Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 274 products of "Microtubule Associated"
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Tubulin polymerization-IN-19
CAS:Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.Formula:C25H25NO5Color and Shape:SolidMolecular weight:419.47DJ101
CAS:DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.Formula:C23H20N4O3Purity:98%Color and Shape:SolidMolecular weight:400.43Tubulin polymerization-IN-27
CAS:Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.Formula:C22H20N2O2Color and Shape:SolidMolecular weight:344.41Aha1/Hsp90-IN-1
CAS:Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.Formula:C22H17F3N4O2Color and Shape:SolidMolecular weight:426.39MG-2119
CAS:MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.Formula:C27H29N5O4Color and Shape:SolidMolecular weight:487.55isoCA-4
CAS:isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].Formula:C18H20O5Color and Shape:SolidMolecular weight:316.35Tubulin polymerization-IN-29
CAS:Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.Formula:C25H20FNO6Color and Shape:SolidMolecular weight:449.43BNC105P
CAS:BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.Formula:C20H21O10PColor and Shape:SolidMolecular weight:452.3485Microtubule inhibitor 4
CAS:Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).Formula:C25H23FN4O3Color and Shape:SolidMolecular weight:446.47Tubulin inhibitor 27
CAS:DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.Formula:C21H19NO4Color and Shape:SolidMolecular weight:349.38Tubulin polymerization-IN-21
CAS:Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.Formula:C30H29NO7Color and Shape:SolidMolecular weight:515.55Tubulin polymerization-IN-10
CAS:Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.Formula:C18H21NO6SColor and Shape:SolidMolecular weight:379.43Neuroinflammatory-IN-3
CAS:Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.Formula:C19H19ClO3Color and Shape:SolidMolecular weight:330.81Tubulin polymerization-IN-36
CAS:Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.Formula:C18H18N2O3Color and Shape:SolidMolecular weight:310.35Tubulin polymerization-IN-16
CAS:Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.Formula:C24H27N5O5Color and Shape:SolidMolecular weight:465.5O-GlcNAcase-IN-4
CAS:O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.Formula:C16H22FN5O3SColor and Shape:SolidMolecular weight:383.44Tubulin polymerization-IN-18
CAS:Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.Formula:C25H25NO6Color and Shape:SolidMolecular weight:435.47Synstab A
CAS:Synstab A is a microtubule stabilizer.Formula:C15H13BrCl3N3O3SColor and Shape:SolidMolecular weight:501.61Microtubule inhibitor 7
CAS:Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.Formula:C25H19FN2O5Color and Shape:SolidMolecular weight:446.43(S)-Dolaphenine hydrochloride
CAS:(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.Formula:C11H13ClN2SPurity:98%Color and Shape:SolidMolecular weight:240.75
