 2mg | 55.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 136.00 € | ||
| 25mg | 263.00 € | ||
| 50mg | 379.00 € | ||
| 100mg | 540.00 € | ||
| 200mg | 730.00 € | ||
| 1mL*10mM (DMSO) | 92.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Aminopurvalanol A
CAS:220792-57-4
Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently …
Formula:
C19H26ClN7O
Purity:
99.64%
Color and Shape:
Solid
Molecular weight:
403.91
Ref: TM-T22260
| 2mg | 41.00 € | ||
| 5mg | 62.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 177.00 € | ||
| 50mg | 274.00 € | ||
| 100mg | 398.00 € | ||
| 200mg | 565.00 € | ||
| 1mL*10mM (DMSO) | 63.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Indirubin-3′-oxime
CAS:667463-82-3
Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role …
Formula:
C16H11N3O2
Purity:
98.34%
Color and Shape:
Solid
Molecular weight:
277.28
Ref: TM-T9138
| 1mg | 46.00 € | ||
| 2mg | 40.00 € | ||
| 5mg | 96.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 275.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 625.00 € | ||
| 200mg | 520.00 € | ||
| 1mL*10mM (DMSO) | 121.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ZCL278
CAS:587841-73-4
ZCL278 is a selective Cdc42 GTPase inhibitor.
Formula:
C21H19BrClN5O4S2
Purity:
96.29% - 99.72%
Color and Shape:
Solid
Molecular weight:
584.89
Ref: TM-T1855
| 5mg | 51.00 € | ||
| 10mg | 79.00 € | ||
| 25mg | 136.00 € | ||
| 50mg | 221.00 € | ||
| 100mg | 311.00 € | ||
| 200mg | 497.00 € | ||
| 500mg | 791.00 € | ||
| 1mL*10mM (DMSO) | 79.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
SNS-032
CAS:345627-80-7
SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over …
Formula:
C17H24N4O2S2
Purity:
98.27% - 99.44%
Color and Shape:
Solid
Molecular weight:
380.53
Ref: TM-T6049
| 5mg | 51.00 € | ||
| 10mg | 66.00 € | ||
| 25mg | 95.00 € | ||
| 50mg | 128.00 € | ||
| 100mg | 209.00 € | ||
| 200mg | 310.00 € | ||
| 500mg | 520.00 € | ||
| 1mL*10mM (DMSO) | 53.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
NVP-LCQ195
CAS:902156-99-4
NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 …
Formula:
C17H19Cl2N5O4S
Purity:
100% - 99.36%
Color and Shape:
Solid
Molecular weight:
460.33
Ref: TM-TQ0068
| 1mg | 46.00 € | ||
| 5mg | 93.00 € | ||
| 10mg | 141.00 € | ||
| 25mg | 259.00 € | ||
| 50mg | 381.00 € | ||
| 100mg | 543.00 € | ||
| 200mg | 717.00 € | ||
| 1mL*10mM (DMSO) | 95.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
LY3177833
CAS:1627696-51-8
LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)
Formula:
C16H12FN5O
Purity:
99.87%
Color and Shape:
Solid
Molecular weight:
309.3
Ref: TM-T7810
| 1mg | 40.00 € | ||
| 5mg | 84.00 € | ||
| 10mg | 114.00 € | ||
| 25mg | 221.00 € | ||
| 50mg | 331.00 € | ||
| 100mg | 496.00 € | ||
| 200mg | 706.00 € | ||
| 1mL*10mM (DMSO) | 91.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Abemaciclib methanesulfonate
CAS:1231930-82-7
Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).
Formula:
C27H32F2N8·CH4O3S
Purity:
98.69% - 99.44%
Color and Shape:
Solid
Molecular weight:
602.7
Ref: TM-T3111
| 2mg | 35.00 € | ||
| 5mg | 54.00 € | ||
| 10mg | 78.00 € | ||
| 25mg | 93.00 € | ||
| 50mg | 95.00 € | ||
| 100mg | 122.00 € | ||
| 200mg | 151.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Cucurbitacin E
CAS:18444-66-1
Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain …
Formula:
C32H44O8
Purity:
98.88% - 99.19%
Color and Shape:
Solid
Molecular weight:
556.69
Ref: TM-T5S1467
| 1mg | 58.00 € | ||
| 5mg | 113.00 € | ||
| 10mg | 175.00 € | ||
| 25mg | 294.00 € | ||
| 50mg | 436.00 € | ||
| 100mg | 631.00 € | ||
| 1mL*10mM (DMSO) | 140.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
KB-0742 dihydrochloride
CAS:2416874-75-2
KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.
Formula:
C16H27Cl2N5
Purity:
99.32%
Color and Shape:
Solid
Molecular weight:
360.33
Ref: TM-T9446
| 1mg | 94.00 € | ||
| 2mg | 141.00 € | ||
| 5mg | 231.00 € | ||
| 10mg | 371.00 € | ||
| 25mg | 618.00 € | ||
| 50mg | 878.00 € | ||
| 100mg | 1,189.00 € | ||
| 1mL*10mM (DMSO) | 248.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
