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Microtubule Associated

Microtubule Associated

Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.

Found 261 products of "Microtubule Associated"

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  • TTBK1/2-IN-3
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    TTBK1/2-IN-3

    CAS:
    <p>TTBK1/2-IN-3 (compound 10) is a potent inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 579 nM and 258 nM, respectively. TTBK1/2-IN-3 can reduce the expression of primary cilia on the surface of human induced pluripotent stem cells (iPSC).</p>
    Formula:C21H22N4O
    Color and Shape:Solid
    Molecular weight:346.426

    Ref: TM-T206217

  • PM-060184
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    PM-060184

    CAS:
    <p>PM-060184, a tubulin polymerisation inhibitor, is used potentially for the treatment of solid tumours and breast cancer.</p>
    Formula:C31H45N3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:571.7

    Ref: TM-T28428

  • Tubulin polymerization-IN-8
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    Tubulin polymerization-IN-8

    CAS:
    <p>Compound IIc inhibits tubulin polymerization, arrests cell cycle at G2/M in HCT116 cells, IC50 12.7 μM, potential for cancer research.</p>
    Formula:C21H24N4O4S
    Color and Shape:Solid
    Molecular weight:428.5

    Ref: TM-T62349

  • Epothilone E
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    Epothilone E

    CAS:
    <p>Epothilone E, a derivative of epothilone, functions by inhibiting microtubule protein activity, thereby halting cell division and exhibiting anti-tumor</p>
    Formula:C26H39NO7S
    Color and Shape:Solid
    Molecular weight:509.66

    Ref: TM-T72934

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    Fosbretabulin tromethamine

    CAS:
    Formula:C22H32NO11P
    Molecular weight:517.46

    Ref: TM-T210328

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    Tubulin inhibitor 15

    <p>Tubulin inhibitor 15 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 15 exhibits cytotoxicity in HepG2 cells [1].</p>
    Formula:C16H12FNO2
    Color and Shape:Solid
    Molecular weight:269.27

    Ref: TM-T60459

  • Tubulin polymerization-IN-75
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    Tubulin polymerization-IN-75

    CAS:
    <p>Tubulin polymerization-IN-75 (Compound 6) is an inhibitor of tubulin polymerization, with an IC50 value of 30 μM. It effectively suppresses the proliferation of cancer cells Huh7 and 293T, demonstrating IC50 values of 14.3 μM and 13.8 μM, respectively.</p>
    Formula:C14H11NO
    Color and Shape:Solid
    Molecular weight:209.243

    Ref: TM-T204231

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    PROTAC α-synuclein degrader 6

    CAS:
    <p>PROTACα-synuclein degrader 6 (compound T3) is a PROTAC degrader of α-synuclein and tau, with an EC50 of 1.57 μM and 4.09 μM, respectively. This compound plays a significant role in neurodegenerative disease (ND) research.</p>
    Formula:C37H39N5O9S
    Molecular weight:729.80

    Ref: TM-T209298

  • Ombrabulin
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    Ombrabulin

    CAS:
    <p>Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.</p>
    Formula:C21H26N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:402.44

    Ref: TM-T16387

    1mg
    Discontinued
    Discontinued product
  • Tau tracer 2
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    Tau tracer 2

    CAS:
    <p>Tau tracer 2 (Pl-2620) is a specific imaging agent designed to detect and visualize Tau protein aggregates, primarily used for diagnosing neurodegenerative diseases [1].</p>
    Formula:C15H9FN4
    Color and Shape:Solid
    Molecular weight:264.263

    Ref: TM-T37051

    ne
    Discontinued
    Discontinued product
  • Cevipabulin fumarate
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    Cevipabulin fumarate

    CAS:
    <p>Cevipabulin (TTI-237) fumarate is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).</p>
    Formula:C22H22ClF5N6O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:580.89

    Ref: TM-T10772L

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product