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Microtubule Associated

Microtubule Associated

Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.

Found 261 products of "Microtubule Associated"

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  • O-GlcNAcase-IN-4
    Targetmol
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    O-GlcNAcase-IN-4

    CAS:
    <p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>
    Formula:C16H22FN5O3S
    Color and Shape:Solid
    Molecular weight:383.44

    Ref: TM-T61662

  • Tubulin polymerization-IN-18
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    Tubulin polymerization-IN-18

    CAS:
    <p>Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.</p>
    Formula:C25H25NO6
    Color and Shape:Solid
    Molecular weight:435.47

    Ref: TM-T62477

  • Synstab A
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    Synstab A

    CAS:
    <p>Synstab A is a microtubule stabilizer.</p>
    Formula:C15H13BrCl3N3O3S
    Color and Shape:Solid
    Molecular weight:501.61

    Ref: TM-T34759

  • Microtubule inhibitor 7
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    Microtubule inhibitor 7

    CAS:
    <p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>
    Formula:C25H19FN2O5
    Color and Shape:Solid
    Molecular weight:446.43

    Ref: TM-T62639

  • (S)-Dolaphenine hydrochloride
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    (S)-Dolaphenine hydrochloride

    CAS:
    <p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>
    Formula:C11H13ClN2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:240.75

    Ref: TM-T19620

  • Deox B 7,4
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    Deox B 7,4

    CAS:
    <p>Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.</p>
    Formula:C18H18O5
    Color and Shape:Solid
    Molecular weight:314.33

    Ref: TM-T23978

  • Tubulin polymerization-IN-30
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    Tubulin polymerization-IN-30

    CAS:
    <p>Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.</p>
    Formula:C22H25N5O3
    Color and Shape:Solid
    Molecular weight:407.47

    Ref: TM-T62040

  • Tubulin inhibitor 29
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    Tubulin inhibitor 29

    CAS:
    <p>Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.</p>
    Formula:C12H8F2O2S2
    Color and Shape:Solid
    Molecular weight:286.32

    Ref: TM-T60568

  • Microtubule inhibitor 6
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    Microtubule inhibitor 6

    CAS:
    <p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>
    Formula:C24H19FN2O5
    Color and Shape:Solid
    Molecular weight:434.42

    Ref: TM-T62448

  • Tubulin inhibitor 31
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    Tubulin inhibitor 31

    <p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>
    Formula:C22H19NO2
    Color and Shape:Solid
    Molecular weight:329.39

    Ref: TM-T72449

  • Tubulin polymerization-IN-7
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    Tubulin polymerization-IN-7

    CAS:
    <p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>
    Formula:C28H24N4O6S
    Color and Shape:Solid
    Molecular weight:544.58

    Ref: TM-T63836

  • Anticancer agent 60
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    Anticancer agent 60

    CAS:
    <p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>
    Formula:C27H33N5O4S
    Color and Shape:Solid
    Molecular weight:523.65

    Ref: TM-T63671

  • SB26019
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    SB26019

    CAS:
    <p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>
    Formula:C24H20O4
    Color and Shape:Solid
    Molecular weight:372.41

    Ref: TM-T75013

  • AMXI-5001
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    AMXI-5001

    CAS:
    <p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>
    Formula:C25H20FN5O3
    Color and Shape:Solid
    Molecular weight:457.46

    Ref: TM-T62847

  • Tubulin inhibitor 20
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    Tubulin inhibitor 20

    CAS:
    <p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>
    Formula:C19H18O4
    Color and Shape:Solid
    Molecular weight:310.34

    Ref: TM-T60755

  • Tubulin inhibitor 26
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    Tubulin inhibitor 26

    CAS:
    <p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>
    Formula:C17H19N3O3
    Color and Shape:Solid
    Molecular weight:313.35

    Ref: TM-T60793

  • Microtubule inhibitor 5
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    Microtubule inhibitor 5

    CAS:
    <p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>
    Formula:C22H15FN2O4
    Color and Shape:Solid
    Molecular weight:390.36

    Ref: TM-T61765

  • Tubulin polymerization-IN-37
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    Tubulin polymerization-IN-37

    CAS:
    <p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>
    Formula:C19H20N2O4
    Color and Shape:Solid
    Molecular weight:340.37

    Ref: TM-T61084

  • THK-5117
    Targetmol
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    THK-5117

    CAS:
    <p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>
    Formula:C19H19FN2O2
    Color and Shape:Solid
    Molecular weight:326.36

    Ref: TM-T60907

  • OXi8007
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    OXi8007

    CAS:
    <p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>
    Formula:C26H24NNa2O10P
    Color and Shape:Solid
    Molecular weight:587.428

    Ref: TM-T64157

  • Hydromethylthionine HBr
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    Hydromethylthionine HBr

    CAS:
    <p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>
    Formula:C16H21Br2N3S
    Color and Shape:Solid
    Molecular weight:447.233

    Ref: TM-T68257

  • (R)-TTBK1-IN-1
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    (R)-TTBK1-IN-1

    CAS:
    <p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s &amp; tauopathies.</p>
    Formula:C18H19N5O2
    Color and Shape:Solid
    Molecular weight:337.38

    Ref: TM-T72808

  • Tubulin polymerization-IN-25
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    Tubulin polymerization-IN-25

    CAS:
    <p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) &amp; FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>
    Formula:C24H18N2O3S
    Color and Shape:Solid
    Molecular weight:414.48

    Ref: TM-T62135

  • Tubulin polymerization-IN-15
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    Tubulin polymerization-IN-15

