HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Found 180 products of "HSP"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
BIIB021
CAS:BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).Formula:C14H15ClN6OPurity:98% - 99.82%Color and Shape:SolidMolecular weight:318.76Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Formula:C29H31NO7Purity:95.32% - 99.67%Color and Shape:SolidMolecular weight:505.56Ref: TM-TQ0131
1mg187.00€5mg410.00€10mg710.00€25mg1,381.00€50mg2,352.00€500µg155.00€1mL*10mM (DMSO)449.00€Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Formula:C32H48N4O8·HClPurity:99.94%Color and Shape:SolidMolecular weight:653.21Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37Alvespimycin
CAS:Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.Formula:C32H48N4O8Purity:99.88%Color and Shape:SolidMolecular weight:616.75Calenduloside E
CAS:Calenduloside E (Silphioside F) exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and byFormula:C36H56O9Purity:96.16% - 98.99%Color and Shape:SolidMolecular weight:632.8217-AEP-GA
CAS:17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.Formula:C34H50N4O8Purity:97.77% - 99.56%Color and Shape:SolidMolecular weight:642.78BF844
CAS:BF844 chemical counters USH3-induced hearing loss by transporting mutated CLRN1 to cell membranes, effectively preserving hearing in vivo.Formula:C21H19ClN4OColor and Shape:SolidMolecular weight:378.85HSP90-IN-12
CAS:VAC, a potent anti-cancer vibsanin A analog, inhibits cell proliferation and affects HSP90 protein levels.Formula:C25H36O4Color and Shape:SolidMolecular weight:400.55YM-01 Tosylate
CAS:YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.Formula:C27H27N3O4S3Color and Shape:SolidMolecular weight:553.72Displurigen
CAS:Displurigen is an inhibitor of ATPase activity of HSP70.Formula:C15H10O4SPurity:98%Color and Shape:SolidMolecular weight:286.3Malonganenone A
CAS:Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.Formula:C26H38N4O2Color and Shape:SolidMolecular weight:438.616BrCaQ
CAS:6BrCaQ inhibits TRAP1, has antiproliferative effects, and is used in 6BrCaQ-TPP synthesis.Formula:C18H15BrN2O3Color and Shape:SolidMolecular weight:387.23PU3
CAS:PU3 is an inhibitor of Hsp90.Formula:C19H25N5O3Purity:98%Color and Shape:SolidMolecular weight:371.43SEW84
CAS:SEW84, an Aha1-stimulated Hsp90 inhibitor, has an IC50 of 0.3 μM, aiding protein deposition disease research.Formula:C19H14F4N4OSColor and Shape:SolidMolecular weight:422.4HSP90-IN-14
CAS:HSP90-IN-14 inhibits Hsp90 (Kd=0.26 μM) and fights influenza A/H3N2, A/H1N1, B with EC50 of 2.6, 3.9, 17 μM in MDCK cells.Formula:C14H8Cl2N4O4SColor and Shape:SolidMolecular weight:399.21CH5164840
CAS:CH5164840: strong HSP90 blocker; excels in NSCLC treatment; boosts erlotinib efficacy on EGFR-mutant tumors.Formula:C19H23N5O2SColor and Shape:SolidMolecular weight:385.48Hsp90-Cdc37-IN-1
CAS:Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.Formula:C43H57FN2O6SPurity:98%Color and Shape:SolidMolecular weight:748.99Vibsanin A
CAS:Vibsanin A, an activator of protein kinase C (PKC) and an inhibitor of HSP90, demonstrates anti-proliferative effects on human cancer cell lines.Formula:C25H38O4Color and Shape:SolidMolecular weight:402.57YM-1
CAS:YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.Formula:C20H20ClN3OS2Color and Shape:SolidMolecular weight:417.98
