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Microtubule Associated

Microtubule Associated

Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.

Found 261 products of "Microtubule Associated"

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  • KIF18A-IN-4

    CAS:
    <p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>
    Formula:C22H27N3O3S
    Color and Shape:Solid
    Molecular weight:413.53
  • Antitumor agent-68

    CAS:
    <p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>
    Formula:C17H11NO2
    Color and Shape:Solid
    Molecular weight:261.27
  • Antitumor agent-71

    CAS:
    <p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>
    Formula:C26H31N5O4S
    Color and Shape:Solid
    Molecular weight:509.62
  • IDT

    CAS:
    <p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>
    Formula:C8H5NS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:179.26
  • DHNQ

    CAS:
    <p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>
    Formula:C18H14N2O
    Color and Shape:Solid
    Molecular weight:274.32
  • D011-2120

    CAS:
    <p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>
    Formula:C17H15NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.31
  • DAT1

    CAS:
    <p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>
    Formula:C17H15N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:325.38
  • Acodazole

    CAS:
    <p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>
    Formula:C20H19N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:345.4
  • Acodazole hydrochloride

    CAS:
    <p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>
    Formula:C20H20ClN5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:381.86
  • LDN-193665

    CAS:
    <p>LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.</p>
    Formula:C15H11FN4OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:314.34
  • GF 15

    CAS:
    <p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>
    Formula:C23H21ClO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:428.86
  • TOK-8801

    CAS:
    <p>TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.</p>
    Formula:C17H21N3OS
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:315.43
  • Mivobulin

    CAS:
    <p>Mivobulin is an inhibitor of tubulin .</p>
    Formula:C17H19N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:325.37
  • S-methyl DM1

    CAS:
    <p>S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.</p>
    Formula:C36H50ClN3O10S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:752.31
  • Cevipabulin

    CAS:
    <p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>
    Formula:C18H18ClF5N6O
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:464.82
  • Tau-aggregation and neuroinflammation-IN-1

    CAS:
    <p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>
    Formula:C25H20N2O7
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:460.44
  • CCB02

    CAS:
    <p>CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.</p>
    Formula:C14H9N3O
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:235.24
  • S516

    CAS:
    <p>S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.</p>
    Formula:C21H19N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:437.47
  • Tubulin inhibitor 8

    CAS:
    <p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>
    Formula:C21H14N2O3
    Purity:98.51% - 99.87%
    Color and Shape:Solid
    Molecular weight:342.35
  • TCS 2210

    CAS:
    <p>TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.</p>
    Formula:C18H17N3O3
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:323.35