Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 274 products of "Microtubule Associated"
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Tubulin polymerization-IN-21
CAS:Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.Formula:C30H29NO7Color and Shape:SolidMolecular weight:515.55Tubulin polymerization-IN-10
CAS:Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.Formula:C18H21NO6SColor and Shape:SolidMolecular weight:379.43Neuroinflammatory-IN-3
CAS:Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.Formula:C19H19ClO3Color and Shape:SolidMolecular weight:330.81Tubulin polymerization-IN-36
CAS:Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.Formula:C18H18N2O3Color and Shape:SolidMolecular weight:310.35Tubulin polymerization-IN-16
CAS:Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.Formula:C24H27N5O5Color and Shape:SolidMolecular weight:465.5O-GlcNAcase-IN-4
CAS:O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.Formula:C16H22FN5O3SColor and Shape:SolidMolecular weight:383.44Tubulin polymerization-IN-18
CAS:Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.Formula:C25H25NO6Color and Shape:SolidMolecular weight:435.47Synstab A
CAS:Synstab A is a microtubule stabilizer.Formula:C15H13BrCl3N3O3SColor and Shape:SolidMolecular weight:501.61Microtubule inhibitor 7
CAS:Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.Formula:C25H19FN2O5Color and Shape:SolidMolecular weight:446.43(S)-Dolaphenine hydrochloride
CAS:(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.Formula:C11H13ClN2SPurity:98%Color and Shape:SolidMolecular weight:240.75Deox B 7,4
CAS:Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.Formula:C18H18O5Color and Shape:SolidMolecular weight:314.33Tubulin polymerization-IN-30
CAS:Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.Formula:C22H25N5O3Color and Shape:SolidMolecular weight:407.47Tubulin inhibitor 29
CAS:Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.Formula:C12H8F2O2S2Color and Shape:SolidMolecular weight:286.32Microtubule inhibitor 6
CAS:Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.Formula:C24H19FN2O5Color and Shape:SolidMolecular weight:434.42Tubulin inhibitor 31
Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.Formula:C22H19NO2Color and Shape:SolidMolecular weight:329.39Tubulin polymerization-IN-7
CAS:Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.Formula:C28H24N4O6SColor and Shape:SolidMolecular weight:544.58Anticancer agent 60
CAS:Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.Formula:C27H33N5O4SColor and Shape:SolidMolecular weight:523.65SB26019
CAS:SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.Formula:C24H20O4Color and Shape:SolidMolecular weight:372.41AMXI-5001
CAS:AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.Formula:C25H20FN5O3Color and Shape:SolidMolecular weight:457.46Tubulin inhibitor 20
CAS:Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].Formula:C19H18O4Color and Shape:SolidMolecular weight:310.34Tubulin inhibitor 26
CAS:Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.Formula:C17H19N3O3Color and Shape:SolidMolecular weight:313.35Microtubule inhibitor 5
CAS:Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.Formula:C22H15FN2O4Color and Shape:SolidMolecular weight:390.36Tubulin polymerization-IN-37
CAS:Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.Formula:C19H20N2O4Color and Shape:SolidMolecular weight:340.37THK-5117
CAS:THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.Formula:C19H19FN2O2Color and Shape:SolidMolecular weight:326.36OXi8007
CAS:OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.Formula:C26H24NNa2O10PColor and Shape:SolidMolecular weight:587.428Hydromethylthionine HBr
CAS:Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.Formula:C16H21Br2N3SColor and Shape:SolidMolecular weight:447.233(R)-TTBK1-IN-1
CAS:(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.Formula:C18H19N5O2Color and Shape:SolidMolecular weight:337.38Tubulin polymerization-IN-25
CAS:Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.Formula:C24H18N2O3SColor and Shape:SolidMolecular weight:414.48Tubulin polymerization-IN-15
CAS:Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].Formula:C18H17N3O4Color and Shape:SolidMolecular weight:339.35Tubulin polymerization-IN-20
CAS:Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.Formula:C25H24FNO5Color and Shape:SolidMolecular weight:437.46Tubulin inhibitor 18
CAS:"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."Formula:C22H26O5Color and Shape:SolidMolecular weight:370.44Tubulin/MMP-IN-1
Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.Formula:C38H44NO9PColor and Shape:SolidMolecular weight:689.73Tubulin inhibitor 12
CAS:New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.Formula:C24H20N2OColor and Shape:SolidMolecular weight:352.43Tau tracer 1
CAS:Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.Formula:C34H23N5O2Color and Shape:SolidMolecular weight:533.591Iso-Fludelone
CAS:Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.Formula:C27H36F3NO6Color and Shape:SolidMolecular weight:527.57Antitumor agent-68
CAS:Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.Formula:C17H11NO2Color and Shape:SolidMolecular weight:261.27Antitumor agent-71
CAS:Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.Formula:C26H31N5O4SColor and Shape:SolidMolecular weight:509.62IDT
CAS:IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Formula:C8H5NS2Purity:98%Color and Shape:SolidMolecular weight:179.26DHNQ
CAS:DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).Formula:C18H14N2OColor and Shape:SolidMolecular weight:274.32D011-2120
CAS:D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.Formula:C17H15NO3Purity:98%Color and Shape:SolidMolecular weight:281.31DAT1
CAS:DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.Formula:C17H15N3O2SPurity:98%Color and Shape:SolidMolecular weight:325.38Acodazole
CAS:Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.Formula:C20H19N5OPurity:98%Color and Shape:SolidMolecular weight:345.4Acodazole hydrochloride
CAS:Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.Formula:C20H20ClN5OPurity:98%Color and Shape:SolidMolecular weight:381.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Formula:C15H11FN4OSPurity:98%Color and Shape:SolidMolecular weight:314.34GF 15
CAS:GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.Formula:C23H21ClO6Purity:98%Color and Shape:SolidMolecular weight:428.86TOK-8801
CAS:TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.Formula:C17H21N3OSPurity:99.97%Color and Shape:SolidMolecular weight:315.43Alyssin, (R)-
CAS:Alyssin, (R)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Formula:C7H13NOS2Color and Shape:SolidMolecular weight:191.31Cemadotin hydrochloride
CAS:Cemadotin hydrochloride (LU103793) is a synthetic mitosis inhibitor derived from Dolastatin 15 for treating solid tumors.Formula:C35H57ClN6O5Color and Shape:SolidMolecular weight:677.33Alyssin, (S)-
CAS:Alyssin, (S)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Formula:C7H13NOS2Color and Shape:SolidMolecular weight:191.31OX01914
CAS:OX01914 is a soluble modulator to increase utrophin in DMD studies, EC50 20.5 μM.Formula:C17H14N4OColor and Shape:SolidMolecular weight:290.32