    CAS:
    <p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>
    Formula:C18H17N3O4
    Color and Shape:Solid
    Molecular weight:339.35

    Ref: TM-T61069

  • Tubulin polymerization-IN-20
    Targetmol
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    Tubulin polymerization-IN-20

    CAS:
    <p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>
    Formula:C25H24FNO5
    Color and Shape:Solid
    Molecular weight:437.46

    Ref: TM-T62498

  • Tubulin inhibitor 18
    Targetmol
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    Tubulin inhibitor 18

    CAS:
    <p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>
    Formula:C22H26O5
    Color and Shape:Solid
    Molecular weight:370.44

    Ref: TM-T61472

  • Tubulin/MMP-IN-1
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    Tubulin/MMP-IN-1

    <p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>
    Formula:C38H44NO9P
    Color and Shape:Solid
    Molecular weight:689.73

    Ref: TM-T72676

  • Tubulin inhibitor 12
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    Tubulin inhibitor 12

    CAS:
    <p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>
    Formula:C24H20N2O
    Color and Shape:Solid
    Molecular weight:352.43

    Ref: TM-T61242

  • Tau tracer 1
    Targetmol
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    Tau tracer 1

    CAS:
    <p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>
    Formula:C34H23N5O2
    Color and Shape:Solid
    Molecular weight:533.591

    Ref: TM-T39660

  • Iso-Fludelone
    Targetmol
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    Iso-Fludelone

    CAS:
    <p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>
    Formula:C27H36F3NO6
    Color and Shape:Solid
    Molecular weight:527.57

    Ref: TM-T68860

  • KIF18A-IN-4
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    KIF18A-IN-4

    CAS:
    <p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>
    Formula:C22H27N3O3S
    Color and Shape:Solid
    Molecular weight:413.53

    Ref: TM-T62118

  • Antitumor agent-68
    Targetmol
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    Antitumor agent-68

    CAS:
    <p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>
    Formula:C17H11NO2
    Color and Shape:Solid
    Molecular weight:261.27

    Ref: TM-T60421

  • Antitumor agent-71
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    Antitumor agent-71

    CAS:
    <p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>
    Formula:C26H31N5O4S
    Color and Shape:Solid
    Molecular weight:509.62

    Ref: TM-T63513

  • IDT
    Targetmol
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    IDT

    CAS:
    <p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>
    Formula:C8H5NS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:179.26

    Ref: TM-T25525

  • DHNQ
    Targetmol
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    DHNQ

    CAS:
    <p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>
    Formula:C18H14N2O
    Color and Shape:Solid
    Molecular weight:274.32

    Ref: TM-T27163

  • D011-2120
    Targetmol
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    D011-2120

    CAS:
    <p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>
    Formula:C17H15NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:281.31

    Ref: TM-T23933

  • DAT1
    Targetmol
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    DAT1

    CAS:
    <p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>
    Formula:C17H15N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:325.38

    Ref: TM-T25290

  • Acodazole
    Targetmol
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    Acodazole

    CAS:
    <p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>
    Formula:C20H19N5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:345.4

    Ref: TM-T23619

  • Acodazole hydrochloride
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    Acodazole hydrochloride

    CAS:
    <p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>
    Formula:C20H20ClN5O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:381.86

    Ref: TM-T23619L

  • LDN-193665
    Targetmol
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    LDN-193665

    CAS:
    <p>LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.</p>
    Formula:C15H11FN4OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:314.34

    Ref: TM-T25650

  • GF 15
    Targetmol
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    GF 15

    CAS:
    <p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>
    Formula:C23H21ClO6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:428.86

    Ref: TM-T11395

  • TOK-8801
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    TOK-8801

    CAS:
    <p>TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.</p>
    Formula:C17H21N3OS
    Purity:99.97%
    Color and Shape:Solid
    Molecular weight:315.43

    Ref: TM-T13180

  • Mivobulin
    Targetmol
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    Mivobulin

    CAS:
    <p>Mivobulin is an inhibitor of tubulin .</p>
    Formula:C17H19N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:325.37

    Ref: TM-T12052

  • S-methyl DM1
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    S-methyl DM1

    CAS:
    <p>S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.</p>
    Formula:C36H50ClN3O10S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:752.31

    Ref: TM-T12805

  • Cevipabulin
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    Cevipabulin

    CAS:
    <p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>
    Formula:C18H18ClF5N6O
    Purity:99.53%
    Color and Shape:Solid
    Molecular weight:464.82

    Ref: TM-T10772

  • Tau-aggregation and neuroinflammation-IN-1
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    Tau-aggregation and neuroinflammation-IN-1

    CAS:
    <p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>
    Formula:C25H20N2O7
    Purity:99.85%
    Color and Shape:Solid
    Molecular weight:460.44

    Ref: TM-T62899

  • CCB02
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    CCB02

    CAS:
    <p>CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.</p>
    Formula:C14H9N3O
    Purity:98.38%
    Color and Shape:Solid
    Molecular weight:235.24

    Ref: TM-T10704

  • S516
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    S516

    CAS:
    <p>S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.</p>
    Formula:C21H19N5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:437.47

    Ref: TM-T12823

  • Tubulin inhibitor 8
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    Tubulin inhibitor 8

    CAS:
    <p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>
    Formula:C21H14N2O3
    Purity:98.51% - 99.87%
    Color and Shape:Solid
    Molecular weight:342.35

    Ref: TM-T13226

  • TCS 2210
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    TCS 2210

    CAS:
    <p>TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.</p>
    Formula:C18H17N3O3
    Purity:98.62%
    Color and Shape:Solid
    Molecular weight:323.35

    Ref: TM-T23446