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Microtubule Associated

Microtubule Associated

Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.

Found 261 products of "Microtubule Associated"

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  • MAP4343
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    MAP4343

    CAS:
    <p>Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.</p>
    Formula:C22H34O2
    Purity:97.024%
    Color and Shape:Solid
    Molecular weight:330.5

    Ref: TM-T9504

  • Suprafenacine
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    Suprafenacine

    CAS:
    <p>Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that induces</p>
    Formula:C16H18N4O
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:282.34

    Ref: TM-T28886

  • MMAF
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    MMAF

    CAS:
    <p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>
    Formula:C39H65N5O8
    Purity:97.00% - 99.88%
    Color and Shape:Solid
    Molecular weight:731.96

    Ref: TM-T3256

  • LP-261
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    LP-261

    CAS:
    <p>LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.</p>
    Formula:C22H19N3O4S
    Purity:99.91%
    Color and Shape:Solid
    Molecular weight:421.47

    Ref: TM-T9595

  • Tirbanibulin
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    Tirbanibulin

    CAS:
    <p>Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.</p>
    Formula:C26H29N3O3
    Purity:99.43% - 99.67%
    Color and Shape:Solid
    Molecular weight:431.53

    Ref: TM-T6345

  • D-64131
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    D-64131

    CAS:
    <p>D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.</p>
    Formula:C16H13NO2
    Purity:99.48% - 99.67%
    Color and Shape:Solid
    Molecular weight:251.28

    Ref: TM-T1753

  • Clanfenur
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    Clanfenur

    CAS:
    <p>Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.</p>
    Formula:C16H15ClFN3O2
    Purity:99.93%
    Color and Shape:Solid
    Molecular weight:335.76

    Ref: TM-T5448

  • Valecobulin
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    Valecobulin

    CAS:
    <p>Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.</p>
    Formula:C26H28N6O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:536.6

    Ref: TM-T13278L

  • 4-Isopropoxybenzoic acid
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    4-Isopropoxybenzoic acid

    CAS:
    <p>4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.</p>
    Formula:C10H12O3
    Purity:99.88%
    Color and Shape:White To Off-White Powder
    Molecular weight:180.2

    Ref: TM-T24977

  • NQTrp
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    NQTrp

    CAS:
    <p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>
    Formula:C21H16N2O4
    Purity:98.35%
    Color and Shape:Solid
    Molecular weight:360.36

    Ref: TM-T22118

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    Semorinemab

    CAS:
    <p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>
    Purity:95% - 95%
    Color and Shape:Liquid

    Ref: TM-T76886

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    Gosuranemab

    CAS:
    <p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>
    Purity:95% - 95%
    Color and Shape:Liquid

    Ref: TM-T77028

  • 4-Desacetylvinblastine hydrazide
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    4-Desacetylvinblastine hydrazide

    CAS:
    <p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>
    Formula:C43H56N6O7
    Color and Shape:Solid
    Molecular weight:768.94

    Ref: TM-T29434

  • ST-401
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    ST-401

    CAS:
    <p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>
    Formula:C24H20N2O
    Color and Shape:Solid
    Molecular weight:352.43

    Ref: TM-T88447

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    Posdinemab

    CAS:
    <p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>
    Color and Shape:Liquid

    Ref: TM-T80616

  • Tubulin polymerization-IN-2
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    Tubulin polymerization-IN-2

    CAS:
    <p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>
    Formula:C17H12F2N2O2
    Color and Shape:Solid
    Molecular weight:314.29

    Ref: TM-T60802

  • Auristatin F
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    Auristatin F

    CAS:
    <p>Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.</p>
    Formula:C40H67N5O8
    Purity:98.41% - 99.25%
    Color and Shape:Solid
    Molecular weight:745.99

    Ref: TM-T14349

  • Tubulin polymerization-IN-15
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    Tubulin polymerization-IN-15

    CAS:
    <p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>
    Formula:C18H17N3O4
    Color and Shape:Solid
    Molecular weight:339.35

    Ref: TM-T61069

  • DJ101
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    DJ101

    CAS:
    <p>DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.</p>
    Formula:C23H20N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.43

    Ref: TM-T24005

  • SB26019
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    SB26019

    CAS:
    <p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>
    Formula:C24H20O4
    Color and Shape:Solid
    Molecular weight:372.41

    Ref: TM-T75013