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DYRK

DYRK

DYRK (Dual-specificity Tyrosine Phosphorylation-regulated Kinase) inhibitors are compounds that target the DYRK family of kinases, which are involved in cell cycle regulation, neuronal development, and apoptosis. DYRK kinases have dual specificity, meaning they can phosphorylate both tyrosine and serine/threonine residues. Inhibiting DYRK kinases can affect various cellular processes, including cell cycle progression and differentiation. DYRK inhibitors are important tools in research on cancer, neurodegenerative diseases, and cell signaling. At CymitQuimica, we offer a selection of high-quality DYRK inhibitors to support your research in cell cycle control, neurobiology, and therapeutic development.

Found 48 products of "DYRK"

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  • FINDY
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    FINDY

    CAS:
    <p>FINDY selectively inhibits DYRK1A at 35 μM IC50, blocking Ser97 autophosphorylation, useful for neurological disorder research.</p>
    Formula:C16H17NO2S2Si
    Color and Shape:Solid
    Molecular weight:347.53

    Ref: TM-T73551

  • Dyrk1A-IN-5
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    Dyrk1A-IN-5

    CAS:
    <p>Potent DYRK1A inhibitor with IC50s: 6 nM overall, 0.5 μM SF3B1, 2.1 μM tau phosphorylation. Useful for Down syndrome studies.</p>
    Formula:C16H9IN2O2
    Color and Shape:Solid
    Molecular weight:388.16

    Ref: TM-T61739

  • JH-XIV-68-3
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    JH-XIV-68-3

    CAS:
    <p>JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.</p>
    Formula:C21H17F3N8O
    Color and Shape:Solid
    Molecular weight:454.41

    Ref: TM-T62790

  • LDN-209929 dihydrochloride
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    LDN-209929 dihydrochloride

    CAS:
    <p>LDN-209929 dihydrochloride: potent haspin kinase inhibitor, 55 nM IC50, 180x more selective than DYRK2.</p>
    Formula:C17H19Cl3N2OS
    Color and Shape:Solid
    Molecular weight:405.77

    Ref: TM-T62011

  • Dyrk1A-IN-3
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    Dyrk1A-IN-3

    CAS:
    <p>Dyrk1A-IN-3 is a selective DYRK1A inhibitor with an IC50 of 76 nM, useful for neurodegenerative disease research.</p>
    Formula:C18H16N6
    Color and Shape:Solid
    Molecular weight:316.36

    Ref: TM-T60824

  • tBID
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    tBID

    CAS:
    <p>tBID is a selective homeodomain-interacting protein kinase 2 (HIPK2) inhibitor (IC50 of 0.33 μM)</p>
    Formula:C11H3Br4N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:528.78

    Ref: TM-T13096

  • AnnH31
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    AnnH31

    CAS:
    <p>AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the</p>
    Formula:C15H13N3O
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:251.28

    Ref: TM-T26632

  • DYRKi
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    DYRKi

    CAS:
    <p>DYRKi is a nontoxic, DYRK1-selective inhibitor.</p>
    Formula:C20H13F3N4O2S
    Color and Shape:Solid
    Molecular weight:430.4

    Ref: TM-T27226

  • INDY
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    INDY

    CAS:
    <p>INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.</p>
    Formula:C12H13NO2S
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:235.3

    Ref: TM-T15579

  • ProINDY
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    ProINDY

    CAS:
    <p>ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome.</p>
    Formula:C14H15NO3S
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:277.34

    Ref: TM-T23186

  • CLK-IN-T3
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    CLK-IN-T3

    CAS:
    <p>CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.</p>
    Formula:C28H30N6O2
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:482.58

    Ref: TM-T14980

  • YK-2-69
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    YK-2-69

    CAS:
    <p>YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.</p>
    Formula:C25H27FN8OS
    Purity:98.61% - 99.64%
    Color and Shape:Solid
    Molecular weight:506.6

    Ref: TM-T69564

  • ML 315
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    ML 315

    CAS:
    <p>ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.</p>
    Formula:C18H13Cl2N3O2
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:374.22

    Ref: TM-T36707

  • DYRKs-IN-2
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    DYRKs-IN-2

    CAS:
    <p>DYRKs-IN-2 has antitumor activity. DYRKs-IN-2 is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively.</p>
    Formula:C32H38ClN9O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:632.16

    Ref: TM-T11133

  • Dyrk1A-IN-8
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    Dyrk1A-IN-8

    CAS:
    <p>Dyrk1A-IN-8 is an active molecule that can be used in life science related research. The CAS number of Dyrk1A-IN-8 is 101578-13-6.</p>
    Formula:C17H21N3O
    Color and Shape:Solid
    Molecular weight:283.37

    Ref: TM-T87614

  • DYRKs-IN-1
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    DYRKs-IN-1

    CAS:
    <p>DYRKs-IN-1 has antitumor activity.</p>
    Formula:C30H30ClN7O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:588.06

    Ref: TM-T11132

  • DYRKs-IN-1 hydrochloride
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    DYRKs-IN-1 hydrochloride

    CAS:
    <p>DYRKs-IN-1 HCl inhibits DYRK1A (5 nM IC50) &amp; DYRK1B (8 nM IC50) with antitumor properties.</p>
    Formula:C30H31Cl2N7O4
    Color and Shape:Solid
    Molecular weight:624.52

    Ref: TM-T72242

  • CymitQuimica logo
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    Dyrk1A-IN-2

    <p>Dyrk1A-IN-2 is a DYRK1A inhibitor (EC50: 37 nM). dyrk1A-IN-2 exhibits efficient promotion of human β-cell replication, as well as low cytotoxicity.</p>
    Formula:C27H32N6O4
    Color and Shape:Solid
    Molecular weight:504.58

    Ref: TM-T63440

  • Norharmine
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    Norharmine

    CAS:
    <p>Norharmine is an analogue of harman and functions as an alkaloid. It serves as an inhibitor of both monoamine oxidase A (MAO-A) and DYRK1A. While it exhibits weak inhibitory activity against MAO-A, it has certain inhibitory effects on DYRK1A.</p>
    Formula:C12H10N2O
    Color and Shape:Solid
    Molecular weight:198.221

    Ref: TM-T204194

  • CymitQuimica logo
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    Dyrk1A/α-synuclein-IN-1

    <p>Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual inhibitor of Dyrk1A (IC50: 177 nM) and α-synuclein aggregation (IC50: 10.5 μM).</p>
    Formula:C20H21N5O3S
    Color and Shape:Solid
    Molecular weight:411.48

    Ref: TM-T62096