Microtubule Associated
Microtubule-associated protein inhibitors target proteins that interact with microtubules, the structural components of the cell's cytoskeleton that are essential for cell division. These proteins regulate the stability and dynamics of microtubules during mitosis. Inhibiting microtubule-associated proteins can disrupt microtubule function, leading to cell cycle arrest and apoptosis, particularly in rapidly dividing cancer cells. These inhibitors are widely used in cancer research and drug development. At CymitQuimica, we offer a comprehensive range of high-quality microtubule-associated protein inhibitors to support your research in cell division, cytoskeletal dynamics, and cancer therapy.
Found 274 products of "Microtubule Associated"
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Deox B 7,4
CAS:Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.Formula:C18H18O5Color and Shape:SolidMolecular weight:314.33Tubulin polymerization-IN-30
CAS:Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.Formula:C22H25N5O3Color and Shape:SolidMolecular weight:407.47Tubulin inhibitor 29
CAS:Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.Formula:C12H8F2O2S2Color and Shape:SolidMolecular weight:286.32Microtubule inhibitor 6
CAS:Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.Formula:C24H19FN2O5Color and Shape:SolidMolecular weight:434.42Tubulin inhibitor 31
Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.Formula:C22H19NO2Color and Shape:SolidMolecular weight:329.39Tubulin polymerization-IN-7
CAS:Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.Formula:C28H24N4O6SColor and Shape:SolidMolecular weight:544.58Anticancer agent 60
CAS:Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.Formula:C27H33N5O4SColor and Shape:SolidMolecular weight:523.65SB26019
CAS:SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.Formula:C24H20O4Color and Shape:SolidMolecular weight:372.41AMXI-5001
CAS:AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.Formula:C25H20FN5O3Color and Shape:SolidMolecular weight:457.46Tubulin inhibitor 20
CAS:Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].Formula:C19H18O4Color and Shape:SolidMolecular weight:310.34Tubulin inhibitor 26
CAS:Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.Formula:C17H19N3O3Color and Shape:SolidMolecular weight:313.35Microtubule inhibitor 5
CAS:Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.Formula:C22H15FN2O4Color and Shape:SolidMolecular weight:390.36Tubulin polymerization-IN-37
CAS:Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.Formula:C19H20N2O4Color and Shape:SolidMolecular weight:340.37THK-5117
CAS:THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.Formula:C19H19FN2O2Color and Shape:SolidMolecular weight:326.36OXi8007
CAS:OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.Formula:C26H24NNa2O10PColor and Shape:SolidMolecular weight:587.428Hydromethylthionine HBr
CAS:Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.Formula:C16H21Br2N3SColor and Shape:SolidMolecular weight:447.233(R)-TTBK1-IN-1
CAS:(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.Formula:C18H19N5O2Color and Shape:SolidMolecular weight:337.38Tubulin polymerization-IN-25
CAS:Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.Formula:C24H18N2O3SColor and Shape:SolidMolecular weight:414.48Tubulin polymerization-IN-15
CAS:Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].Formula:C18H17N3O4Color and Shape:SolidMolecular weight:339.35Tubulin polymerization-IN-20
CAS:Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.Formula:C25H24FNO5Color and Shape:SolidMolecular weight:437.46
