Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 261 products of "Microtubule Associated"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
MMAD
CAS:<p>MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).</p>Formula:C41H66N6O6SPurity:99.25% - 99.91%Color and Shape:SolidMolecular weight:771.06MMAF
CAS:<p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>Formula:C39H65N5O8Purity:97.00% - 99.88%Color and Shape:SolidMolecular weight:731.96Estramustine
CAS:<p>Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.</p>Formula:C23H31Cl2NO3Purity:98.09%Color and Shape:SolidMolecular weight:440.4Albendazole sulfoxide
CAS:<p>Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.</p>Formula:C12H15N3O3SPurity:97.29%Color and Shape:White To Off-White PowderMolecular weight:281.33Suprafenacine
CAS:<p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>Formula:C16H18N4OPurity:99.91%Color and Shape:SolidMolecular weight:282.34Vindesine sulfate
CAS:<p>Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.</p>Formula:C43H57N5O11SPurity:97.51%Color and Shape:Amorphous SolidMolecular weight:852Spastazoline
CAS:<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Formula:C20H30N8Purity:99.23%Color and Shape:SolidMolecular weight:382.51Clanfenur
CAS:<p>Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.</p>Formula:C16H15ClFN3O2Purity:99.93%Color and Shape:SolidMolecular weight:335.764-Isopropoxybenzoic acid
CAS:<p>4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.</p>Formula:C10H12O3Purity:99.88%Color and Shape:White To Off-White PowderMolecular weight:180.2NQTrp
CAS:<p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>Formula:C21H16N2O4Purity:98.35%Color and Shape:SolidMolecular weight:360.364-Desacetylvinblastine hydrazide
CAS:<p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>Formula:C43H56N6O7Color and Shape:SolidMolecular weight:768.94Gosuranemab
CAS:<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Purity:95% - 95%Color and Shape:LiquidPosdinemab
CAS:<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Color and Shape:LiquidSemorinemab
CAS:<p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>Purity:95% - 95%Color and Shape:LiquidST-401
CAS:<p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>Formula:C24H20N2OColor and Shape:SolidMolecular weight:352.43Tubulin polymerization-IN-2
CAS:<p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>Formula:C17H12F2N2O2Color and Shape:SolidMolecular weight:314.29Auristatin F
CAS:<p>Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.</p>Formula:C40H67N5O8Purity:98.41% - 99.25%Color and Shape:SolidMolecular weight:745.99Sabeluzole
CAS:<p>Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.</p>Formula:C22H26FN3O2SPurity:98.51%Color and Shape:SolidMolecular weight:415.52AM-5308
CAS:<p>AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.</p>Formula:C26H35N5O5SPurity:98.06% - 99.58%Color and Shape:SolidMolecular weight:529.65Tau protein aggregation-IN-1
CAS:<p>Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders</p>Formula:C17H11BrN2O2Color and Shape:SolidMolecular weight:355.19OSIP-486823
CAS:<p>OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.</p>Formula:C29H28FNO4Purity:98.59%Color and Shape:SolidMolecular weight:473.54IQTub4P
CAS:<p>IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).</p>Formula:C19H18NNa2O8PColor and Shape:SolidMolecular weight:465.305Tubulin polymerization-IN-42
CAS:<p>Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].</p>Formula:C22H21NO5Color and Shape:SolidMolecular weight:379.41Alyssin
CAS:<p>Alyssin: sulforaphane analog, antioxidant; boosts Nrf2 and phase II enzymes in cancer cells; lowers PAH metabolism, reducing cancer risk in vitro.</p>Formula:C7H13NOS2Purity:98%Color and Shape:SolidMolecular weight:191.31Tubulozole
CAS:<p>Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.</p>Formula:C23H23Cl2N3O4SPurity:98%Color and Shape:SolidMolecular weight:508.42Sirt1/2-IN-1
CAS:<p>Sirt1/2-IN-1 inhibits SIRT1 (IC50: 1.81 μg/mL) and SIRT2 (2.10 μg/mL), less on SIRT3 (20.5 μg/mL), with anticancer properties.</p>Formula:C22H13ClN2OS2Color and Shape:SolidMolecular weight:420.93Amphethinile
CAS:<p>Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.</p>Formula:C15H11N3SPurity:98%Color and Shape:SolidMolecular weight:265.33Microtubule inhibitor 3
CAS:<p>Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.</p>Formula:C26H23FN4O3Color and Shape:SolidMolecular weight:458.48Microtubule inhibitor 1
CAS:<p>Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).</p>Formula:C21H19NO3Purity:98%Color and Shape:SolidMolecular weight:333.38Anticancer agent 48
CAS:<p>Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.</p>Formula:C26H25N3O4Color and Shape:SolidMolecular weight:443.49Tubulin polymerization-IN-39
<p>Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.</p>Formula:C21H21N5O5Color and Shape:SolidMolecular weight:423.42Tubulin inhibitor 28
CAS:<p>Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.</p>Formula:C12H8Br2S2Color and Shape:SolidMolecular weight:376.13Tubulin inhibitor 7
CAS:<p>Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (</p>Formula:C21H14N2O4Purity:98%Color and Shape:SolidMolecular weight:358.35MT-7
CAS:<p>MT-7 is a tubulin polymerization inhibitor.</p>Formula:C22H17N3O2Purity:98%Color and Shape:SolidMolecular weight:355.39Anticancer agent 49
CAS:<p>Anticancer agent 49, also 69, hinders cell growth and microtubule aggregation, with potential in solid and blood cancer research.</p>Formula:C26H25N3O4Color and Shape:SolidMolecular weight:443.49Tubulin polymerization-IN-19
CAS:<p>Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.</p>Formula:C25H25NO5Color and Shape:SolidMolecular weight:419.47DJ101
CAS:<p>DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.</p>Formula:C23H20N4O3Purity:98%Color and Shape:SolidMolecular weight:400.43Tubulin polymerization-IN-27
CAS:<p>Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.</p>Formula:C22H20N2O2Color and Shape:SolidMolecular weight:344.41Aha1/Hsp90-IN-1
CAS:<p>Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.</p>Formula:C22H17F3N4O2Color and Shape:SolidMolecular weight:426.39MG-2119
CAS:<p>MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.</p>Formula:C27H29N5O4Color and Shape:SolidMolecular weight:487.55isoCA-4
CAS:<p>isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].</p>Formula:C18H20O5Color and Shape:SolidMolecular weight:316.35Tubulin polymerization-IN-29
CAS:<p>Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.</p>Formula:C25H20FNO6Color and Shape:SolidMolecular weight:449.43BNC105P
CAS:<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Formula:C20H21O10PColor and Shape:SolidMolecular weight:452.3485Microtubule inhibitor 4
CAS:<p>Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).</p>Formula:C25H23FN4O3Color and Shape:SolidMolecular weight:446.47Tubulin inhibitor 27
CAS:<p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>Formula:C21H19NO4Color and Shape:SolidMolecular weight:349.38Tubulin polymerization-IN-21
CAS:<p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>Formula:C30H29NO7Color and Shape:SolidMolecular weight:515.55Tubulin polymerization-IN-10
CAS:<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Formula:C18H21NO6SColor and Shape:SolidMolecular weight:379.43Neuroinflammatory-IN-3
CAS:<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Formula:C19H19ClO3Color and Shape:SolidMolecular weight:330.81Tubulin polymerization-IN-36
CAS:<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Formula:C18H18N2O3Color and Shape:SolidMolecular weight:310.35Tubulin polymerization-IN-16
CAS:<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Formula:C24H27N5O5Color and Shape:SolidMolecular weight:465.5
